Antioxidant dietary supplement and related method
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61K-036/53
A61K-036/906
A61K-036/73
A61K-036/9066
A61K-036/31
A23L-001/30
A23L-002/52
A61K-031/352
A61K-045/06
출원번호
US-0088765
(2013-11-25)
등록번호
US-9517249
(2016-12-13)
발명자
/ 주소
Fast, David J.
Patterson, Jennifer
Rajgopal, Arun
Pusateri, Donald J.
Gellenbeck, Kevin W.
Scholten, Jeffrey
Missler, Steven R.
Randolph, Russell K.
Chuang, Jennifer
Lin, Yumei
Kazlova, Valiantsina
출원인 / 주소
Access Business Group International LLC
대리인 / 주소
Warner Norcross & Judd LLP
인용정보
피인용 횟수 :
1인용 특허 :
28
초록▼
A supplement including a blend of turmeric, quercetin and rosemary, or holy basil, wasabi, and broccoli seed extract which are present in a balanced and predetermined ratio, and which stimulate the Antioxidant Response Element (ARE), Quinone Reductase, and/or induce related gene expression, for exam
A supplement including a blend of turmeric, quercetin and rosemary, or holy basil, wasabi, and broccoli seed extract which are present in a balanced and predetermined ratio, and which stimulate the Antioxidant Response Element (ARE), Quinone Reductase, and/or induce related gene expression, for example, heme oxygenase-1 (HMOX-1) expression. The blend of ingredients can be formed as or in a dietary supplement adapted for administration to a subject. The dietary supplement can be formulated so that the turmeric, quercetin and rosemary are present in a predetermined ratio of 1:3:5, or holy basil, wasabi, and broccoli seed extract in a predetermined ratio of 1:1:0.2. Additional ingredients can be included in the supplement. The supplement can synergistically affect natural antioxidant response pathways within cells of a subject to whom the supplement is administered. A related method of use is also provided.
대표청구항▼
1. A method for stimulating an antioxidant response element (ARE) and/or inducing Heme Oxygenase-1 (HOX-1) expression in the cells of a human in need thereof, comprising orally administering to said human an effective amount of a dietary supplement comprising turmeric, quercetin and rosemary, wherei
1. A method for stimulating an antioxidant response element (ARE) and/or inducing Heme Oxygenase-1 (HOX-1) expression in the cells of a human in need thereof, comprising orally administering to said human an effective amount of a dietary supplement comprising turmeric, quercetin and rosemary, wherein the turmeric, quercetin and rosemary are present in the supplement in a ratio of 1:3:5, respectively. 2. The method of claim 1 wherein the orally administering step includes administering to the human the dietary supplement in the form of at least one of a capsule, tablet, and liquid form. 3. The method of claim 1 wherein turmeric in an amount of 33 mg, quercetin in an amount of 100 mg, and rosemary in an amount of 167 mg, are administered during the orally administering step. 4. The method of claim 1 wherein turmeric in an amount of 66 mg, quercetin in an amount of 200 mg, and rosemary in an amount of 333 mg, are administered during the orally administering step. 5. The method of claim 1 further comprising orally administering at least one of vitamins and minerals with the dietary supplement to the human. 6. The method of claim 1, wherein said orally administering to said human also decreases urinary level of 8-isoprostane and/or blood serum level of catalase in the human. 7. The method of claim 1, wherein said orally administering to said human also increases production of at least one of glutathione peroxidase and superoxide dismutase in the human. 8. The method of claim 1 wherein the turmeric is at least one of derived and extracted from Curcuma longa. 9. The method of claim 1 wherein the quercetin is at least one of derived and extracted from at least one of apples, onions, parsley, sage, tea, blueberries, blackberries, bilberries, Fava d'anta and Sophora japonica. 10. The method of claim 1 wherein the rosemary is at least one of derived and extracted from Rosmarinus officinalis.
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이 특허에 인용된 특허 (28)
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Daniel O. Lukaczer ; Gary K. Darland ; DeAnn J. Liska ; Tracey A. Irving ; Jeffrey S. Bland, Dietary supplements for treating fatigue-related syndromes.
Fast, David J.; Patterson, Jennifer; Rajgopal, Arun; Pusateri, Donald J.; Gellenbeck, Kevin W.; Scholten, Jeffrey; Missler, Stephen R.; Randolph, Russell K.; Chuang, Jennifer; Lin, Yumei; Kazlova, Valiantsina, Antioxidant dietary supplement and related method.
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