Methods compositions, and kit for whitening hyper pigmented spots on skin
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61Q-019/02
A61K-008/89
A61K-008/58
A61K-008/81
출원번호
US-0308406
(2014-06-18)
등록번호
US-9474705
(2016-10-25)
발명자
/ 주소
Mu, Weilin
Castro, John R.
출원인 / 주소
ELC Management LLC
대리인 / 주소
Blackburn, Julie
인용정보
피인용 횟수 :
2인용 특허 :
16
초록▼
A skin whitening composition comprising a liquid polymeric coating material that, upon exposure to ambient air and moisture in skin, hardens to a water resistant, water vapor permeable, adherent and conformable solid film when applied to skin, and at least one skin whitening active; and a method and
A skin whitening composition comprising a liquid polymeric coating material that, upon exposure to ambient air and moisture in skin, hardens to a water resistant, water vapor permeable, adherent and conformable solid film when applied to skin, and at least one skin whitening active; and a method and kit for whitening skin.
대표청구항▼
1. A method for whitening discrete hyper pigmented spots on skin by applying to the discrete spots in need of whitening and not to the surrounding non-hyper-pigmented skin a liquid pigmented treatment composition comprising at least one skin whitening active in a polymeric coating material comprisin
1. A method for whitening discrete hyper pigmented spots on skin by applying to the discrete spots in need of whitening and not to the surrounding non-hyper-pigmented skin a liquid pigmented treatment composition comprising at least one skin whitening active in a polymeric coating material comprising 1-35% dimethicone silylate; from 1-50% of a volatile solvent selected from the group consisting of isododecane, dimethicone and mixtures thereof; from 1-50% of a non-volatile silicone oil having a viscosity of 20 to 200,000 cst at room temperature; from about 0.1 to 40% of a silicone surfactant; from about 0.1 to 15% of a quaternized montmorillonite mineral; and from 0.5 to 65% titanium dioxide in combination with pigments that, upon exposure to ambient air and moisture in skin, hardens to a water resistant, water vapor permeable, conformable solid film that colors the spots so they are shade matched with the surrounding non-hyperpigmented skin and remains unchanged in adherence and color to the spots for 24 hours after application and is thereafter applied to the spots every 12 to 72 hours to color the spots to shade match them to the surrounding untreated skin while whitening the treated spots over time while the pigmentation of the untreated surrounding non-hyperpigmented spots remains unchanged. 2. The method of claim 1 wherein the treatment composition is re-applied after the first application for a time sufficient to cause the discrete hyper-pigmented spots to whiten to match the untreated surrounding non-hyperpigmented skin. 3. The method of claim 2 wherein the treatment composition is applied for 4 to 60 days. 4. A method for whitening discrete hyper pigmented spots on skin by applying to the discrete spots in need of whitening and not to the surrounding non-hyper-pigmented skin, a treatment composition comprising a skin whitening active in a liquid polymeric coating comprising dimethicone silylate, isododecane, dimethicone, phenyl trimethicone, dimethicone copolyol, a quaternized montmorillonite mineral, polymethylmethacrylate, and titanium dioxide containing pigments, that, upon exposure to ambient air and moisture in skin hardens to a water resistant, water vapor permeable, adherent, conformable solid film that colors the spot to shade match the surrounding untreated non-hyperpigmented skin wherein the adherence of the treatment composition to the spots remains unchanged for 24 hours and the treatment composition is re-applied every 12 to 72 hours thereafter for a time sufficient to cause the treated discrete hyper-pigmented spots to match the surrounding non-hyperpigmented skin and whiten the spots over time while the untreated surrounding non-hyperpigmented skin remains unchanged. 5. The method of claim 4 wherein the treatment composition is applied every 12 to 72 hours for a period of 4 to 60 days. 6. A kit for whitening discrete hyper pigmented spots on the hands comprising: a receptacle having a closure with a cap and extending rod having affixed at the distal end a deformable pinpoint applicator with an application surface of a size that permits application of a treatment composition to discrete hyperpigmented spots on the hands and not surrounding non-hyperpigmented skin, and stored within the receptacle a treatment composition comprising at least one skin whitening active in a polymeric coating material comprising 1-35% dimethicone silylate; from 1-50% of a volatile solvent selected from the group consisting of isododecane, dimethicone and mixtures thereof; from 1-50% of a non-volatile silicone oil having a viscosity of 20 to 200,000 cst at room temperature; from about 0.1 to 40% of a silicone surfactant: from about 0.1 to 15% of a quaternized montmorillonite mineral; and from 0.5 to 65% titanium dioxide in combination with pigments that, upon exposure to ambient air and moisture in skin, hardens to a water resistant, water vapor permeable, adherent and conformable solid film that colors the spot so they are shade matched with the surrounding non-hyperpigmented skin; wherein the adherence and color of the treatment composition to the spots on the hands remains unchanged for one day after application. 7. The kit of claim 6 wherein the applicator is a brush. 8. The kit of claim 6 wherein the pinpoint applicator is made from silicone or a thermoplastic material selected from the group consisting of polyurethane, polyethylene, or polypropylene. 9. The kit of claim 6 wherein the pinpoint applicator is made from thermoplastic polyurethane. 10. The kit of claim 9 wherein the pinpoint applicator is deformable. 11. The kit of claim 9 wherein the pinpoint applicator is flocked. 12. The kit of claim 6 wherein the applicator has an application surface from 5 to 25 millimeters in diameter.
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