Fluidic structures for membraneless particle separation
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
B03B-005/62
B03B-005/32
B03B-013/00
B04C-001/00
B04C-011/00
B01D-021/26
출원번호
US-0120093
(2008-05-13)
등록번호
US-9486812
(2016-11-08)
발명자
/ 주소
Lean, Meng H.
Seo, Jeonggi
Kole, Ashutosh
Volkel, Armin R.
출원인 / 주소
Palo Alto Research Center Incorporated
대리인 / 주소
Fay Sharpe LLP
인용정보
피인용 횟수 :
2인용 특허 :
63
초록▼
Fluidic structures for facilitating particle separation in curved or spiral devices are provided. The contemplated systems relate to various fluidic structures, implementations and selected fabrication techniques to realize construction of fluidic separation structures that are of a stacked and/or p
Fluidic structures for facilitating particle separation in curved or spiral devices are provided. The contemplated systems relate to various fluidic structures, implementations and selected fabrication techniques to realize construction of fluidic separation structures that are of a stacked and/or parallel configuration. These contemplated systems provide for efficient input of fluid to be processed, improved throughput, and, in some variations, adjustable and efficient treatment of output fluid.
대표청구항▼
1. A particle separation system comprising: a plurality of individual curved particle separation devices, each particle separation device being planar and having a curved channel, stacked such that the devices are parallel to one another;an inlet coupler connected to all inlets of the devices, the i
1. A particle separation system comprising: a plurality of individual curved particle separation devices, each particle separation device being planar and having a curved channel, stacked such that the devices are parallel to one another;an inlet coupler connected to all inlets of the devices, the inlet coupler being operative to facilitate input of fluid to all inlets of the plurality of individual curved particle separation devices;at least two outlet couplers connected to the corresponding outlets of the plurality of individual curved particle separation devices, wherein each particle separation device achieves separation between outlet couplers based on flow driven forces generated by fluid flow in curved channels of the curved particle separation devices, the flow driven forces including centrifugal forces and at least flow pressure forces or buoyancy forces; and,a controller configured to control the separation devices based on at least one of pressure, bandwidth, flow rate, temperature and viscosity. 2. The system as set forth in claim 1 wherein the curved particle separation devices are spiral devices. 3. The system as set forth in claim 1 wherein the curved particle separation devices comprise curved portions that span between 180 degrees and 360 degrees of angular distance along a diameter thereof. 4. The system as set forth in claim 1 further comprising a feedback system. 5. The system as set forth in claim 4 wherein the feedback system feeds data relating to at least one of pressure, flow rate, bandwidth, viscosity, and temperature to the controller. 6. The system as set forth in claim 1 further comprising at least a second plurality of stacked curved particle separation devices arranged in parallel with the plurality of stacked curved particle separation devices. 7. A particle separation system comprising: an inlet manifold;a plurality of separation channels facilitating fluid flow therein and arranged in a helical spiral configuration wherein the channels are parallel to one another, wherein each separation channel achieves separation for the fluid flow based on flow driven forces generated by the fluid flow in the channel, the flow driven forces including centrifugal forces and at least flow pressure forces or buoyancy forces;an output manifold wherein the output manifold includes a portion therein operative to split the fluid flow from each of the channels and wherein the portion is a static collar portion; and,a controller configured to control the separation channels based on at least one of pressure, bandwidth, flow rate, temperature and viscosity. 8. A particle separation system comprising: an inlet manifold;a plurality of separation channels facilitating fluid flow therein and arranged in a helical spiral configuration wherein the channels are parallel to one another, wherein each separation channel achieves separation for the fluid flow based on flow driven forces generated by the fluid flow in the channel, the flow driven forces including centrifugal forces and at least flow pressure forces or buoyancy forces;an output manifold wherein the output manifold includes a portion therein operative to split the fluid flow from each of the channels and wherein the portion is a substantially circular collar portion; and,a controller configured to control the separation channels based on at least one of pressure, bandwidth, flow rate, temperature and viscosity. 9. A particle separation system comprising: an inlet manifold;a plurality of separation channels facilitating fluid flow therein and arranged in a helical spiral configuration wherein the channels are parallel to one another, wherein each separation channel achieves separation for the fluid flow based on flow driven forces generated by the fluid flow in the channel, the flow driven forces including centrifugal forces and at least flow pressure forces or buoyancy forces;an output manifold wherein the output manifold includes a portion therein operative to split the fluid flow from each of the channels and wherein the portion is comprised of curves to provide a continuously adjustable split of the fluid flow; and,a controller configured to control the separation channels based on at least one of pressure, bandwidth, flow rate, temperature and viscosity. 10. A particle separation system comprising: an inlet manifold;a plurality of separation channels facilitating fluid flow therein and arranged in a helical spiral configuration wherein the channels are parallel to one another, wherein each separation channel achieves separation for the fluid flow based on flow driven forces generated by the fluid flow in the channel, the flow driven forces including centrifugal forces and at least flow pressure forces or buoyancy forces;an output manifold wherein the output manifold includes a portion therein operative to split the fluid flow from each of the channels and wherein the portion is comprised of discrete step segments to provide a step-wise adjustable split of the fluid flow; and,a controller configured to control the separation channels based on at least one of pressure, bandwidth, flow rate, temperature and viscosity. 