최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
DataON 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Edison 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0907507 (2013-05-31) |
등록번호 | US-9339222 (2016-05-17) |
발명자 / 주소 |
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출원인 / 주소 |
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대리인 / 주소 |
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인용정보 | 피인용 횟수 : 0 인용 특허 : 399 |
Systems and methods of use involving sensors having a particle-containing domain are provided for continuous analyte measurement in a host. In some embodiments, a continuous analyte measurement system is configured to be wholly, transcutaneously, intravascularly or extracorporeally implanted.
1. A system for continuous in vivo measurement of an analyte in a host, the system comprising: a continuous analyte sensor configured for implantation in a host and configured to generate a signal indicative of an analyte concentration; anda layer disposed over at least a portion of the sensor, wher
1. A system for continuous in vivo measurement of an analyte in a host, the system comprising: a continuous analyte sensor configured for implantation in a host and configured to generate a signal indicative of an analyte concentration; anda layer disposed over at least a portion of the sensor, wherein the layer comprises a particle-containing domain comprising a metal, wherein the particle-containing domain is configured to react with at least one interfering species. 2. The system of claim 1, wherein the particle-containing domain is more distal to the sensor than other domains of the layer. 3. The system of claim 1, wherein the particle-containing domain comprises at least one material selected from the group consisting of platinum, platinum-iridium, iridium, palladium, graphite, gold, silver, silver chloride, carbon, and conductive polymers. 4. The system of claim 1, wherein the metal comprises sputtered metal. 5. The system of claim 4, wherein the sputtered metal is platinum. 6. The system of claim 1, wherein the particle-containing domain comprises a conductive particles concentration that is sufficient for the particle-containing domain to function as a conductive film. 7. The system of claim 1, wherein the particle-containing domain is configured to reduce flux therethrough of hydrogen peroxide. 8. The system of claim 1, wherein the particle-containing domain is non-powered. 9. The system of claim 1, wherein the particle-containing domain is powered. 10. The system of claim 9, wherein the sensor electronics are configured to apply a potential to the particle-containing domain. 11. The system of claim 1, wherein the layer comprises an analyte-permeable polymer. 12. The system of claim 11, wherein the analyte-permeable polymer comprises a hydrophilic polymer. 13. The system of claim 11, wherein the analyte-permeable polymer comprises at least one of polyurethane or silicone. 14. The system of claim 1, wherein the interfering species interferes with measurement of the analyte concentration to produce a signal that does not accurately represent the analyte concentration. 15. The system of claim 1, wherein the interfering species is a reactive metabolic species. 16. The system of claim 1, wherein the interfering species is a reactive oxygen species. 17. The system of claim 1, wherein the interfering species is a reactive nitrogen species. 18. The system of claim 1, wherein the interfering species is H2O2.
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