[특허]Tamper resistant pharmaceutical formulations

Tamper resistant pharmaceutical formulations 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	A61K-009/24 A61K-047/36 A61K-009/20 A61K-031/485 A61K-031/165 A61K-031/167 A61K-047/02 A61K-047/32 A61K-031/5375 A61K-031/74 A61K-031/715 A61K-031/78 A61K-031/717
출원번호	US-0670651 (2015-03-27)
등록번호	US-9545448 (2017-01-17)
발명자 / 주소	Guido, Debora Huang, Haiyong Hugh
출원인 / 주소	Purdue Pharma L.P.
대리인 / 주소	Lowenstein Sandler LLP
인용정보	피인용 횟수 : 0 인용 특허 : 176

초록

Disclosed in certain embodiments is a solid oral dosage form comprising a heat-labile gelling agent; a thermal stabilizer; and a drug susceptible to abuse.

대표청구항 ▼

1. A method for treating pain comprising administering to a patient in need thereof, a solid oral dosage form wherein the solid oral dosage form comprises: a heat-labile gelling agent;a thermal stabilizer; andan opioid agonist, wherein the solid oral dosage form releases at least about 85% of the opioid agonist within 45 minutes as measured by in-vitro dissolution in a USP Apparatus 2 (paddle) at 50 rpm in 500 ml SGF at 37° C. 2. The method of claim 1, wherein the opioid agonist is oxycodone or a pharmaceutically acceptable salt thereof. 3. The method of claim 1, wherein the heat-labile gelling agent is a polymer. 4. The method of claim 3, wherein the polymer is a polysaccharide. 5. The method of claim 4, wherein the polysaccharide is a microbial polysaccharide. 6. The method of claim 5, wherein the microbial polysaccharide is xanthan gum. 7. The method of claim 1, wherein the thermal stabilizer is a gelling agent different than the heat labile gelling agent. 8. The method of claim 7, wherein the thermal stabilizer gelling agent is a polymer. 9. The method of claim 8, wherein the thermal stabilizer gelling agent polymer is an anionic polymer in a neutral pH aqueous solution. 10. The method of claim 9, wherein the anionic polymer is a polyacrylic acid. 11. The method of claim 10, wherein the polyacrylic acid is a carbomer homopolymer. 12. The method of claim 1, wherein the heat-labile gelling agent is xanthan gum and the thermal stabilizer is carbomer homopolymer. 13. The method of claim 1, wherein the ratio of the heat-labile gelling agent to the thermal stabilizer is from about 1:5 to about 5:1 (w/w). 14. The method of claim 1, wherein the ratio of the heat-labile gelling agent to the thermal stabilizer is from about 1:1 to about 1:5 (w/w). 15. The method of claim 1, wherein the ratio of the opioid agonist to the heat-labile gelling agent is from about 1:40 to about 40:1 (w/w). 16. The method of claim 1, wherein the ratio of the opioid agonist to heat-labile gelling agent is from about 1:20 to about 20:1 (w/w). 17. The method of claim 1, further comprising an irritant. 18. The method of claim 17, wherein the irritant is a surfactant, capsaicin or a capsaicin analog. 19. The method of claim 18, wherein the surfactant is selected from the group consisting of a poloxamer, a sorbitan monoester, a glyceryl monooleate, sodium lauryl sulfate and mixtures thereof.

이 특허에 인용된 특허 (176)

