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Targeting vector-phospholipid conjugates 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-038/00
  • C07K-014/00
  • A61K-049/22
  • A61K-047/48
  • C07K-007/08
  • C07K-014/52
  • C07K-014/71
출원번호 US-0190860 (2014-02-26)
등록번호 US-9295737 (2016-03-29)
발명자 / 주소
  • Bussat, Philippe
  • Cherkaoui, Samir
  • Fan, Hong (Helen)
  • Lamy, Bernard
  • Nanjappan, Palaniappa
  • Pillai, Radhakrishna K.
  • Pochon, Sibylle
  • Song, Bo
  • Swenson, Rolf E.
출원인 / 주소
  • BRACCO SUISSE SA
대리인 / 주소
    Pearl Cohen Zedek Latzer Baratz LLP
인용정보 피인용 횟수 : 0  인용 특허 : 166

초록

Peptide vectors having high KDR binding affinity and processes for making such vectors are provided. The peptide vectors may be conjugated to phospholipids and included in ultrasound contrast agent compositions. Such ultrasound contrast agents are particularly useful in therapeutic and diagnostic me

대표청구항

1. A method of making a peptide phospholipid conjugate having less than or equal to 0.3% trifluoroacetic acid (TFA) comprising the steps of: converting a peptide TFA salt to an acetate salt via anion exchange; andconjugating the peptide to a phospholipid, wherein said phospholipid at the time of con

이 특허에 인용된 특허 (166)

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