Described herein are vascular remodeling devices that include a proximal section, an intermediate section, and a distal section. During deployment, the proximal section can expand from a compressed delivery state to an expanded state and anchors the device in an afferent vessel of a bifurcation. The
Described herein are vascular remodeling devices that include a proximal section, an intermediate section, and a distal section. During deployment, the proximal section can expand from a compressed delivery state to an expanded state and anchors the device in an afferent vessel of a bifurcation. The distal section expands from the compressed delivery state to an expanded state that may be substantially planar, approximately semi-spherical, umbrella shaped, or reverse umbrella shaped. The distal section is positioned in a bifurcation junction across the neck of an aneurysm or within an aneurysm. The intermediate section allows perfusion to efferent vessels. Before or after the device is in position, embolic material may be used to treat the aneurysm. The distal section can act as a scaffolding to prevent herniation of the embolic material. The device can be used for clot retrieval with integral distal embolic protection.
대표청구항▼
1. An intraluminal device comprising: a proximal section configured to anchor in an afferent vessel;an intermediate section comprising a plurality of struts configured to allow perfusion to efferent vessels; anda distal section configured to act as a scaffolding to inhibit herniation of objects out
1. An intraluminal device comprising: a proximal section configured to anchor in an afferent vessel;an intermediate section comprising a plurality of struts configured to allow perfusion to efferent vessels; anda distal section configured to act as a scaffolding to inhibit herniation of objects out of a neck of a bifurcation aneurysm, the distal section forming a circumferentially continuous structure with a plurality of undulating filaments;wherein each of the plurality of struts is coupled at a coupling to the distal section at a region between a proximal end of the distal section and a distal end of the distal section;wherein the distal section is biased to transition from a first configuration to a second configuration such that the distal end of the distal section moves radially inwardly and retracts proximally relative to the proximal end of the distal section when released from a catheter. 2. The device of claim 1, wherein the proximal section comprises a hybrid cell design comprising open cells and closed cells. 3. The device of claim 1, wherein the proximal section comprises a plurality of repeating unit cells. 4. The device of claim 3, wherein the distal section comprises at least one said unit cell and at least partially forms a semi-sphere, umbrella, or reverse umbrella in an expanded state. 5. The device of claim 1, wherein the proximal section comprises a plurality of woven filaments. 6. The device of claim 1, wherein the proximal section comprises at least one tapered portion. 7. The device of claim 1, wherein the proximal section has a length between about 5 mm and about 30 mm. 8. The device of claim 1, wherein the proximal section has a length between about 10 mm and about 20 mm. 9. The device of claim 1, wherein the intermediate section has a length between about 6 mm and about 10 mm. 10. The device of claim 1, wherein the first configuration forms a cylindrical shape and the second configuration forms a planar shape, and wherein the cylindrical shape has an inner surface and an outer surface, and each of the inner surface and the outer surface of the cylindrical shape define a respective opposing proximal and distal side of the planar shape in the second configuration. 11. The device of claim 1, wherein the distal section has a smallest inner cross-sectional dimension in the second configuration that is less than a smallest inner cross-sectional dimension of the proximal section. 12. The device of claim 1, wherein, while transitioning from the first configuration to the second configuration, the distal end moves to an axial location aligned with the coupling. 13. The device of claim 1, wherein, while transitioning from the first configuration to the second configuration, the proximal end moves to an axial location aligned with the coupling. 14. The device of claim 1, wherein the distal section pivots about the coupling when transitioning from the first configuration to the second configuration. 15. The device of claim 1, wherein, while transitioning from the first configuration to the second configuration, (i) the distal end of the distal section is configured to move radially inwardly and proximally relative to the coupling and (ii) the proximal end of the distal section is configured to move radially outwardly and distally relative to the coupling. 16. The device of claim 15, wherein, while transitioning from the first configuration to the second configuration, the proximal end moves radially outwardly to define, in the second configuration, an outermost cross-sectional dimension that is greater than an outermost cross-sectional dimension of the proximal section. 17. The device of claim 15, wherein, while transitioning from the first configuration to the second configuration, the distal end moves radially inwardly to define, in the second configuration, an innermost cross-sectional dimension that is less than an innermost cross-sectional dimension of the proximal section. 18. The device of claim 15, wherein, when transitioned from the first configuration to the second configuration, the distal end defines a first lumen sized smaller than a second lumen defined by the proximal section. 19. The device of claim 15, wherein the distal section pivots about the coupling when transitioning from the first configuration to the second configuration. 20. The device of claim 1, wherein the undulating filaments are woven. 21. The device of claim 1, wherein the proximal section and the distal section are integrally cut from a tube or a sheet. 22. The device of claim 1, wherein the proximal section and the distal section are comprised of the same material. 23. The device of claim 1, wherein the distal section comprises a covering.
연구과제 타임라인
LOADING...
LOADING...
LOADING...
LOADING...
LOADING...
이 특허에 인용된 특허 (104)
Horton Joseph A. (Charleston SC), Anatomically shaped vasoocclusive device and method of making the same.
Schmid, Eric V.; Morris, Andrew; Nguyen, John; Eisele, Robert F; Howard, Steven C; Padilla, Orlando M; Simpson, Philip J, Balloon expandable crush-recoverable stent device.
McGurk Erin (Palo Alto CA) Dieck Ronald (Palo Alto CA) Tremulis William S. (Redwood City CA), Embolic elements and methods and apparatus for their delivery.
Bahler, Clinton D.; DeBruyne, Michael P.; Fearnot, Neal E.; Leewood, Alan R.; Mead, Jason A.; Osborne, Thomas A.; Sun, Jichao; Ninan, Lal, Endoluminal device with extracellular matrix material and methods.
Guglielmi Guido (Los Angeles CA) Sepetka Ivan (Redwood City CA), Endovascular electrolytically detachable guidewire tip for the electroformation of thrombus in arteries, veins, aneurysm.
Chin Yem ; McCrory Jennifer J. ; Tremaglio ; Jr. Anthony R. ; Guterman Lee R. ; Dassa Alyssa ; Hudson Richard, Removable occlusion system for aneurysm neck.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.