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Methods for DNA sequencing and analysis using multiple tiers of aliquots

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C12Q-001/68
  • C07H-021/04
  • C07K-001/04
출원번호 US-0971801 (2013-08-20)
등록번호 US-9637784 (2017-05-02)
발명자 / 주소
  • Drmanac, Radoje
출원인 / 주소
  • Complete Genomics, Inc.
대리인 / 주소
    Kilpatrick Townsend & Stockton LLP
인용정보 피인용 횟수 : 0  인용 특허 : 113

초록

The invention provides methods and kits for ordering sequence information derived from one or more target polynucleotides. In one aspect, one or more tiers or levels of fragmentation and aliquoting are generated, after which sequence information is obtained from fragments in a final level or tier. E

대표청구항

1. A method of processing genomic DNA, comprising: preparing a first tier of aliquots, at least some of which contain one or more polynucleotides that include a nucleotide sequence from a portion of a genome tagged with an oligonucleotide such that polynucleotides present in different aliquots have

이 특허에 인용된 특허 (113)

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