Khanna Ish K. (Vernon Hills IL) Weier Richard M. (Lake Bluff IL) Collins Paul W. (Deerfield IL) Yu Yi (Skokie IL) Xu Xiangdong (Evanston IL) Partis Richard A. (Evanston IL) Koszyk Francis J. (Prospec, 1,2-aryl and heteroaryl substituted imidazolyl compounds for the treatment of inflammation.
상세보기
Black Cameron (Pointe Claire CAX) Mancini Joseph A. (St. Leonard CAX) Lau Cheuk K. (Ile Bizard CAX) Prasit Petpiboon (Kirkland CAX) Vickers Philip J. (Pierrefonds CAX 4), 1-aroyl-3-indolyl alkanoic acids and derivatives thereof useful as anti-inflammatory agents.
상세보기
Guay Daniel (Ile Perrot CAX) Li Chun-Sing (Dollard des Ormeaux CAX), 5-methanesulfonamido-1-indanones as an inhibitor of cyclooxygenase-2.
상세보기
Anderson, Carter R.; Morris, Russell L., Abuse potential reduction in abusable substance dosage form.
상세보기
Bastin Richard James,GBX ; Lithgow Bruce Hamilton,GBX, Abuse resistant tablets.
상세보기
Hirsh,Jane; Kibanov,Alexander M.; Swager,Timothy M.; Buchwald,Stephen L.; Lo,Whe Yong; Fleming,Alison B.; Rariy,Roman V., Abuse-deterrent pharmaceutical compositions of opiods and other drugs.
상세보기
Arkenau-Maric, Elisabeth; Bartholomaus, Johannes; Kugelmann, Heinrich, Abuse-proof dosage form.
상세보기
Arkenau-Maric, Elisabeth; Bartholomäus, Johannes; Kugelmann, Heinrich, Abuse-proofed dosage form.
상세보기
Bartholomaus, Johannes; Kugelmann, Heinrich; Arkenau-Marić, Elisabeth, Abuse-proofed dosage form.
상세보기
Bartholomäus, Johannes; Kugelmann, Heinrich; Arkenau-Marić, Elisabeth, Abuse-proofed dosage form.
상세보기
Bartholomäus, Johannes; Kugelmann, Heinrich, Abuse-proofed dosage system.
상세보기
Black W. Cameron (Pointe-Claire CAX) Li Chun-Sing (Dollard Des Ormeaux CAX) Guay Daniel (Notre Dame de L\lle Perrot CAX) Prasit Petpiboon (Kirkland CAX) Roy Patrick (Dollard Des Ormeaux CAX), Alkanesulfonamido-1-indanone derivatives as inhibitors of cyclooxygenase.
상세보기
Burch, Ronald M.; Sackler, Richard S.; Goldenheim, Paul D., Analgesic combination of oxycodone and meloxicam.
상세보기
Burch, Ronald M.; Sackler, Richard S; Goldenheim, Paul D, Analgesic combination of oxycodone and nimesulide.
상세보기
Caruso Frank S., Analgesic drug composition containing a capsaicinoid and potentiator therefor.
상세보기
Guimberteau, Florence; Dargelas, Frédéric, Anti-misuse microparticulate oral pharmaceutical form.
상세보기
Saunders Richard J. (San Jose CA) Mefferd Wayne Sherman (Los Altos Hills CA), Apparatus for tracking moving workpiece by a laser beam.
상세보기
Oshlack Benjamin (New York NY) Chasin Mark (Manalapan NJ) McGinity James (Austin TX) Bodmeier Roland (Austin TX), Aqueous dispersions of zein and preparation thereof.
상세보기
Gauthier Jacques Y. (Laval CAX) Lau Cheuk K. (Ile Bizard CAX) LeBlanc Yves (Kirkland CAX) Li Chun-Sing (Dollard des Ormeaux CAX) Roy Patrick (Dollard des Ormeaux CAX) Therien Michel (Laval CAX) Wang , Aryl substituted 5,5 fused aromatic nitrogen compounds as anti-inflammatory agents.
상세보기
Keith Alec D. (Boalsburg PA) Snipes Wallace C. (Pine Grove Mills PA), Buccal drug dosage form.
상세보기
Reid Derek J. (London GB3) Walpole Christopher S. J. (London GB3) Wrigglesworth Roger (Kemsing GB3), Capsaicin derivatives.
상세보기
Chenevier, Phillippe; Marechal, Dominique, Coated particles with prolonged release and tablets containing same.
상세보기
Hamann Scott R., Combined antagonist compositions.
상세보기
Joaquina Faour AR, Combined diffusion/osmotic pumping drug delivery system.
상세보기
Kuczynski Anthony L. ; Childers Jerry D. ; Barclay Glen E. ; Rodriguez Susan ; Merrill Sonya, Composition and dosage form comprising opioid antagonist.
상세보기
Porter Garry L. (Wichita KS), Composition and method of immobilizing emetics and method of treating human beings with emetics.
상세보기
Porter Garry L. (507 N. Volutsia Wichita KS 67214), Composition and method to prevent accidental and intentional overdosage with psychoactive drugs.
상세보기
Blumberg Peter M. (Frederick MD), Composition of resiniferatoxin and analogues thereof to cause sensory afferent C-Fiber and thermoregulatory desensitizat.
상세보기
Drust Eugene G. (Norwich NY) Kasting Gerald B. (Wyoming OH) Smith Ronald L. (West Chester OH) Szkutak Joan B. (West Chester OH), Compositions for the transdermal delivery of pharmaceutical actives.
상세보기
