최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
DataON 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Edison 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
---|---|
국제특허분류(IPC7판) |
|
출원번호 | US-0341468 (2014-07-25) |
등록번호 | US-9532741 (2017-01-03) |
발명자 / 주소 |
|
출원인 / 주소 |
|
대리인 / 주소 |
|
인용정보 | 피인용 횟수 : 0 인용 특허 : 400 |
The present invention provides a biointerface membrane for use with an implantable device that interferes with the formation of a barrier cell layer including; a first domain distal to the implantable device wherein the first domain supports tissue attachment and interferes with barrier cell layer f
The present invention provides a biointerface membrane for use with an implantable device that interferes with the formation of a barrier cell layer including; a first domain distal to the implantable device wherein the first domain supports tissue attachment and interferes with barrier cell layer formation and a second domain proximal to the implantable device wherein the second domain is resistant to cellular attachment and is impermeable to cells. In addition, the present invention provides sensors including the biointerface membrane, implantable devices including these sensors or biointerface membranes, and methods of monitoring glucose levels in a host utilizing the analyte detection implantable device of the invention. Other implantable devices which include the biointerface membrane of the present invention, such as devices for cell transplantation, drug delivery devices, and electrical signal delivery or measuring devices are also provided.
1. An implantable device for continuous measurement of a glucose concentration, comprising: a sensing region configured to continuously measure a signal indicative of a glucose concentration in a host; anda membrane located over the sensing region, wherein the membrane comprises a first layer and a
1. An implantable device for continuous measurement of a glucose concentration, comprising: a sensing region configured to continuously measure a signal indicative of a glucose concentration in a host; anda membrane located over the sensing region, wherein the membrane comprises a first layer and a second layer, wherein the first layer comprises an enzyme configured to catalyze a reaction with glucose as a reactant, wherein the second layer is formed of a blend comprising a polyurethane polymer and an acrylate polymer. 2. The implantable device of claim 1, wherein the polyurethane polymer is a copolymer, wherein the copolymer comprises silicone. 3. The implantable device of claim 1, wherein the acrylate polymer comprise methacrylate. 4. The implantable device of claim 1, wherein the membrane is configured to facilitate obtaining of a level of accuracy corresponding to having, over a period of time exceeding 5 days, 90% of measured analyte values within an “A” region and a “B” region of a standard Clarke error grid when sensor measurements are compared to a standard reference measurement. 5. The implantable device of claim 1, wherein the membrane has a thickness of from about 10 microns to about 100 microns. 6. The implantable device of claim 1, wherein the membrane is configured to provide an interface with an interstitial fluid. 7. The implantable device of claim 1, wherein the membrane is configured to prevent barrier cell formation.
Copyright KISTI. All Rights Reserved.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.