Auto-titration bi-level pressure support system and method of using same
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61M-016/00
A61M-016/20
출원번호
US-0924275
(2007-10-25)
등록번호
US-9629970
(2017-04-25)
발명자
/ 주소
Matthews, Greg
Duff, Winslow K
Martin, Daniel
Shankar, Uday S
Ressler, Heather
출원인 / 주소
KONINKLIJKE PHILIPS N.V.
대리인 / 주소
Haas, Michael W.
인용정보
피인용 횟수 :
1인용 특허 :
38
초록▼
A bi-level pressure support system and method of treating disordered breathing that optimizes the pressure delivered to the patient during inspiration and expiration to treat the disordered breathing while minimizing the delivered pressure for patient comfort. The pressure generating system generate
A bi-level pressure support system and method of treating disordered breathing that optimizes the pressure delivered to the patient during inspiration and expiration to treat the disordered breathing while minimizing the delivered pressure for patient comfort. The pressure generating system generates a flow of breathing gas at an inspiratory positive airway pressure (IPAP) during inspiration and at an expiratory positive airway pressure (EPAP) during expirations. A controller monitor at least one of the following conditions: (1) snoring, (2) apneas, (3) hypopneas, or (4) a big leak in the pressure support system and adjusts the IPAP and the EPAP based on the occurrence of any one of these conditions.
대표청구항▼
1. A bi-level auto-titration pressure support system comprising: (a) a pressure generating system adapted to generate a flow of breathing gas at an inspiratory positive airway pressure (IPAP) during inspiration and at an expiratory positive airway pressure (EPAP) during expiration;(b) a patient circ
1. A bi-level auto-titration pressure support system comprising: (a) a pressure generating system adapted to generate a flow of breathing gas at an inspiratory positive airway pressure (IPAP) during inspiration and at an expiratory positive airway pressure (EPAP) during expiration;(b) a patient circuit having a first end adapted to be coupled to the pressure generating system and a second end adapted to be coupled to an airway of a patient;(c) a monitoring system associated with the patient circuit or the pressure generating system and adapted to measure a parameter indicative of a pressure at a patient's airway, a flow of gas in such a patient's airway, or both and to output a pressure signal, a flow signal indicative thereof, respectively, or both; and(d) a controller coupled to the monitoring system and the pressure generating system, for controlling the pressure generating system based on the output of the monitoring system, wherein the controller is programmed to monitor each of the following conditions: (1) snoring, (2) apneas, (3) hypopneas, and (4) a big leak in the pressure support system, wherein the big leak is a system leak that is substantially greater than any intentional system leaks, and wherein the controller is programmed to: (a) increase the EPAP without changing the IPAP, responsive to a determination that the patient is experiencing only apneas and not hypopneas, or is experiencing a combination of apneas and hypopneas, (b) decrease the IPAP without changing the EPAP, responsive to a detection of the big leak, (c) increase the IPAP without changing the EPAP, responsive to a determination that the patient is experiencing only hypopneas and not apneas, and (d) either increase the EPAP without changing the IPAP increase the IPAP without changing the EPAP responsive to a determination that the patient is snoring. 2. The system of claim 1, wherein the controller performs an auto-titration process in which the controller adjusts the IPAP and the EPAP to determine an optimal IPAP for the patient. 3. The system of claim 1, wherein the controller: (a) causes the pressure generating system to reduce or modify the EPAP during at least a portion of the expiratory phase by some amount to provide a degree of pressure relief during the at least a portion of the expiratory phase;(b) causes the pressure generating system to reduce or modify the IPAP during at least a portion of the inspiratory phase by some amount to provide a degree of pressure relief during the at least a portion of the inspiratory phase; or(c) causes the pressure generating system to reduce or modify the EPAP during at least a portion of the expiratory phase by some amount to provide a degree of pressure relief during the at least a portion of the expiratory phase, and causes the pressure generating system to reduce or modify the IPAP during at least a portion of the inspiratory phase by some amount to provide a degree of pressure relief during the at least a portion of the inspiratory phase. 4. The system of claim 1, further comprising an input device for selecting activation of a ramp cycle, wherein the controller (a) decreases the IPAP and the EPAP responsive to activation of the pressure ramp, and (b) thereafter increases the IPAP and EPAP, and wherein the controller adjusts the IPAP and the EPAP during a pressure increase portion of the ramp cycle. 5. A method of providing a bi-level auto-titration pressure support therapy to a patient, comprising: (a) generating a flow of gas at an inspiratory positive airway pressure (IPAP) during inspiration and at an expiratory positive airway pressure (EPAP) during expirations;(b) coupling a first of a patient circuit to the pressure generating system and coupling a second end of the patient circuit an airway of a patient;(c) monitor each of the following conditions: (1) snoring, (2) apneas, (3) hypopneas, and (4) a big leak in the pressure support system, based on a pressure of a rate of the flow of gas, wherein the big leak is a leak that is substantially greater than any intentional system leaks; and(d) (i) increasing the EPAP without changing the IPAP responsive to determining that the patient is experiencing only apneas and not hypopneas, or is experiencing a combination of apneas and hypopneas, (ii) decreasing the IPAP without changing the EPAP responsive to detecting the big leak, (iii) increasing the IPAP without changing the EPAP responsive to determining that the patient is experiencing only hypopneas and not apneas, and (iv) either increasing the EPAP without changing the IPAP or increasing the IPAP without changing the EPAP responsive to determining that the patient is snoring. 6. The method of claim 5, further comprising performing an auto-titration process in which the IPAP and the EPAP are adjusted to determine an optimal IPAP for the patient. 