Akireddy, Srinivasa Rao; Bhatti, Balwinder Singh; Cuthbertson, Timothy J.; Miller, Craig Harrison; Mitchener, Jr., Joseph Pike, Compounds.
상세보기
Oshlack Benjamin (New York NY), Controlled release bases for pharmaceuticals.
상세보기
Oshlack Benjamin (New York NY), Controlled release bases for pharmaceuticals.
상세보기
Oshlack Benjamin (New York NY) McGinity James (Austin TX) Chasin Mark (Manalapan NJ) Bodmeier Roland (Austin TX), Controlled release coatings derived from aqueous dispersions of zein.
상세보기
Leslie Stewart T. (Aberdeen GB6), Controlled release compositions.
상세보기
Miller Ronald Brown,CHX ; Leslie Stewart Thomas,GB2 ; Prater Derek Allan,GB2 ; Knott Trevor John,GB2 ; Mohammad Hassan,GB2, Controlled release diamorphine formulation.
상세보기
Goldie Robert S. (Cambridge GB2) Malkowska Sandra T. A. (Cambridge GB2) Leslie Stewart T. (Cambridge GB2) Miller Ronald B. (Basel CHX), Controlled release dihydrocodeine composition.
상세보기
Frisbee, Steven, Controlled release dosage forms.
상세보기
DeCrosta Mark T. (Plainsboro NJ) Jain Nemichand B. (Monmouth Junction NJ) Rudnic Edward M. (Kendall Park NJ), Controlled release formulation.
상세보기
Jain Nemichand B. (Monmouth Junction NJ) Gertie Linda P. (Cinnaminson NJ) Rudnic Edward M. (Plainsboro NJ), Controlled release formulation.
상세보기
Chen Chih-Ming (Davie FL) Lee Der-Yang (Plantation FL) Xie Jianbo (Davie FL) Rodriguez Aurelio (Hialeah FL), Controlled release formulation having a preformed passageway.
상세보기
Ludwig Nelson H. (Greenfield IN) Ose Earl E. (Greenfield IN), Controlled release formulations and method of treatment.
상세보기
Oshlack Benjamin (New York NY) Chasin Mark (Manalapan NJ) Pedi ; Jr. Frank (Yorktown Heights NY), Controlled release formulations coated with aqueous dispersions of acrylic polymers.
상세보기
Oshlack Benjamin (New York NY) Pedi ; Jr. Frank (Yorktown Heights NY) Chasin Mark (Manalapan NJ), Controlled release formulations coated with aqueous dispersions of acrylic polymers.
상세보기
Oshlack, Benjamin; Huang, Hua-Pin; Masselink, John K.; Tonelli, Alfred, Controlled release hydrocodone.
상세보기
Oshlack, Benjamin; Huang, Hua-Pin; Masselink, John K.; Tonelli, Alfred P., Controlled release hydrocodone formulations.
상세보기
Oshlack, Benjamin; Huang, Hua-Pin; Masselink, John; Tonelli, Alfred P., Controlled release hydrocodone formulations.
상세보기
Oshlack, Benjamin; Masselink, John K.; Huang, Hua-Pin; Tonelli, Alfred P., Controlled release hydrocodone formulations.
상세보기
Goldie Robert S. (Comberton GB2) Malkowska Sandra T. A. (Landbeach GB2) Leslie Stewart T. (Cambridge GB2) Miller Ronald B. (Basel CHX), Controlled release hydromorphone composition.
상세보기
Goldie Robert S. (Comberton GBX) Malkowska Sandra T. A. (Landbeach GBX) Leslie Stewart T. (Cambridge GBX) Miller Ronald B. (Basel CHX), Controlled release hydromorphone composition.
상세보기
Krishnamurthy Thinnayam N. (Ontario CAX), Controlled release matrix suppository for pharmaceuticals.
상세보기
Oshlack Benjamin (New York NY) Chasin Mark (Manalpan NJ) Minogue John J. (Mount Vernon NY) Kaiko Robert F. (Weston CT), Controlled release oxycodone compositions.
상세보기
Oshlack Benjamin (New York NY) Chasin Mark (Manalpan NJ) Minogue John J. (Mount Vernon NY) Kaiko Robert F. (Weston CT), Controlled release oxycodone compositions.
상세보기
Oshlack Benjamin (New York NY) Chasin Mark (Manalpan NJ) Minogue John Joseph (Mount Vernon NY) Kaiko Robert Francis (Weston CT), Controlled release oxycodone compositions.
상세보기
Oshlack Benjamin (New York NY) Minogue John J. (Mount Vernon NY) Chasin Mark (Manalpan NJ), Controlled release oxycodone compositions.
상세보기
Dandiker Yogendra (Ware GB3) Huckle Paul D. (Ware GB3), Controlled release pharmaceutical compositions.
상세보기
Tijsma,Edze Jan; Terlingen,Johannes Gijsbertus Antonius; Haas Schrijen,Saskia; Vriesema,Hein Herman, Controlled release products and processes for the preparation thereof.
상세보기
Oshlack Benjamin (New York NY) Chasin Mark (Manalpan NJ) Pedi ; Jr. Frank (Yorktown Heights NY), Controlled-release formulations coated with aqueous dispersions of ethylcellulose.
상세보기
Swanson, Jon; Jain, Rajeev A.; Hontz, Robert; Devane, John G.; Cumming, Kenneth Iain; Clancy, Maurice Joseph Anthony; Codd, Janet Elizabeth; Liversidge, Gary, Controlled-release nanoparticulate compositions.
상세보기
