초록 ▼

A fluid sample vessel includes inlet and vent tube fittings formed at one end of a container with an opposite open end closed by a needle septum. A support cap is removably engaged to the container to support the container and protect terminal ends of inlet and vent tubular branches coupled to the f

A fluid sample vessel includes inlet and vent tube fittings formed at one end of a container with an opposite open end closed by a needle septum. A support cap is removably engaged to the container to support the container and protect terminal ends of inlet and vent tubular branches coupled to the fittings. The support cap includes a pair of opposite legs with outwardly directed tabs for mounting within a centrifuge while supporting the cryopreservation container.

대표청구항 ▼

1. A cryopreservation device comprising: a container for receiving and storing a liquid sample under cryopreservation conditions, said container having a hollow interior, and an outlet opening;a first tube fluidly communicating with said hollow interior, said first tube defining a vent passageway;a

1. A cryopreservation device comprising: a container for receiving and storing a liquid sample under cryopreservation conditions, said container having a hollow interior, and an outlet opening;a first tube fluidly communicating with said hollow interior, said first tube defining a vent passageway;a filter element disposed within said vent passageway;a second tube fluidly communicating with said hollow interior, said second tube defining an inlet passageway between a first end opening into said hollow interior and a sealed second end, and wherein said second tube is configured for connection to a source of liquid to be cryogenically preserved; anda needle septum sealing said outlet opening, said needle septum configured for removal of a stored liquid through a needle, and wherein said container is hermetically sealed. 2. The cryopreservation device of claim 1, wherein said second tube comprises heat-sealable sterile tubing. 3. The cryopreservation device of claim 2, wherein said second tube further comprises an input needle septum at said sealed second end. 4. The cryopreservation device of claim 2, wherein said second tube further comprises a needle-less port at said sealed second end. 5. The cryopreservation device of claim 2, wherein said second tube further comprises a heat sealed portion at said sealed second end. 6. The cryopreservation device of claim 1, wherein said filter element is gas permeable but generally liquid impermeable. 7. The cryopreservation device of claim 1, wherein said filter element is a sterile micro-filter. 8. The cryopreservation device of claim 1, further comprising a removable septum cover. 9. The cryopreservation device of claim 8, wherein said removable septum cover comprises a foil film. 10. The cryopreservation device of claim 1, wherein said container has a storage volume of 2-5 mL. 11. The cryopreservation device of claim 1, further comprising a cryoprotectant received within said container. 12. The cryopreservation device of claim 1, wherein said device is comprised of materials suitable to remain hermetically sealed at cryopreservation conditions at a temperature as low as −196° C. 13. A method of cryogenically storing a sample, said method comprising: introducing a liquid sample into a cryopreservation device as described in claim 1; andstoring said device at cryopreservation conditions at a temperature as low as −196° C. 14. A sample container device comprising: a container for receiving a sample, said container comprising an elongated body, said body defining a hollow interior from an open end and being closed at the opposite end by an inlet tube fitting and a vent tube fitting opening to said hollow interior;a gas permeable sterile micro-filter received in said vent tube fitting;a needle septum closing said open end; anda length of heat sealable tubing coupled to said inlet fitting, wherein the flexible tubing is comprised of material suitable to form a heat seal that withstands cryopreservation conditions at temperature as low as −196° C. without compromising the heat seal, and wherein said heat sealable tubing is sealed. 15. The device of claim 14, further comprising a needle septum sealing said heat sealable tubing. 16. The device of claim 14, further comprising a removable septum cover. 17. The device of claim 16, wherein said removable septum cover comprises a foil film. 18. The device of claim 14, further comprising a cryoprotectant received within said container. 19. The device of claim 14, wherein said device is hermetically sealed. 20. The device of claim 14, wherein said device is comprised of materials suitable to remain hermetically sealed at cryopreservation conditions at a temperature as low as −196° C. 21. The cryopreservation device of claim 14, further comprising a needle-less port sealing said heat sealable tubing. 22. The cryopreservation device of claim 14, further comprising a heat sealed portion sealing said heat sealable tubing.