Distributed neuro-modulation system with auxiliary stimulation-recording control units
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61N-001/36
A61N-001/05
H01B-007/00
A61N-001/375
A61N-001/368
출원번호
US-0867425
(2015-09-28)
등록번호
US-9597508
(2017-03-21)
발명자
/ 주소
McLaughlin, Bryan
Lachapelle, John
Sriram, Tirunelveli S.
Smith, Brian
출원인 / 주소
THE CHARLES STARK DRAPER LABORATORY, INC.
대리인 / 주소
Lando & Anastasi, LLP
인용정보
피인용 횟수 :
0인용 특허 :
9
초록▼
Systems and methods for modulating a physiological process are provided to enable precise delivery of signals to a predetermined treatment site. The systems may comprise an implantable device and an electrical lead body. The electrical lead body may comprise a plurality of transducer contacts in clo
Systems and methods for modulating a physiological process are provided to enable precise delivery of signals to a predetermined treatment site. The systems may comprise an implantable device and an electrical lead body. The electrical lead body may comprise a plurality of transducer contacts in close proximity to an end of the electrical lead body, and a control unit positioned within the lead body in close proximity to the plurality of transducer contacts.
대표청구항▼
1. A physiological electrical lead body comprising: an array of transducer contacts in close proximity to an end of the electrical lead body; anda control unit positioned within the lead body in close proximity to and in communication with the array of transducer contacts, the control unit construct
1. A physiological electrical lead body comprising: an array of transducer contacts in close proximity to an end of the electrical lead body; anda control unit positioned within the lead body in close proximity to and in communication with the array of transducer contacts, the control unit constructed and arranged to enable precise delivery of signals to a predetermined treatment site and comprising: at least one electrical input contact; anda plurality of electrical output contacts, wherein a quantity of the electrical output contacts is greater than a quantity of the electrical input contacts. 2. The electrical lead body of claim 1, wherein a diameter of the lead body is less than about 2 mm. 3. The electrical lead body of claim 2, wherein the diameter is about 1.3 mm. 4. The electrical lead body of claim 1, wherein the array of the transducer contacts comprises at least about 8 transducer contacts. 5. The electrical lead body of claim 1, wherein a distance between the control unit and the end of the lead body is less than about 5 cm. 6. The electrical lead body of claim 1, wherein the control unit is encapsulated with a material. 7. The electrical lead body of claim 5, wherein the encapsulation with the material provides for a hermetic seal. 8. The electrical lead body of claim 1, further comprising a plurality of filaments connecting the plurality of the electrical output contacts to the array of transducer contacts, the filaments having a diameter of less than about 0.150 mm. 9. The electrical lead body of claim 1, wherein at least a portion of the lead body is constructed and arranged to be implantable in a subject. 10. The electrical lead body of claim 1, wherein the array of transducer contacts are selected from the group consisting of electrodes contacts, optical contacts, acoustic contacts, induction coil contacts, magnetic coil contacts, and combinations thereof. 11. A system for modulating a physiological process, comprising: an implantable device comprising an energy source, the implantable device constructed and arranged to provide a signal; andan electrical lead body connected to the implantable device and comprising: an array of transducer contacts in close proximity to an end of the electrical lead body;a control unit positioned within the lead body in close proximity to the array of transducer contacts and constructed and arranged to enable precise delivery of signals to a predetermined treatment site, the control unit comprising: at least one electrical input contact; anda plurality of electrical output contacts, wherein a quantity of the electrical output contacts is greater than a quantity of the electrical input contacts. 12. The system of claim 11, wherein the array of transducer contacts are disposed to perform at least one of sensing at least one parameter of the physiological process, transmitting at least one parameter of the physiological process, stimulating the physiological process, and inhibiting the physiological process. 13. The system of claim 12, wherein the control unit is constructed and arranged to record at least one parameter of the physiological process. 14. The system of claim 11, wherein a diameter of the electrical lead is less than about 2 mm. 15. The system of claim 11, wherein the array of transducer contacts comprises at least about 8 transducer contacts. 16. The system of claim 11, wherein a distance between the control unit and the end of the lead is less than about 5 cm. 17. The system of claim 11, wherein the control unit is encapsulated with a material. 18. The system of claim 17, wherein the encapsulation with the material provides a hermetic seal. 19. The system of claim 11, wherein the plurality of the electrical output contacts are connected to the array of transducer contacts by a plurality of filaments, each filament having a diameter of less than about 0.150 mm. 20. The system of claim 11, wherein the electrical lead is implantable in a subject. 21. The system of claim 11, wherein the implantable device provides power to the control unit to energize the control unit. 22. The system of claim 11, wherein: the control unit is configured to receive at least one first input signal from the implantable device and to transmit a plurality of output signals to the array of transducer contacts; andthe plurality of output signals is based at least in part on the at least one first input signal from the implantable device and on a control function of the control unit. 23. The system of claim 22, wherein: the control unit is further configured to receive at least one second input signal from the array of transducer contacts; andthe plurality of output signals is modulated in response to the at least one electrical signal from the array of transducer contacts. 24. The system of claim 11, wherein the array of transducer contacts are selected from the group consisting of electrode contacts, optical contacts, acoustic contacts, induction coil contacts, magnetic coil contacts, and combinations thereof. 25. A method of treating a condition in a subject, comprising: generating a first input signal from an implantable device;transmitting the first input signal from the implantable device to a control unit positioned in an electrical lead body comprising a first end and an array of transducer contacts in close proximity to the first end;generating a plurality of output signals based on the first input signal from the implantable device and on a control function of the control unit; andtransmitting the plurality of output signals from the control unit to the array of transducer contacts to provide a precise delivery of signals to a predetermined treatment site. 26. The method of claim 25, further comprising transmitting at least one second input signal from the array of transducer contacts to the control unit. 27. The method of claim 25, further comprising modulating at least one parameter of the plurality of output signals in response to the at least one second input signal from the array of transducer contacts. 28. The method of claim 25, further comprising recording the at least one second input signal from the array of transducer contacts. 29. The method of claim 25, wherein each transducer contact of the array of transducer contacts performs the act of at least one of sensing, transmitting, stimulating, and inhibiting. 30. The method of claim 25, wherein the array of transducer contacts are selected from the group consisting of electrodes contacts, optical contacts, acoustic contacts, induction coil contacts, magnetic coil contacts, and combinations thereof. 31. The method of claim 25, further comprising energizing the control unit from the implantable device.
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