Friend David R. ; Wong David, Delivery of drugs to the lower GI tract.
상세보기
Blum Melvin ; Roitberg Michael, Denatonium capsaicinate and methods of producing the same.
상세보기
Prasit Petpiboon (Kirkland CAX) Guay Daniel (Iie Perrot CAX) Wang Zhaoyin (Pierrefonds CAX) Leger Serge (Dollar des Ormeaux CAX) Therien Michel (Laval CAX), Diaryl bicyclic heterocycles as inhibitors of cyclooxygenase-2.
상세보기
Bjork, Anders K. K.; Olsson, Knut G.; Abramo, Aina L.; Christensson, Erik G., Diphenylbutyl-piperazinecarboxamides in pharmaceutical compositions and methods.
상세보기
Shukla Atul J. (Memphis TN) Vattanasiri Anumontri (Bangkok PA THX) Nambiar Jyothi S. (Pittsburgh PA), Directly compressible granules having improved flow properties.
상세보기
Royce Alan E. (Effort PA), Directly compressible polyethylene oxide vehicle for preparing therapeutic dosage forms.
상세보기
Bernardin Didier (60 Rue de Varenne 75007 Paris FRX), Display tray for aligned articles.
상세보기
Sawada, Toyohiro; Sako, Kazuhiro; Yoshioka, Tatsunobu; Watanabe, Shunsuke, Drug delivery system for averting pharmacokinetic drug interaction and method thereof.
상세보기
Huang, Haiyong Hugh, Encased tamper resistant controlled release dosage forms.
상세보기
Hoffmeister ; Friedrich ; Hiltmann ; Rudolf ; Wollweber ; Hartmund ; Kr amer ; Helmut, Enteral pharmaceutical compositions.
상세보기
Oshlack Benjamin (New York NY) Leslie Stewart T. (Aberdeen GB6), Extended action controlled release compositions.
상세보기
Edgren David E. ; Li Shu ; Bhatti Gurdish Kaur ; Wong Patrick S. L. ; Skluzacek Robert R., Extended release dosage form.
상세보기
Kumar, Vijai; Dixon, David; Tewari, Divya; Wadgaonkar, Dilip B., Extended release opioid abuse deterrent compositions and methods of making same.
상세보기
Oshlack Benjamin ; Chasin Mark ; Huang Hua-Pin, Extruded multi-particulates.
상세보기
Oshlack Benjamin ; Chasin Mark ; Huang Hua-Pin, Extruded orally administrable opioid formulations.
상세보기
Han, Chien-Hsuan; Hou, Sui Yuen Eddie; Reid, Monica L., Gastric retentive extended-release dosage forms comprising combinations of a non-opioid analgesic and an opioid analgesic.
상세보기
Weber Eckard (Laguna Beach CA) Keana John F. W. (Eugene OR), Glycine receptor antagonists and the use thereof.
상세보기
Bola Tarlok S. (Ilford GB2), Granular pharmaceutical formulations.
상세보기
James W. McGinity ; Feng Zhang, Hot-melt extrudable pharmaceutical formulation.
상세보기
Merrill Sonya ; Ayer Atul D. ; Chadha Navjot ; Kuczynski Anthony L., Hydromorphone therapy.
상세보기
LaHann Thomas R. (Cleves OH) Buckwalter Brian L. (Yardley PA), Hydroxyphenylacetamides having analgesic and anti-irritant activity.
상세보기
Oshlack Benjamin (New York NY) Chasin Mark (Manalapan NJ), Immediate release tablet cores of insoluble drugs having sustained-release coating.
상세보기
Oshlack Benjamin ; Chasin Mark, Immediate release tablet cores of insoluble drugs having sustained-release coating.
상세보기
Mayer, David J.; Price, Donald D.; Mao, Jianren; Lyle, John W., Inhibiting the development of tolerance to and/or dependence on a narcotic addictive substance.
상세보기
Mayer David J. (Richmond VA) Price Donald D. (Richmond VA) Mao Jianren (Richmond VA) Lyle John W. (Belmar NJ), Inhibiting the development of tolerance to and/or dependence on an addictive substance.
상세보기
Carroll, F. Ivy; Thomas, James B.; Mascarella, S. Wayne, Kappa opioid receptor ligands.
상세보기
Byas-Smith Michael G., Method and compositions for controlling oral and pharyngeal pain using capsaicinoids.
상세보기
Horhota Stephen T. ; Saim Said, Method for extraction and reaction using supercritical fluids.
상세보기
Mayer David J. (Richmond VA) Price Donald D. (Richmond VA) Mao Jianren (Richmond VA) Lyle John W. (Belmar NJ), Method for the treatment of pain.
상세보기
Miller Ronald Brown,CHX ; Leslie Stewart Thomas,GB2 ; Malkowska Sandra Therese Antoinette,GB2 ; Prater Derek Allan,GB2 ; Knott Treavor John,GB2 ; Heafield Joanne,GB2 ; Challis Deborah,GB2, Method of preparing sustained release pharmaceutical compositions.
상세보기
Palermo Philip J. ; Colucci Robert D. ; Kaiko Robert F., Method of preventing abuse of opioid dosage forms.
상세보기
Palermo, Philip J.; Kaiko, Robert F.; Colucci, Robert D., Method of preventing abuse of opioid dosage forms.
상세보기
