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A medical apparatus and method of preparing one or more cell blocks. The medical apparatus comprises at least one elongate tubular body having a proximal end and a distal end and a filter membrane disposed between the proximal end and a distal end of the elongate tubular body. The filter membrane, w

A medical apparatus and method of preparing one or more cell blocks. The medical apparatus comprises at least one elongate tubular body having a proximal end and a distal end and a filter membrane disposed between the proximal end and a distal end of the elongate tubular body. The filter membrane, which can include alignment features and structural features to engage the tubular body, and/or cover, is sectionable. Additionally, in some embodiments a second elongate tubular body is provided which telescopingly receives at least a portion of the first elongate tubular body. In other embodiments, a support member is provided for engaging the filter membrane and positioning the filter membrane at a midpoint of the elongate tubular body during centrifuging.

대표청구항 ▼

1. A medical apparatus comprising: a first elongate tubular body member having a proximal end and a distal end defining an interior space therebetween, and means for engaging a filter member assembly unit,a filter assembly unit comprising a bottom surface including a porous membrane and a base membe

1. A medical apparatus comprising: a first elongate tubular body member having a proximal end and a distal end defining an interior space therebetween, and means for engaging a filter member assembly unit,a filter assembly unit comprising a bottom surface including a porous membrane and a base member having a body circumferentially surrounding the porous membrane and having upwardly extending sidewalls such that the bottom surface and upwardly extending sidewalls define a receptacle for collecting a biological sample, the filter assembly unit further including a structural reinforcement member for removably attaching to the engaging means of the first elongate tubular body member,wherein the base member consists essentially of paraffin material and the entire filter assembly unit is sliceable into sections suitable for mounting on a slide for microscopy. 2. The medical apparatus of claim 1, wherein the filter assembly unit is engaged to the distal end of the first elongate tubular body member. 3. The medical apparatus of claim 1, wherein the means for physically engaging the filter member assembly unit includes a platform disposed at the distal end of the first elongate body member. 4. The medical apparatus of claim 1, wherein the structural reinforcement member removably attaches the filter assembly between the proximal and distal ends of the first elongate tubular body. 5. The medical apparatus of claim 1, wherein the structural reinforcement member includes a protrusion configured to engage a shelf extending from a surface of the first elongate tubular body. 6. The medical apparatus of claim 1, wherein the filter assembly includes a plurality of peaks and valleys extending around at least a portion of its circumference. 7. The medical apparatus of claim 1, wherein the porous membrane is centrally disposed in the receptacle. 8. The medical apparatus of claim 1, wherein the filter assembly includes recesses distributed about the base member. 9. The medical apparatus of claim 1, wherein the filter assembly includes indicia for orientation of a collected biological sample. 10. The medical apparatus of claim 1, further comprising a second elongate tubular body sized to receive at least a portion of the first elongate tubular body. 11. The medical apparatus of claim 10, wherein the first elongate tubular member includes a platform to attach to the filter assembly and a circumscribing shelf for attaching the first elongate tubular body to the second elongate tubular member. 12. The medical apparatus of claim 1, further comprising a cover pivotably connected to the distal end of the first elongate tubular member. 13. The medical apparatus of claim 1, wherein the proximal end of the first elongate tubular body is open and the apparatus further includes a lid sized to close an opening at the proximal end of the elongate tubular member, the lid formed of material capable of self-sealing after puncture by a needle. 14. A medical apparatus comprising: a first elongate tubular body member having a proximal end and a distal end defining an interior space therebetween, and means for engaging a filter member assembly unit;a second elongate tubular body member having a proximal end and a distal end defining an interior space therebetween sized to receive the first elongate tubular body, anda filter assembly comprising a unitary body having a bottom surface and upwardly extending sidewalls to define a receptacle suitable to hold a biological sample, and a structural reinforcement member for removably attaching the filter assembly to the engaging means of the first elongate tubular member,wherein the upwardly extending sidewalls consist essentially of paraffin material and the assembly is sliceable into sections suitable for mounting on a slide. 15. The medical apparatus of claim 14, wherein the receptacle contains a cell block. 16. The medical apparatus of claim 15, wherein the entire filter assembly is sliceable without contaminating the cell block. 17. The medical apparatus of claim 14, wherein the structural reinforcement member includes threads to engage the distal end of the first elongate tubular member. 18. The medical apparatus of claim 14, wherein the structural reinforcement member includes a protrusion to engage the distal end of the first elongate tubular member. 19. The medical apparatus of claim 14, wherein the structural reinforcement member engages a shelf disposed in the first elongate tubular body. 20. A filter assembly for preparing cells block comprising: a unitary body including a non-porous base member having an upwardly extending wall bordering a membrane having pores between about 0.4 μm to about 5 μm, the base member and porous membrane defining a receptacle suitable for collecting and processing a biological sample into a cell block, the unitary body further including at least one structural reinforcement member such that the filter assembly can removably attach to a tubular body member,wherein the non-porous base member consists essentially of paraffin material and the filter assembly sliceable into sections suitable for mounting on a slide for microscopy while holding a cell block. 21. The filter assembly of claim 20, wherein the filter assembly has an outer surface including alternating peaks and valleys around the periphery of the unitary body. 22. The filter assembly of claim 20, wherein the filter assembly further includes a compressive cover for enclosing the receptacle defined by the base member and porous membrane. 23. The filter assembly of claim 22, further including a cell block disposed in the receptacle. 24. The filter assembly of claim 20, wherein the filter assembly is engaged to an elongate tubular body member. 25. The filter assembly of claim 24, wherein the engaged elongate tubular body member and filter assembly are disposed within a centrifuge tube. 26. The medical apparatus of claim 14, wherein the first elongate tubular body member is engaged to the filter assembly, and further wherein the first elongate tubular body member and engaged filter assembly is disposed within the second tubular body member.