7. The method of claim 5, further comprising: (a) reducing or modifying the EPAP during at least a portion of the expiratory phase by some amount to provide a degree of pressure relief during the at least a portion of the expiratory phase;(b) reducing or modifying the IPAP during at least a portion of the inspiratory phase by some amount to provide a degree of pressure relief during the at least a portion of the inspiratory phase; or(c) reducing or modifying the EPAP during at least a portion of the expiratory phase by some amount to provide a degree of pressure relief during the at least a portion of the expiratory phase, and reducing or modifying the IPAP during at least a portion of the inspiratory phase by some amount to provide a degree of pressure relief during the at least a portion of the inspiratory phase. 8. The method of claim 5, further comprising choosing between adjusting either the EPAP, the IPAP, or a combination of EPAP and IPAP based on a monitored condition of the patient, a monitored condition of a pressure support system that provides a flow of gas to such a patient, an input provided to the pressure support system, or any combination thereof. 9. The method of claim 5, executing a ramp cycle that includes: (a) decreasing the IPAP and the EPAP responsive to activation of the ramp cycle, and(b) thereafter increasing the IPAP and EPAP, wherein the IPAP and the EPAP are permitted to be adjusted during a pressure increase portion of the ramp cycle. 10. A bi-level auto-titration pressure support system comprising: a pressure generating system adapted to generate a flow of breathing gas at an inspiratory positive airway pressure (IPAP) during inspiration and at an expiratory positive airway pressure (EPAP) during expiration;a patient circuit having a first end adapted to be coupled to the pressure generating system and a second end adapted to be coupled to an airway of a patient;a monitoring system associated with the patient circuit or the pressure generating system and adapted to measure a parameter indicative of a pressure at a patient's airway, a flow of gas in such a patient's airway, or both and to output a pressure signal indicative thereof, a flow signal indicative thereof, respectively, or both; anda controller coupled to the monitoring system and the pressure generating system, and adapted to control the IPAP and the EPAP based on the output of the monitoring system, wherein the controller is programmed to operate according to one control layer in a set of prioritized control layers, wherein each control layer in the set of prioritized control layers competes for control of the pressure generating system with the other control layers, and wherein each control layer implements a unique pressure control process for controlling the IPAP, the EPAP, or both. 11. The system of claim 10, wherein each control layer in the set of prioritized control layer includes: a detection module that receives the pressure signal, the flow signal, or both;a monitoring module that monitors an output of the detection module to determine whether to request that the control layer take control of the pressure generating system; anda control module that controls the operation of the pressure generating system responsive to the control layer being granted control thereof. 12. The system of claim 10, wherein the set of prioritized control layers include: (a) flow limit control layer that monitors the flow signal to determine whether the pressure generating system is exhibiting a large leak indicative of the patient circuit not being connected to an airway of a patient, and causes the pressure generating system to lower the IPAP, the EPAP, or both responsive to detection of the large leak and maintains the pressure generating system at the lower pressure;(b) snore control layer that monitors the flow signal, the pressure signal, or both for snoring, and causes the pressure generating system to increase the IPAP, the EPAP, or both responsive to detection of snore;(c) a big leak control layer that monitors the flow signal to determine whether the pressure generating system is exhibiting a leak that is less than the large leak but great enough to cause the pressure support system to not operate reliably, and causes the pressure generating system to lower the IPAP, the EPAP, or both responsive to detection of the large leak for predetermined period of time;(d) an apnea/hypopnea control layer that monitors the flow signal, the pressure signal, or both to determine whether the patient is experiencing an apnea, a hypopnea, or both, and causes the pressure generating system to adjust the IPAP, the EPAP, or both responsive to detection of apnea, hypopnea, or both;(e) a variable breathing control layer that monitors the flow signal to determine whether the patient is experiencing erratic breathing, and causes the pressure generating system to adjust the IPAP, the EPAP, or both responsive to detection of erratic breathing; and(f) an auto-titration control layer that controls the IPAP, the EPAP, or both responsive to proactively search for a pressure that optimizes the pressure provided to the patient to treat disordered breathing. 13. The system of claim 10, further comprising a manual input for controlling the operation of the pressure support system, and wherein the set of prioritized control layers include at least one first control layer that is initiated based on the manual input and at least one second control layer that is initiated based on the pressure signal, the flow signal or both, wherein the at least one first control layer has a higher priority than the at least one second control layer. 14. The system of claim 13, wherein the first control layer is a ramp control layer that causes the pressure generating system to gradually increase the IPAP, the EPAP, or both from a relatively low level to a target level responsive to receipt of a ramp activation signal as the manual input.
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이 특허에 인용된 특허 (38)
Remmers John Edward (Calgary CAX) Feroah Thomas Richard (Calgary CAX), Auto CPAP system and method for preventing patient disturbance using airflow profile information.
Matthews, Greg; Duff, Winslow K; Martin, Daniel; Shankar, Uday S; Ressler, Heather, Auto-titration bi-level pressure support system and method of using same.
Sullivan Colin E. (Sidney AUX) Lynch Christopher (Sidney AUX), Device and method for monitoring breathing during sleep, control of CPAP treatment, and preventing of apnea.
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Sanders Mark H. (Pittsburgh PA) Zdrojkowski Ronald J. (Pittsburgh PA), Method and apparatus for maintaining airway patency to treat sleep apnea and other disorders.
Rapoport David M. (New York NY) Norman Robert G. (New Windsor NY), Method and apparatus for optimizing the continuous positive airway pressure for treating obstructive sleep apnea.
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