The present invention relates to a polyurethane polymer prepared from a mixture comprising: (a) at least one polyol of formula (I), wherein at least three of X1, X2, X3, X4 and X5 are each independently an OH-terminated polyoxyalkylene group, and the remainder of X1, X2, X3. X4 and X5 are each indep
The present invention relates to a polyurethane polymer prepared from a mixture comprising: (a) at least one polyol of formula (I), wherein at least three of X1, X2, X3, X4 and X5 are each independently an OH-terminated polyoxyalkylene group, and the remainder of X1, X2, X3. X4 and X5 are each independently H or absent, and Z is a central linking unit; (b) at least one di- or poly-isocyanate; and (c) optionally at least one OH-terminated chain extender. Further aspects of the invention relate to a process for preparing a polyurethane, and to a process for preparing a contact lens.
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1. A contact lens prepared by i. reacting a mixture comprising: (a) 30 to 70 wt % of at least one polyol of formula I, wherein at least three of X1, X2, X3, X4 and X5 are each independently an OH-terminated polyoxyalkylene group, and the remainder of X1, X2, X3, X4 and X5 are each independently H or
1. A contact lens prepared by i. reacting a mixture comprising: (a) 30 to 70 wt % of at least one polyol of formula I, wherein at least three of X1, X2, X3, X4 and X5 are each independently an OH-terminated polyoxyalkylene group, and the remainder of X1, X2, X3, X4 and X5 are each independently H or absent, and Z is a central linking unit;(b) a polydialkyl siloxane diol;(c) 9 to 50 wt % of at least one di- or poly-isocyanate; and(d) 10 to 25 wt % of at least one OH-terminated chain extender comprising two hydroxyl groups, having a molecular weight of 1000 or less;wherein the mixture comprises less than 0.3 wt % water;(ii) curing the mixture formed in step (i) directly to form a polyurethane xerogel; and(iii) hydrating the xerogel using an aqueous medium to form a hydrogel. 2. A contact lens according to claim 1 wherein the polyol is a macropolyol of formula Ia, wherein each of X1, X2 and X3 is independently an OH-terminated polyoxyalkylene group, wherein each polyoxyalkylene group is a polymer and/or copolymer of ethylene oxide and propylene oxide;and X4 is H or as defined for X1, X2 and X3. 3. A contact lens according to claim 1 wherein the polyol is a macropolyol of formula Ib, wherein each p is independently from about 3 to about 25; and each of R′ and R″ is independently H or alkyl. 4. A contact lens according to claim 1 wherein the polyol is a macropolyol of formula Ic, wherein Y is the group —CH2—CH(R′)—O—, R′ is H or CH3, n is an integer from 0 to 20, m is an integer from 0 to 6, k is an integer from 3 to 25 and each of q, r, s and t is independently an integer from 1 to 25. 5. A contact lens according to claim 1 wherein the polyol comprises silicon. 6. A contact lens according to claim 1 wherein the macropolyol has a molecular weight of from about 500 to about 20,000. 7. A contact lens according claim 1 wherein the di- or poly-isocyanate is selected from methylene bis (4-cyclohexyl isocyanate), 2,4,6-toluene triisocyanate, trifunctional trimer (isocyanurate) of isophorone diisocyanate, trifunctional trimer (isocyanurate) of hexamethylene diisocyanate and polymeric 4,4′diphenylmethane diisocyanate, methylene dicyclohexyl diisocyanate, hexamethylene diisocyanate, isophorone diisocyanate, toluene-2,4-diisocyanates, toluene-2,6-diisocyanate, mixtures of toluene-2,4 and 2,6-diisocyanates, ethylene diisocyanate, ethylidene diisocyanate, propylene-1,2-diisocyanate, cyclohexylene-1,2-diisocyanate, cyclohexylene-1,4-diisocyanate, m-phenylene diisocyanate, 3,3″-diphenylene-4,4″-biphenylene diisocyanate, 4,4″-biphenylene diisocyanate, 1,6-hexamethylene diisocyanate, 1,4-tetramethylene diisocyanate, 1,10-decamethylene diisocyanate, cumene-2,4-diisocyanate, 1,5-naphthalene diisocyanate, 1,4-cyclohexylene diisocyanate, 2,5-fluorenediisocyanate and polymeric 4,4′diphenylmethane diisocyanate. 8. A contact lens according to claim 1 wherein the chain extender is selected from polyethylene glycols and/or polypropylene glycols or glycols comprising copolymers of ethylene oxide and propylene oxide, triethylene glycol, 1,4-butanediol, tetraethylene glycol, diethylene glycol, ethylene glycol, hexanediol, propylene glycol, 2-ethylhexanediol-1,6, neopentyl glycol hydroquinone bis(2-hydroxyethyl) ether, dipropylene glycol, 2-methyl-2-ethyl-1,3-propanediol, 2-ethyl-1,3-hexanediol, 1,5-pentanediol, thiodiglycol, 1,3-propanediol, 1,3-butanediol, 2,3-butanediol, 1,2-dimethyl-1,2-cyclopentanediol, 1,2-cyclohexanediol, 1,2-dimethyl-1,2-cyclohexanediol, glycerol, trimethylol propane, trimethylol ethane, 1,2,6-hexanetriol, anhydroaneaheptitol, mannitol, sortbitol, methylglucoside and bis-1,4(β-hydroxyethoxy)benzene. 9. A contact lens according to claim 1 wherein the mixture further comprises a catalyst. 10. A contact lens according to claim 9 wherein the catalyst is a transition metal catalyst, an amine or a polyamine. 11. A contact lens according to claim 10 wherein the catalyst is selected from tributyltin dilaurate, FeCl3, stannous octoate, and triethylamine. 12. A contact lens according to claim 1 wherein the mixture further comprises one or more antioxidants. 13. A contact lens according to claim 12 wherein the mixture comprises 1 to 3 wt % antioxidant. 14. A contact lens according to claim 1 wherein the mixture further comprises one or more tinting agents. 15. A contact lens according to claim 1 wherein the mixture further comprises one or more UV blockers. 16. A contact lens according to claim 1 wherein the mixture further comprises one or more of a modulus modifier, a plasticizer, a humectant and a lubricant. 17. A contact lens according to claim 16 wherein the modulus modifier is poly(ethylene glycol) dimethyl ether. 18. A contact lens according to claim 1 wherein the polydialkyl siloxane diol is of formula V, wherein R is alkyl, p is an integer from 1 to 46 and x is an integer from 1 to 324. 19. A contact lens according to claim 18 wherein the polydialkyl siloxane diol of formula V is prepared by reacting a polydialkyl siloxane dihydride terminated of formula III with an allyl polyglycol of formula IV: 20. A contact lens according to claim 1 wherein the polydialkyl siloxane diol has the structure of Formula VI: wherein R is a small alkyl group, Y is an alkyl group, p is an integer from 1 to 110, x is an integer from 1 to 324, and A is an integer from 1 to 25. 21. An article of manufacture comprising a contact lens according to claim 1.
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