Crain Stanley M. (Leonia NJ) Shen Ke-fei (Flushing NY), Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by morphine and other o.
상세보기
Sackler Richard ; Kaiko Robert ; Goldenheim Paul, Method of treating humans with opioid formulations having extended controlled release.
상세보기
Sackler Richard S. (Greenwich CT) Kaiko Robert F. (Weston CT) Goldenheim Paul (Wilton CT), Method of treating pain by administering 24 hour oral opioid formulations.
상세보기
Sackler Richard (Greenwich CT) Goldenheim Paul (Wilton CT) Kaiko Robert (Weston CT), Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasm.
상세보기
Kreek Mary J. (New York NY), Method of treating patients suffering from chronic pain or chronic cough.
상세보기
Kreek Mary J. (New York NY) Fishman Jack (New York NY), Method of treating patients suffering from chronic pain or chronic cough.
상세보기
Kumar,Vijai; Dixon,David; Tewari,Divya; Wadgaonkar,Dilip B., Methods and compositions for deterring abuse of opioid containing dosage forms.
상세보기
Busetti Cesare,ITX ; Crimella Tiziano,ITX, Methods for treating early morning pathologies.
상세보기
Busetti,Cesare; Crimella,Tiziano, Methods for treating early morning pathologies.
상세보기
Barrett R. Cooper, Methods for treating opiate intolerance.
상세보기
Granger Colin D. (Chester NJ) Simon Thomas H. (Morris Plains NJ), Misuse-resistive transdermal opioid dosage form.
상세보기
Bhatt, Padmanabh P.; Kidane, Argaw; Edwards, Kevin, Modified release preparations containing oxcarbazepine and derivatives thereof.
상세보기
Fischer, Gina; Bar-Shalom, Daniel; Slot, Lillian; Andersen, Christine, Morphine polymer release system.
상세보기
Merrill Sonya (San Jose CA) Ayer Atul D. (Palo Alto CA) Hwang Paul (Campbell CA) Kuczynski Anthony L. (Mt. View CA), Morphine therapy.
상세보기
Merrill Sonya (San Jose CA) Ayer Atul Devdatt (Palo Alto CA) Hwang Paul (Campbell CA) Kuczynski Anthony L. (Mt. View CA), Morphine therapy.
상세보기
Colombo Paolo (Milan ITX) Cardona Antonio C. (Milan ITX) Pifferi Giorgio (Milan ITX), Multilayer matrix systems for the controlled release of active principles.
상세보기
Lau Cheuk Kun (Ile Bizard CAX) Black Cameron (Pointe Claire CAX) Guay Daniel (Ile Perrot CAX) Gauthier Jacques-Yves (Laval CAX) LeBlanc Yves (Kirkland CAX) Roy Patrick (Dollard des Ormeaux CAX) Ducha, N-benzyl indol-3-yl butanoic acid derivatives as cyclooxygenase inhibitors.
상세보기
Lau Cheuk K. (Ile Bizard CAX) Black Cameron (Pointe Claire CAX) Belley Michel (Pierrefonds CAX), N-benzyl-3-indoleacetic acids as antiinflammatory drugs.
상세보기
Lau Cheuk K. (Ile Bizard CAX) Black Cameron (Pointe Claire CAX) Guay Daniel (Ile Perrot CAX) Gauthier Jacques Y. (Laval CAX) LeBlanc Yves (Kirkland CAX) Roy Patrick (Dollard des Ormeaux CAX) Ducharme, N-benzylindol-3-yl propanoic acid derivatives as cyclooxygenase inhibitors.
상세보기
Houn Simon Hsia ; David Fan, Nutritive composition for cardiovascular health containing fish oil, garlic, rutin, capsaicin, selenium, vitamins and juice concentrates.
상세보기
Chen Chih-Ming ; Chou Joseph C. H., Once daily pharmaceutical tablet having a unitary core.
상세보기
Chih-Ming Chen ; Joseph C. H. Chou, Once daily pharmaceutical tablet having a unitary core.
상세보기
Leys Cassius W. (Hartsdale NY) Walsh ; III Edward (Valley Cottage NY), One coat protective system for a surface.
상세보기
Robert F. Kaiko ; Robert D. Colucci, Opioid agonist/opioid antagonist/acetaminophen combinations.
상세보기
Chasin Mark ; Oshlack Benjamin ; Pedi ; Jr. Frank, Opioid formulations having extended controlled released.
상세보기
Gusler, Gloria; Berner, Bret; Chau, Mei; Padua, Aimee, Optimal polymer mixtures for gastric retentive tablets.
상세보기
Muggetti,Lorena; Martini,Alessandro; Civaroli,Paola; James,Christopher, Oral formulations for anti-tumor compounds.
상세보기
Shaw Irving F. (East Rockaway NY) Berk Jerome (New Rochelle NY), Orally administered drug composition for therapy in the treatment of narcotic drug addiction.
상세보기
Oshlack Benjamin ; Chasin Mark, Orally administrable opioid formulations having extended duration of effect.
상세보기
Oshlack, Benjamin; Chasin, Mark, Orally administrable opioid formulations having extended duration of effect.
상세보기
Wong Patrick S. L. (Hayward CA) Barclay Brian L. (Sunnyvale CA) Deters Joseph C. (Mt. View CA) Theeuwes Felix (Los Altos CA), Osmotic device for administering certain drugs.
