System and method for quality assurance in pathology
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
G06T-007/00
G06K-009/00
G06K-009/03
G06T-005/00
G02B-021/36
출원번호
US-0841548
(2015-08-31)
등록번호
US-9349036
(2016-05-24)
발명자
/ 주소
Soenksen, Dirk G.
Zirker-Smith, Kathy
출원인 / 주소
LEICA BIOSYSTEMS IMAGING, INC.
대리인 / 주소
Procopio, Cory, Hargreaves & Savitch LLP
인용정보
피인용 횟수 :
0인용 특허 :
63
초록▼
Enhancing color(s) in a digital slide image to increase contrast. In an embodiment, a digital slide image of a tissue sample is acquired. The tissue sample is counterstained, such that the digital slide image comprises an image of a first stain and a second stain. The contrast between the first stai
Enhancing color(s) in a digital slide image to increase contrast. In an embodiment, a digital slide image of a tissue sample is acquired. The tissue sample is counterstained, such that the digital slide image comprises an image of a first stain and a second stain. The contrast between the first stain and the second stain is increased to enhance the digital slide image.
대표청구항▼
1. A method comprising using at least one hardware processor to: acquire a digital slide image of a tissue sample that is counterstained with at least a first stain and a second stain, such that the digital slide image comprises an image of the first stain and the second stain; andincrease a contras
1. A method comprising using at least one hardware processor to: acquire a digital slide image of a tissue sample that is counterstained with at least a first stain and a second stain, such that the digital slide image comprises an image of the first stain and the second stain; andincrease a contrast between the first stain and the second stain within the digital slide image to enhance the digital slide image. 2. The method of claim 1, wherein increasing the contrast between the first stain and the second stain comprises changing a color of at least one of the first stain and the second stain. 3. The method of claim 1, further comprising using the at least one hardware processor to, prior to increasing the contrast, automatically determine whether or not a quality of the digital slide image is sufficient for diagnosis. 4. The method of claim 3, wherein determining whether or not a quality of the digital slide image is sufficient for diagnosis comprises comparing one or more characteristics of the digital slide image to a predetermined set of one or more criteria. 5. The method of claim 3, wherein increasing the contrast is performed automatically when the determination is that the quality of the digital slide image is sufficient. 6. The method of claim 1, further comprising using the at least one hardware processor to input the enhanced digital slide image into a clinical decision support system that guides a user through an interpretation of the tissue sample to arrive at a diagnosis. 7. A system comprising: at least one hardware processor; andone or more software modules that, when executed by the at least one hardware processor, acquire a digital slide image of a tissue sample that is counterstained with at least a first stain and a second stain, such that the digital slide image comprises an image of the first stain and the second stain, andincrease a contrast between the first stain and the second stain within the digital slide image to enhance the digital slide image. 8. The system of claim 7, wherein increasing the contrast between the first stain and the second stain comprises changing a color of at least one of the first stain and the second stain. 9. The system of claim 7, wherein the one or more software modules, prior to increasing the contrast, automatically determine whether or not a quality of the digital slide image is sufficient for diagnosis. 10. The system of claim 9, wherein determining whether or not a quality of the digital slide image is sufficient for diagnosis comprises comparing one or more characteristics of the digital slide image to a predetermined set of one or more criteria. 11. The system of claim 9, wherein the one or more software modules increase the contrast automatically when the determination is that the quality of the digital slide image is sufficient. 12. The system of claim 7, wherein the one or more software modules input the enhanced digital slide image into a clinical decision support system that guides a user through an interpretation of the tissue sample to arrive at a diagnosis. 13. The system of claim 7, wherein the at least one hardware processor is comprised in a slide scanner. 14. The system of claim 13, wherein the one or more software modules are stored in a memory of the slide scanner. 15. A non-transitory computer-readable medium having instructions stored thereon, wherein the instructions, when executed by a processor, cause the processor to: acquire a digital slide image of a tissue sample that is counterstained with at least a first stain and a second stain, such that the digital slide image comprises an image of the first stain and the second stain; andincrease a contrast between the first stain and the second stain within the digital slide image to enhance the digital slide image. 16. The non-transitory computer-readable medium of claim 15, wherein increasing the contrast between the first stain and the second stain comprises changing a color of at least one of the first stain and the second stain. 17. The non-transitory computer-readable medium of claim 15, wherein the instructions further cause the processor to, prior to increasing the contrast, automatically determine whether or not a quality of the digital slide image is sufficient for diagnosis. 18. The non-transitory computer-readable medium of claim 17, wherein determining whether or not a quality of the digital slide image is sufficient for diagnosis comprises comparing one or more characteristics of the digital slide image to a predetermined set of one or more criteria. 19. The non-transitory computer-readable medium of claim 17, wherein the instructions cause the processor to increase the contrast automatically when the determination is that the quality of the digital slide image is sufficient. 20. The non-transitory computer-readable medium of claim 15, wherein the instructions further cause the processor to input the enhanced digital slide image into a clinical decision support system that guides a user through an interpretation of the tissue sample to arrive at a diagnosis.
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