초록 ▼

An integrated passive wireless chip diagnostic sensor system is described that can be interrogated remotely with a wireless device such as a modified cell phone incorporating multi-protocol RFID reader capabilities (such as the emerging Gen-2 standard) or Bluetooth, providing universal easy to use,

An integrated passive wireless chip diagnostic sensor system is described that can be interrogated remotely with a wireless device such as a modified cell phone incorporating multi-protocol RFID reader capabilities (such as the emerging Gen-2 standard) or Bluetooth, providing universal easy to use, low cost and immediate quantitative analyses, geolocation and sensor networking capabilities to users of the technology. The present invention can be integrated into various diagnostic platforms and is applicable for use with low power sensors such as thin films, MEMS, electrochemical, thermal, resistive, nano or microfluidic sensor technologies. Applications of the present invention include on-the-spot medical and self-diagnostics on smart skin patches, Point-of-Care (POC) analyses, food diagnostics, pathogen detection, disease-specific wireless biomarker detection, remote structural stresses detection and sensor networks for industrial or Homeland Security using low cost wireless devices such as modified cell phones.

대표청구항 ▼

1. A Lab-on-a-Chip microfluidics sensor system for use in conducting rapid diagnostic measurements comprising: a Lab-On-A-Chip (LOC) microfluidics sensor test strip comprising a substrate containing a plurality of wells and a plurality of microfluidics channels, said channels permitting a flow of fl

1. A Lab-on-a-Chip microfluidics sensor system for use in conducting rapid diagnostic measurements comprising: a Lab-On-A-Chip (LOC) microfluidics sensor test strip comprising a substrate containing a plurality of wells and a plurality of microfluidics channels, said channels permitting a flow of fluids between said wells;a radio frequency identification (RFID) tag comprising an antenna, a unique identification number, and an RFID electronic chip in combination with at least one sensor module and both integrated with said substrate, with a plurality of conductive leads connecting said RFID electronic chip and said sensor module to said wells and said channels, and said RFID tag and said sensor module combination configured to sense, control and transmit wirelessly signals that correspond to reactions occurring in said wells and to transmit wirelessly said unique identification number;a wireless reader configured to communicate wirelessly with said RFID tag and said sensor module combination through the use of multiple protocols and to receive said signals that correspond to said reactions occurring in said wells and said unique identification number, said wireless reader configured to control a flow of fluids through said microfluidics channels and to and from said wells by sending signals to said REID tag and said sensor module combination wirelessly; andsaid wireless reader further configured to communicate wirelessly over a network through the use of multiple communication protocols to download software wirelessly from a remote location to enable reading and analysis of said signals received from said RFID tag and said sensor module combination based on said unique identification number of said RFID tag and sensor module combination. 2. A Lab-on-a-Chip microfluidics sensor system as set forth in claim 1, wherein said wireless reader is a cellular telephone. 3. A Lab-on-a-Chip microfluidics sensor system as set forth in claim 1, wherein said RFID electronic chip includes a temperature sensor. 4. A Lab-on-a-Chip microfluidics sensor system as set forth in claim 1, wherein said LOC microfluidics sensor test strip is disposable. 5. A Lab-on-a-Chip microfluidics sensor system as set forth in claim 1, wherein at least one of said wells is an input well for receiving a fluid for analysis. 6. A Lab-on-a-Chip microfluidics sensor system as set forth in claim 1, wherein at least one of said wells is a test well for receiving a fluid for analysis. 7. A Lab-on-a-Chip microfluidics sensor system as set forth in claim 1, wherein at least one of said wells is a chemical well for containing at least one chemical used in a reaction conducted on said LOC microfluidics sensor test strip. 8. A Lab-on-a-Chip microfluidics sensor system as set forth in claim 1, wherein said LOC microofluidics sensor test strip is configured to perform quantitative protein measurements and said reaction includes a quantitative determination of protein in a test sample in at least one of said wells. 9. A Lab-on-a-Chip microfluidics sensor system as set forth in claim 1, wherein said LOC microfluidics sensor test strip is configured to perform quantitative biomarker measurements and said reaction includes a quantitative determination of at least one biomarker in a test sample in at least one of said wells. 10. A Lab-on-a-Chip microfluidics sensor system as set forth in claim 1, wherein said LOC microfluidics sensor test strip is configured to perform DNA tests on a sample and said reaction includes performing a DNA test on a sample in at least one of said wells. 11. A Lab-on-a-hip microfluidics sensor system as set forth in claim 1, wherein said RFID electronic chip communicates with said wireless reader to provide power to said wells and to said microfluidics channels. 12. A Lab-on-a-Chip microfluidics sensor system as set forth in claim 1, wherein said RFID electronic chip is selected from the group consisting of an RFID chip, a Bluetooth chip, a Zigbee chip, and an IEEE 1073 chip. 13. A Lab-on-a-Chip microfluidics sensor system as set forth in claim 1, wherein said multiple communication protocols include Bluetooth, Wi-Fi, Broadband, WLAN, air 3G communication protocols. 14. A Lab-on-a-Chip microfluidics sensor system as set forth in claim 1, wherein said reaction is mixing of a sample in a well. 15. A Lab-on-a-Chip microfluidics sensor system as set forth in claim 1, wherein at least one of said LOC microfluidics sensor test strip or said wireless reader is further configured to be geolocated by one of a global positioning system or a non-global positioning system by triangulation means. 16. A Lab-on-a-Chip microfluidics sensor system as set forth in claim 1, wherein said wireless reader is further configured to communicate over a network through the use of multiple protocols and to upload said signals received from said RFID to and said sensor module for analysis in a location other than a location of said wireless reader. 17. A Lab-on-a-Chip microfluidics sensor system as set forth in claim 1, further including a light emitting diode (LED) electronic measuring device on said sensor test strip.