상세보기
Wong Patrick S. L. (Hayward CA) Barclay Brian (Sunnyvale CA) Deters Joseph C. (Mt. View CA) Theeuwes Felix (Los Altos CA), Osmotic device with dual thermodynamic activity.
상세보기
Joaquina Faour AR; Marcelo A. Coppari AR, Osmotic device within an osmotic device.
상세보기
Ayer Atul D. (Mountain View CA) Theeuwes Felix (Los Altos CA), Osmotic system with distribution zone for dispensing beneficial agent.
상세보기
Guillaumet Grald (Orleans FRX) Flouzat Christine (Clermont Ferrand FRX) Devissaguet Michelle (Neuilly sur Seine FRX) Renard Pierre (Versailles FRX) Caignard Daniel H. (Paris FRX) Adam Grard (le Mesni, Oxazolopyridine compounds, compositions and use.
상세보기
Fukunaga Atsuo F. (5411 Littlebow Rd. Rancho Palos Verdes CA 90274) Funuknaga Alex S. (5411 Littlebow Rd. Rancho Palos Verdes CA 90274), Pharmaceutical compositions including mixtures of an adenosine compound and a catecholamine.
상세보기
Kelm Gary Robert ; Manring Gary Lee, Pharmaceutical dosage form for colonic delivery.
상세보기
Wright, Curtis; Oshlack, Benjamin; Breder, Christopher, Pharmaceutical formulation containing gelling agent.
상세보기
Oshlack, Benjamin; Wright, Curtis; Breder, Christopher, Pharmaceutical formulation containing opioid agonist, opioid antagonist and gelling agent.
상세보기
Miller Ronald Brown,CHX ; Leslie Stewart Thomas,GB2 ; Malkowska Sandra Therese Antoinette,GB2 ; Knott Treavor John,GB2 ; Challis Deborah,GB2 ; Prater Derek Allan,GB2 ; Heafield Joanne,GB2, Pharmaceutical multiparticulates.
상세보기
Hidaka Osafumi (Akigawa JPX) Murakami Satoshi (Tachikawa JPX), Pharmaceutical plasters.
상세보기
Brand Larry M. (West Chester OH), Pharmaceutical products providing enhanced analgesia.
상세보기
LaHann Thomas R. (Cleves OH), Pharmaceutical products providing enhanced analgesia.
상세보기
Ducharme Yves (Montreal CAX) Gauthier Jacques Y. (Laval CAX) Prasit Petpiboon (Kirkland CAX) Leblanc Yves (Kirkland CAX) Wang Zhaoyin (Pierrefond CAX) Leger Serge (Dollard des Omeaux CAX) Therien Mic, Phenyl heterocycles as COX-2 inhibitors.
상세보기
Ducharme Yves (Montreal CAX) Gauthier Jacques Y. (Laval CAX) Prasit Petpiboon (Kirkland CAX) Leblanc Yves (Kirkland CAX) Wang Zhaoyin (Pierrefond CAX) Leger Serge (Dollard Des Ormeaux CAX) Therien Mi, Phenyl heterocycles as cox-2 inhibitors.
상세보기
Ducharme Yves (Montreal CAX) Gauthier Jacques Y. (Laval CAX) Prasit Petpiboon (Kirkland CAX) Leblanc Yves (Kirkland CAX) Wang Zhaoyin (Pierrefond CAX) Leger Serge (Dollard Des Ormeaux CAX) Therien Mi, Phenyl heterocycles as cox-2 inhibitors.
상세보기
Oshlack Benjamin (New York NY) Pedi ; Jr. Frank (Yorktown Heights NY), Powder-layered morphine sulfate formulations.
상세보기
Klimesch Roger (Alsbach-Haehnlein DEX) Bleckmann Gerhard (Lampertheim DEX) Schlemmer Lothar (Maxdorf DEX), Preparation of pharmaceutical mixtures.
상세보기
Richard Ting ; Charles Hsiao, Press coated, pulsatile drug delivery system suitable for oral administration.
상세보기
Ting, Richard; Hsiao, Charles, Press coated, pulsatile drug delivery system suitable for oral administration.
상세보기
Gordon Maxwell (Syracuse NY) Pachter Irwin J. (Fayetteville NY), Prevention of analgesic abuse.
상세보기
Theeuwes ; Felix ; Saunders ; Richard J. ; Mefford ; Wayne S., Process for forming outlet passageways in pills using a laser.
상세보기
Ayer Atul D. (Mountain View CA) Theeuwes Felix (Los Altos CA), Process for manufacturing device with dispersion zone.
상세보기
Arkenau, Elisabeth; Bartholomāus, Johannes, Process for the production of an abuse-proofed solid dosage form.
상세보기
Batt Douglas G. (Wilmington DE) Pinto Donald J. P. (Newark DE) Orwat Michael J. (Wilmington DE) Petraitis Joseph J. (Glenmoore PA) Pitts William J. (Newark DE), Prostaglandin synthase inhibitors.
상세보기
Allen, Jennifer R.; Bourbeau, Matthew P.; Chen, Ning; Hu, Essa; Kunz, Roxanne, Pyrazine compounds as phosphodiesterase 10 inhibitors.
상세보기
Wolfgang A. Ritschel ; Mukul A. Agrawal, Self-destructing, controlled release peroral drug delivery system.
상세보기
Leslie Stewart T. (Aberdeen GB6), Slow release pharmaceutical compositions.
상세보기
Leslie Stewart Thomas (Aberdeen SC), Slow release pharmaceutical compositions.
상세보기
Oshlack Benjamin (New York NY) Chasin Mark (Manalapan NJ) Pedi ; Jr. Frank (Yorktown Heights NY), Stabilized controlled release formulations having acrylic polymer coating.
