Methods and systems for ultra-trace analysis of liquids
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
G01N-001/10
C12M-001/34
C12Q-001/14
C12Q-001/70
C12Q-001/04
G01N-033/18
E21B-049/08
G01N-001/40
G01N-033/24
출원번호
US-0695395
(2011-05-04)
등록번호
US-9341609
(2016-05-17)
국제출원번호
PCT/US2011/035255
(2011-05-04)
§371/§102 date
20121030
(20121030)
국제공개번호
WO2011/140270
(2011-11-10)
발명자
/ 주소
Halden, Rolf U.
출원인 / 주소
ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY
대리인 / 주소
Leone, George A.
인용정보
피인용 횟수 :
0인용 특허 :
17
초록▼
A monitoring assembly (201) with an intake (213) has at least one pump (210) featuring at least one pump channel mounted in the monitoring assembly (201). A plurality of fluid lines are coupled to the at least one pump (210). At least one filter cartridge (315) is also mounted in the assembly. Each
A monitoring assembly (201) with an intake (213) has at least one pump (210) featuring at least one pump channel mounted in the monitoring assembly (201). A plurality of fluid lines are coupled to the at least one pump (210). At least one filter cartridge (315) is also mounted in the assembly. Each filter cartridge (315) is separately coupled by one of the plurality of fluid lines to one of the pump channels, where each filter cartridge (315) contains material for extracting an analyte, and where the at least one pump operates to separately push fluid through the at least one filter cartridge (315). The filter cartridge (315) operates to separate fluid into constituent parts.
대표청구항▼
1. A method for monitoring comprising: locating an assembly in a well including at least one pump and at least one filter cartridge module wherein each filter cartridge module includes a plurality of filter cartridges;connecting the at least one filter cartridge module through a plurality of pump ch
1. A method for monitoring comprising: locating an assembly in a well including at least one pump and at least one filter cartridge module wherein each filter cartridge module includes a plurality of filter cartridges;connecting the at least one filter cartridge module through a plurality of pump channels to the at least one pump;operating the at least one pump to push water through each of the plurality of filter cartridges at a predetermined flow rate, where each of the plurality of filter cartridges holds material for extracting an analyte; andwherein the plurality of filter cartridges operates to separate fluid into constituent parts;pumping water at a predetermined flow rate through the at least one filter cartridge module to produce pre-conditioned water;passing the preconditioned water through at least one microcosm, then passing water flowing through the at least one microcosm through at least one additional in-line filter cartridge to collect select microorganisms, select chemicals, or both. 2. The method of claim 1 further comprising incorporating at least one environmental/extraction module to receive fluid flowing through the at least one filter cartridge module. 3. The method of claim 1 where the extraction material is selected for extracting chemicals from the group consisting of ion-exchange resins, hydrophilic-hydrophobic interaction polymers, activated carbon, molecular imprinted polymers, polymers featuring analyte-specific docking sites, and combinations thereof. 4. The method of claim 1 where the extraction material is selected from the group consisting of cellulose inorganic polymers, organic polymers, acetate, nylon, polytetrafluoroethene (PTFE), metal screens, polyamide membranes, and molecular weight cutoff filters, and combinations thereof. 5. The method of claim 1 wherein the extraction material is selected for extracting chemical analytes selected from the group consisting of metals, alkali metals, alkaline earth metals, lanthanides, actinides, transition metals, metals and metalloids in the dissolved and particulate state and in various oxidation states, cesium, magnesium, silver, arsenic, copper, iron, and alloys thereof, radionuclides in the dissolved and particulate state and in various oxidation states, uranium, plutonium, halogens, noble gases, in the dissolved and particulate state and in various oxidation states including Cl—, P, I, argon, inorganic compounds, nitrate, perchlorate, and combinations thereof and organic compounds, chloroethenes, PCBs, dioxins, phthalates, pesticides, nitrosodimethyl amine, NDMA, and combinations thereof. 6. The method of claim 1 wherein the extraction material is selected for extracting biological analytes of natural and artificial origin selected from the group consisting of proteins, lipids, DNA, RNA, viruses, norovirus, HIV, hepatitis viruses, MS2 bacteriophage, enteric viruses, non-naturally occurring engineered infectious particles, bacteria, E. coli, Salmonella, Streptococci, Legionella, spore-forming organisms, Bacilli, Clostridia and their respective spores, Fungi and molds, Aspergillus niger, fungal spores, parasites, Cryptosporidium spp., Microsporidium spp., oocysts of parasites, Giardia lamblia, prions including PrPSc. 7. The method of claim 1 further comprising connecting at least one sensing unit to receive fluid from the plurality of filter cartridges. 8. The method of claim 1 further comprising connecting at least one sensing unit to receive fluid from at least one of the plurality of filter cartridge modules, where the at least one sensing unit includes sensors selected from the group consisting of real-time sensors, monitoring equipment, acidity (pH), oxidation/reduction potential (Eh), dissolved oxygen (DO), ion-specific electrodes and chemical sensors, a temperature sensor, an ion-specific electrode, a biochemical sensor, an electrochemical sensor, a tuning fork sensor, and combinations thereof. 9. The method of claim 7 wherein the at least one sensing unit transmits data to a monitoring system. 10. The method of claim 1 wherein the at least one pump comprises at least one peristaltic pump. 11. The method of claim 2 wherein the at least one environmental/extraction module comprises a test bed module including at least one test bed. 12. The method of claim 1 further comprising: capturing suspended microbes on a solid medium or on a filtration disk; andreversing the flow direction of the water to flush the concentrated microbes into a microcosm. 13. The method of claim 1 further comprising operating a first valve for backwashing of the filter cartridge; and operating a second valve to bypass the filter cartridge.
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