Exemplary embodiments provide a syringe plunger formed of a polymeric material. The syringe plunger includes a pressurizer disposed at a proximal end, and a distal end bifurcated into a first plunger arm having a first conical surface and a second conical surface, and a second plunger arm having a f
Exemplary embodiments provide a syringe plunger formed of a polymeric material. The syringe plunger includes a pressurizer disposed at a proximal end, and a distal end bifurcated into a first plunger arm having a first conical surface and a second conical surface, and a second plunger arm having a first conical surface and a second conical surface. The distal end includes a first contact surface defined by the first conical surface of the first plunger arm and the first conical surface of the second plunger arm, the first contact surface configured to initially contact a firing engagement mechanism, the first contact surface disposed at a first angle of between about 40° and about 80° relative to a longitudinal axis of the syringe plunger. The distal end also includes a second contact surface defined by the second conical surface of the first plunger arm and the second conical surface of the second plunger arm, the second contact surface configured to contact the firing engagement mechanism subsequent to contact by the first contact surface.
대표청구항▼
1. A syringe plunger formed of a polymeric material, the syringe plunger comprising: a pressurizer disposed at a first end; anda second bifurcated end having a first plunger arm with an end surface, a first transition edge defining an outer perimeter of the end surface of the first plunger arm, a se
1. A syringe plunger formed of a polymeric material, the syringe plunger comprising: a pressurizer disposed at a first end; anda second bifurcated end having a first plunger arm with an end surface, a first transition edge defining an outer perimeter of the end surface of the first plunger arm, a second transition edge, and a third transition edge; and a second plunger arm with an end surface, a first transition edge defining an outer perimeter of the end surface of the second plunger arm, a second transition edge, and a third transition edge, the second bifurcated end including: a first contact surface defined by a surface between the first transition edge of the first plunger arm and the second transition edge of the first plunger arm and a surface between the first transition edge of the second plunger arm and the second transition edge of the second plunger arm, the first contact surface configured to initially contact a firing engagement mechanism;a second contact surface defined by a surface between the second transition edge of the first plunger arm and the third transition edge of the first plunger arm and a surface between the second transition edge of the second plunger arm and the third transition edge of the second plunger arm, the second contact surface configured to contact the firing engagement mechanism subsequent to contact by the first contact surface. 2. The automatic injection device of claim 1, wherein the firing engagement mechanism is configured to engage the first and second contact surfaces of the first plunger arm and the second plunger arm, the firing engagement mechanism actuating the syringe plunger when the firing engagement mechanism is activated by a minimum force of between 5 N and 25 N. 3. The automatic injection device of claim 2, wherein, upon actuation of the syringe plunger, the pressurizer of the syringe plunger pressurizes a dose of TNF inhibitor in a syringe barrel and causes the dose of TNF inhibitor to be expelled from the syringe barrel. 4. The automatic injection device of claim 1, wherein the polymeric material of the syringe plunger has a flexural modulus of between 2,000 MPa and 5,500 MPa. 5. The automatic injection device of claim 1, wherein the first and second contact surfaces have a surface texture that is substantially rough. 6. The automatic injection device of claim 1, wherein the first and second contact surfaces have a surface texture that is substantially smooth. 7. The automatic injection device of claim 1, wherein the second contact surface is disposed at a second angle of 6°-38° relative to the longitudinal axis of the syringe plunger. 8. The automatic injection device of claim 1, wherein the second contact surface is disposed at a second angle of 8°-25° relative to the longitudinal axis of the syringe plunger. 9. The automatic injection device of claim 1, wherein the first and second plunger arms are separated by a third angle of between 0.5° and 2.0°. 10. The automatic injection device of claim 1, wherein the first and second plunger arms are separated by a distance of between 2.55 mm and 4.25mm. 11. The automatic injection device of claim 1, wherein the first and second plunger arms are separated by a distance of 3.05 mm. 12. The automatic injection device of claim 1, wherein the polymeric material is selected from the group consisting of thermoplastic materials and thermosetting materials. 13. The automatic injection device of claim 12, wherein the thermoplastic materials are selected from the group consisting of polyacetal, polycarbonate, polyacrylate, polyamide, polyester, acryonitrile-butadiene-styrene (ABS), polyvinyl chloride (PVC) and their copolymers, terpolymers, and filled composites thereof. 14. The automatic injection device of claim 13, wherein the polyacetal materials are selected from the group consisting of acetal homopolymers, copolymers, and filled materials thereof. 15. The automatic injection device of claim 14, wherein the filled materials are glass sphere filled or glass fiber filled. 16. The automatic injection device of claim 12, wherein the thermosetting materials are selected from the group consisting of epoxy, acrylic, urethane, ester, vinyl ester, epoxy-polyester, acrylic-urethane, and flurovinyl. 17. The automatic injection device of claim 16, wherein the acrylic material comprises a reactive functionality selected from the group consisting of an acid, a hydroxyl group, and an epoxy group. 18. The automatic injection device of claim 16, wherein the epoxy material comprises a reactive functionality that can be cured by a method selected from the group consisting of visible, ultraviolet and thermal crosslinking. 19. The automatic injection device of claim 12, wherein the thermosetting materials are selected from the group consisting of an epoxy homopolymer, copolymer or filled composite thereof. 20. The automatic injection device of claim 1, wherein the first contact surface has an open segment between the first and second plunger arms. 21. The automatic injection device of claim 1, wherein the first and second plunger arms have a top point fixed configuration. 22. The automatic injection device of claim 1, wherein the first and second plunger arms have a mid-point fixed configuration. 23. The automatic injection device of claim 1, wherein the second bifurcated end further comprises: a third contact surface defined by a conical surface disposed on a side of the third transition edge of the first plunger arm opposite the second contact surface and a conical surface disposed on a side of the third transition edge of the second plunger arm opposite the second contact surface, the third contact surface configured to contact a portion of the firing body. 24. The automatic injection device of claim 23, wherein the third contact surface is disposed at an angle of 62 degrees to 82 degrees relative to the longitudinal axis of the syringe plunger.
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