상세보기
Oshlack Benjamin (New York NY) Chasin Mark (Manalapan NJ) Pedi ; Jr. Frank (Yorktown Heights NY), Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer.
상세보기
Oshlack Benjamin (New York NY) Pedi ; Jr. Frank (Yorktown Heights NY) Chasin Mark (Manalapan NJ), Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer.
상세보기
Miller Ronald Brown,CHX ; Leslie Stewart Thomas,GBX ; Malkowska Sandra Therese Antoinette,GBX ; Prater Derek Allan,GBX ; Knott Trevor John,GBX ; Heafield Joanne,GBX ; Challis Deborah,GBX, Substained release compositions and a method of preparing pharmaceutical compositions.
상세보기
Miller Ronald Brown,CHX ; Leslie Stewart Thomas,GBX ; Malkowska Sandra Therese Antoinette,GBX ; Prater Derek Allan,GBX ; Knott Trevor John,GBX ; Heafield Joanne,GBX ; Challis Deborah,GBX, Sustained release compositions and a method of preparing pharmaceutical compositions.
상세보기
Heafield Joanne,GB2 ; Knott Trevor John,GB2 ; Leslie Stewart Thomas,GB2 ; Malkowska Sandra Therese Antoinette,GB2 ; Miller Ronald Brown,CHX ; Prater Derek Allan,GB2 ; Smith Kevin John,GB2, Sustained release compositions of morphine and a method of preparing pharmaceutical compositions.
상세보기
Zhang Guohua (Parsippany NJ) Pinnamaraju Prasad (Edison NJ), Sustained release formulation containing three different types of polymers.
상세보기
Davis, Robert D.; Blume, Ralph W.; Keyser, Donald Jeffrey, Sustained release formulations of guaifenesin and additional drug ingredients.
상세보기
Morella Angelo M. (Campbelltown AUX) Fisher Mark C. (Birkenhead AUX), Sustained release pharmaceutical composition.
상세보기
Morella Angelo M. (Campbelltown AUX) Fisher Mark C. (Birkenhead AUX), Sustained release pharmaceutical composition.
상세보기
Morella Angelo M. (Campbelltown AUX) Fisher Mark C. (Birkenhead AUX), Sustained release pharmaceutical composition.
상세보기
Hayashida Tomohiro (Chikujo-gun JPX) Kikumaru Kadoya (Chikujo-gun JPX) Tomoyuki Omura (Takatsuki JPX), Sustained release tablet.
상세보기
Schor Joseph M. (Locust Valley NY) Nigalaye Ashok (Jackson Heights NY) Gaylord Norman G. (New Providence NJ), Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose.
상세보기
Staniforth John N.,GB2 ; Sherwood Bob E. ; Hunter Edward A., Sustained-release formulations utilizing pharmaceutical excipient having improved compressibility.
상세보기
James S. Chu ; Yisong Yang ; Joseph A. Fix, Tablets and methods for modified release of hydrophilic and other active agents.
상세보기
Conte Ubaldo (Busto Arsizio ITX) La Manna Aldo (Pavia ITX) Colombo Paolo (Pavia ITX), Tablets with controlled-rate release of active substances.
상세보기
Guido, Debora; Huang, Haiyong Hugh, Tamper resistant pharmaceutical formulations.
상세보기
Oshlack, Benjamin; Wright, Curtis; Haddox, J. David, Tamper-resistant oral opioid agonist formulations.
상세보기
Ayer Atul D. (Mt. View CA) Theeuwes Felix (Los Altos CA), Therapeutic device for osmotically dosing at controlled rate.
상세보기
Galiatsatos Vassilios (Stow OH) Alabakovska Lubica (Cary NC), Time-release delivery matrix composition and corresponding controlled-release compositions.
상세보기
Chien Yie W. (North Brunswick NJ) Chiang Chin-Chih (Piscataway NJ) Tojo Kabuji (Highland Park NJ), Transdermal absorption dosage unit for narcotic analgesics and antagonists and process for administration.
상세보기
Sharma Kuldeepak (Mountain View CA) Roy Samir D. (Mountain View CA) Roos Eric J. (Redwood City CA), Transdermal administration of buprenorphine.
상세보기
Gale Robert M. (Los Altos CA) Goetz Victor (Palo Alto CA) Lee Eun S. (Redwood City CA) Taskovich Lina T. (Palo Alto CA) Yum Su I. (Los Altos CA), Transdermal administration of fentanyl and device therefor.
상세보기
Hille Thomas (Neuwied DEX) Deurer Lothar (Koblenz DEX) Hoffmann Hans-Rainer (Neuwied DEX), Transdermal therapeutic system comprising as active component buprenorphine.
상세보기
Gawin Frank H. (New Haven CT) Humblestone Brian G. (Nassau BSX) Allen David F. (Nassau BSX), Treating habit disorders.
상세보기
Gawin Frank H. (New Haven CT) Humblestone Brian G. (Nassau BSX) Allen David F. (Nassau BSX), Treating habit disorders.
상세보기
Dewey, Stephen L.; Brodie, Jonathan D.; Ashby, Jr., Charles R., Treatment of addiction and addiction-related behavior.
상세보기

