최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
DataON 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Edison 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0519213 (2007-12-21) |
등록번호 | US-9302044 (2016-04-05) |
국제출원번호 | PCT/US2007/026194 (2007-12-21) |
§371/§102 date | 20090615 (20090615) |
국제공개번호 | WO2008/085421 (2008-07-17) |
발명자 / 주소 |
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출원인 / 주소 |
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대리인 / 주소 |
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인용정보 | 피인용 횟수 : 0 인용 특허 : 337 |
A system includes a parameter generation system to determine parameters of at least one phase of an injection procedure based at least in part upon a type of the injection procedure. The parameter generator system determines the amount of a pharmaceutical that is to be delivered to a patient at leas
A system includes a parameter generation system to determine parameters of at least one phase of an injection procedure based at least in part upon a type of the injection procedure. The parameter generator system determines the amount of a pharmaceutical that is to be delivered to a patient at least in part on the basis of the concentration of an agent in the pharmaceutical and at least on part on the basis of a function that depends upon and varies with a patient parameter. The patient parameter can, for example, be weight, body mass index, body surface area or cardiac output. The pharmaceutical can, for example, include a contrast enhancing agent for use in an imaging procedure.
1. A system, comprising: a first pressurizing drive member adapted to be operably associated with at least a first fluid container, the first fluid container being adapted to contain a pharmaceutical comprising a contrast enhancing agent to be injected in an imaging procedure; anda controller operab
1. A system, comprising: a first pressurizing drive member adapted to be operably associated with at least a first fluid container, the first fluid container being adapted to contain a pharmaceutical comprising a contrast enhancing agent to be injected in an imaging procedure; anda controller operably associated with the first pressurizing drive member, the controller comprising a programming system to allow programming of an injection protocol via which injection of the pharmaceutical from the at least a first fluid container is controlled, the injection protocol comprising at least a first phase;a parameter generation system in communication with the controller and comprising a processor, a memory system and an input system, the processor executing an algorithm stored in the memory system, the algorithm determining parameters of the at least a first phase of the injection protocol based at least in part upon a type of the injection protocol identified via the input system, wherein the parameter generation system determines a volume of the pharmaceutical that is to be delivered to a patient at least partly on the basis of a concentration of the contrast enhancing agent in the pharmaceutical identified via the input system and at least partly on the basis of a function X having a value that differs depending upon a weight of the patient input via the input system. 2. The system of claim 1 wherein at least a first portion V1 of the volume of the pharmaceutical to be delivered to the patient is calculated using the formula: V1=weight*X*Y, wherein Y is a function of the concentration of the contrast enhancing agent in the pharmaceutical. 3. The system of claim 2 wherein X is determined for the weight of a particular patient from an algorithm in which X is calculated as a function of weight. 4. The system of claim 2 wherein X is determined for the weight of a particular patient from a table wherein X is set forth as a function of weight. 5. The system of claim 2 further comprising: a second pressurizing drive member adapted to be operably associated with at least a second fluid container, the second fluid container adapted to contain a diluent fluid;wherein the controller is operably associated with the second pressurizing drive member, and wherein V1 is the volume of the pharmaceutical to be delivered in a phase in which only the pharmaceutical is to be delivered to the patient, the parameter generation system also determining a volume V2 of the pharmaceutical to be delivered in at least a second phase in which both the pharmaceutical and the diluent fluid are to be delivered to the patient. 6. The system of claim 5 wherein a flow rate of the pharmaceutical delivered in the first phase is approximately equal to a flow rate of an admixture of the pharmaceutical and the diluent fluid delivered in the second phase. 7. The system of claim 6 wherein the flow rate of the pharmaceutical is calculated by dividing V1 by an injection duration of the first phase. 8. The system of claim 7 wherein the injection duration of the first phase is determined by adding a factor K to a scan duration of an imaging system. 9. The system of claim 8 wherein K ranges from 0 to 10 seconds. 10. The system of claim 9 wherein a minimum for the injection duration of the first phase can be input into the parameter generation system. 11. The system of claim 10 wherein the flow rate of the pharmaceutical delivered in the first phase is calculated by dividing V1 by the injection duration of the first phase. 12. The system of claim 6 wherein the volume V2 of the pharmaceutical to be delivered to the patient in the second phase is calculated based at least in part on a parameter of the patient selected from the group consisting of weight, body mass index, body surface area, and cardiac output. 13. The system of claim 12 wherein the parameter generation system determines whether a total volume of the pharmaceutical to be delivered to the patient in all phases exceeds an available volume of the pharmaceutical available for delivery to the patient, the parameter generation system further comprising rules to reduce the total volume of the pharmaceutical if the total volume exceeds the available volume. 14. The system of claim 5 wherein a total volume of the pharmaceutical to be delivered to the patient in all phases is determined. 15. The system of claim 14 wherein an initial protocol determined by the parameter generation system to determine the total volume of the pharmaceutical to be delivered to the patient is adjusted based upon a characterization of a cardiovascular system of the patient. 16. The system of claim 15 wherein a test bolus of the pharmaceutical is performed to characterize the cardiovascular system of the patient. 17. The system of claim 16 wherein the initial protocol is adjusted at least in part on the basis of a time to peak enhancement of the test bolus. 18. The system of claim 16 wherein the initial protocol is adjusted at least in part on the basis of a time to peak enhancement of the test bolus and a level of enhancement of the peak enhancement. 19. The system of claim 2 wherein X decreases nonlinearly with increasing weight of the patient.
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