|국가/구분||United States(US) Patent 등록|
|국제특허분류(IPC7판)||C07K-016/00 A61K-039/395 A61K-039/40 C07K-016/24 C07K-001/00 A61K-039/00|
|발명자 / 주소|
|출원인 / 주소|
|대리인 / 주소||
|인용정보||피인용 횟수 : 0 인용 특허 : 1|
Bispecific antibodies are provided that specifically bind both Tumor Necrosis Factor alpha (TNFα) and Interleukin-17 (IL-17). The bispecific antibodies of the invention are useful for treating various autoimmune diseases, including Rheumatoid Arthritis (RA), Psoriatic Arthritis (PsA), and Ankylosing Spondylitis (AS).
1. An anti-TNF-anti-IL-17 bispecific antibody comprising a first polypeptide and a second polypeptide, wherein the first polypeptide has amino acid sequence of SEQ ID NO: 1, and the second polypeptide has an amino acid sequence of SEQ ID NO: 2. 2. The bispecific antibody of claim 1 comprising two first polypeptides and two second polypeptides. 3. A method of treating rheumatoid arthritis, psoriatic arthritis, or ankylosing spondylitis comprising administering to a patient in need thereof a therapeutically effective amount of a bispecific antibody of clai...