11. A particle separation system comprising: an inlet manifold;a plurality of separation channels facilitating fluid flow therein and arranged in a helical spiral configuration wherein the channels are parallel to one another, wherein the plurality of separation channels is arranged in a first stage and a second stage, wherein the first stage and second stage are separated by a fluid inverter and wherein each separation channel achieves separation for the fluid flow based on flow driven forces generated by the fluid flow in the channel, the flow driven forces including centrifugal forces and at least flow pressure forces or buoyancy forces;an output manifold wherein the output manifold includes a portion therein operative to split the fluid flow from each of the channels; and,a controller configured to control the separation channels based on at least one of pressure, bandwidth, flow rate, temperature and viscosity. 12. A particle separation system comprising: receiving fluid having particles distributed therein through an inlet coupler connected to all inlets of a plurality of individual curved particle separation devices stacked such that the devices are parallel to one another;separating the particles in each individual curved particle separation device into a first portion or band of the fluid having selected particles therein and a second portion of the fluid without such particles, the separation being achieved based on flow driven forces generated by fluid flow in curved channels of the individual curved particle separation devices, the flow driven forces including centrifugal forces and at least flow pressure forces or buoyancy forces;controlling the separation devices based on at least one of pressure, bandwidth, flow rate, temperature and viscosity; and, outputting the first portions or bands of the fluid as a particulate stream and the second portion of the fluid as an effluent stream through corresponding outlet couplers connected to the corresponding outlets of each of the plurality of individual curved particle separation devices. 13. The method as set forth in claim 12 further comprising measuring at least one of the pressure, the flow rate, the bandwidth, the viscosity, and the temperature of the fluid flow and controlling the separation devices by modifying the fluid flow based on the measuring. 14. The system as set forth in claim 1 wherein each channel is enclosed or sealed. 15. A particle separation system comprising: a stack of individual curved particle separation devices, each particle separation device being planar and having a curved channel;an inlet coupler connected to all inlets of the devices, the inlet coupler being operative to facilitate input of fluid to all inlets of the plurality of individual curved particle separation devices;at least two outlet couplers connected to the corresponding outlets of the plurality of individual curved particle separation devices, wherein each particle separation device achieves separation between outlet couplers based on flow driven forces generated by fluid flow in curved channels of the curved particle separation devices, the flow driven forces including centrifugal forces and at least flow pressure forces or buoyancy forces; and,a controller configured to control the separation devices based on at least one of pressure, bandwidth, flow rate, temperature and viscosity. 16. The system as set forth in claim 15 wherein each channel is enclosed or sealed. 17. The system as set forth in claim 15 wherein the particle separation devices are stacked in a parallel configuration. 18. The system as set forth in claim 15 wherein the curved particle separation devices are spiral devices. 19. The system as set forth in claim 15 wherein the curved particle separation devices comprise curved portions that span between 180 degrees and 360 degrees of angular distance along a diameter thereof. 20. The system as set forth in claim 15 further comprising a feedback system. 21. The system as set forth in claim 20 wherein the feedback system feeds data relating to at least one of pressure, flow rate, bandwidth, viscosity, and temperature to the controller. 22. The system as set forth in claim 15 further comprising at least a second plurality of stacked curved particle separation devices arranged in parallel with the plurality of stacked curved particle separation devices. 23. The system as set forth in claim 7 further comprising a feedback system. 24. The system as set forth in claim 8 further comprising a feedback system. 25. The system as set forth in claim 9 further comprising a feedback system. 26. The system as set forth in claim 10 further comprising a feedback system. 27. The system as set forth in claim 11 further comprising a feedback system.
연구과제 타임라인
LOADING...
LOADING...
LOADING...
LOADING...
LOADING...
이 특허에 인용된 특허 (63)
Yager Paul ; Brody James P., Absorption-enhanced differential extraction device.
Mller Friedrich E. (Eisdorf DEX) Oesterwind G. Wolfgang (Osterode DEX) Nothdurft Jrgen (Clausthal-Zellerfeld DEX), Centrifugal-chamber separating apparatus.
V?lkel,Armin R.; Lean,Meng H.; Hsieh,Huangpin Ben; Daniel,Jurgen, Concentration and focusing of bio-agents and micron-sized particles using traveling wave grids.
Ashmead James William (Middletown DE) Blaisdell Charles Thomas (Middletown DE) Johnson Melvin Harry (Chadds Ford PA) Nyquist Jack Kent (Chadds Ford PA) Perrotto Joseph Anthony (Landenberg PA) Ryley ;, Integrated chemical processing apparatus and processes for the preparation thereof.
Giddings John C. (Salt Lake City UT), Method and apparatus for hydrodynamic relaxation and sample concentration NIN field-flow fraction using permeable wall e.
Schlichter Stefan,DEX ; Kramer Thomas,DEX, Method and apparatus for recognizing foreign substances in and separating them from a pneumatically conveyed fiber stream.
Rumpf Hans (Hansjakobstr. 12 7500 Karlsruhe DEX) Maly Karl (Bachstrasse 46 7500 Karlsruhe DEX) Leschonski Kurt (Am Dammgraben 20 3392 Clausthal-Zellerfeld DEX), Method and apparatus for the continuous centrifugal classifying of a continuous flow of particulate material in a deflec.
Bernhard H. Weigl ; Paul Yager ; James P. Brody ; Mark R. Holl ; Fred K. Forster ; Eric Altendorf ; Paul C. Galambos ; Margaret Kenny ; David Schutte ; Gregory Hixson ; Diane Zebert ; Andr, Microfabricated devices and methods.
Heller Michael J. (Encinitas CA) Tu Eugene (San Diego CA) Butler William F. (Carlsbad CA), Molecular biological diagnostic systems including electrodes.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.