IPC	Description
A	생활필수품
A62	인명구조; 소방(사다리 E06C)
A62B	인명구조용의 기구, 장치 또는 방법(특히 의료용에 사용되는 밸브 A61M 39/00; 특히 물에서 쓰이는 인명구조 장치 또는 방법 B63C 9/00; 잠수장비 B63C 11/00; 특히 항공기에 쓰는 것, 예. 낙하산, 투출좌석 B64D; 특히 광산에서 쓰이는 구조장치 E21F 11/00)
A62B-1/08	.. 윈치 또는 풀리에 제동기구가 있는 것

내보내기 구분	파일저장 인쇄 메일전송
구성항목	기본정보 상세정보 관리번호, 국가코드, 자료구분, 상태, 출원번호, 출원일자, 공개번호, 공개일자, 등록번호, 등록일자, 발명명칭(한글), 발명명칭(영문), 출원인(한글), 출원인(영문), 출원인코드, 대표IPC 관리번호, 국가코드, 자료구분, 상태, 출원번호, 출원일자, 공개번호, 공개일자, 공고번호, 공고일자, 등록번호, 등록일자, 발명명칭(한글), 발명명칭(영문), 출원인(한글), 출원인(영문), 출원인코드, 대표출원인, 출원인국적, 출원인주소, 발명자, 발명자E, 발명자코드, 발명자주소, 발명자 우편번호, 발명자국적, 대표IPC, IPC코드, 요약, 미국특허분류, 대리인주소, 대리인코드, 대리인(한글), 대리인(영문), 국제공개일자, 국제공개번호, 국제출원일자, 국제출원번호, 우선권, 우선권주장일, 우선권국가, 우선권출원번호, 원출원일자, 원출원번호, 지정국, Citing Patents, Cited Patents
저장형식	Text(ASCII format) Excel format PIAS분석(.xls)
메일정보	받는사람 (필수) @ 보내는사람 (선택) @ 제목 내용 KISTI 검색결과 이메일 서비스
안내	총 건의 자료가 검색되었습니다. 다운받으실 자료의 인덱스를 입력하세요. (1-10,000) 검색결과의 순서대로 최대 10,000건 까지 다운로드가 가능합니다. 데이타가 많을 경우 속도가 느려질 수 있습니다.(최대 2~3분 소요) 다운로드 파일은 UTF-8 형태로 저장됩니다. 파일의 내용이 제대로 보이지 않을실 때는 웹브라우저 상단의 보기 -> 인코딩 -> 자동선택 여부를 확인하십시오. ~ Text(ASCII format) Excel format

연합인증

Tamper resistant pharmaceutical formulations 원문보기

초록

대표청구항 ▼

연구과제 타임라인

이 특허에 인용된 특허 (176)

관련 콘텐츠

특허 원문 보기

IPC 상위 출원인

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

선택된 텍스트

연합인증

Tamper resistant pharmaceutical formulations 원문보기

초록

대표청구항 ▼

연구과제 타임라인

전체(0) 논문(0) 특허(0) 보고서(0)

전체(0) 논문(0) 특허(0) 보고서(0)

이 특허에 인용된 특허 (176)

관련 콘텐츠

특허 원문 보기

IPC 상위 출원인

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

선택된 텍스트