A reshapable retention device for insertion at a dental site and contact with adjacent dental surfaces, for the controlled delivery to the dental site of at least one material having a predetermined intraoral activity. The retention device comprises at least one matrix containing the material. The r
A reshapable retention device for insertion at a dental site and contact with adjacent dental surfaces, for the controlled delivery to the dental site of at least one material having a predetermined intraoral activity. The retention device comprises at least one matrix containing the material. The retention device is adapted for physically affixing at the dental site for at least a predetermined time period correlated to the delivery of a predetermined portion of the at least one matrix to the dental site in a controlled single, bi or multiphase pattern. The retention device comprises a first configuration in which the overall dimensions of the retention device are larger than at least one dimension of the dental site. The first configuration is reshapable to a second configuration in which at least one dimension of the retention device is reduced to enable physically affixing the retention device at the dental site. In the second configuration the retention device comprises a predetermined shape having contours for affixing at the dental surfaces.
대표청구항▼
1. A substrate having a substrate width dimension, a substrate length dimension and a substrate thickness dimension, the substrate made from a polymeric matrix material and capable of containing at least one active material having a predetermined intraoral activity or at least one inactive material,
1. A substrate having a substrate width dimension, a substrate length dimension and a substrate thickness dimension, the substrate made from a polymeric matrix material and capable of containing at least one active material having a predetermined intraoral activity or at least one inactive material, wherein at least one of said substrate width dimension or said substrate length dimension is sufficiently large to enable at least two precursor portions of the substrate to be separated from the substrate, each precursor portion being manipulable to enable altering at least one of the shape and size of the precursor portion to thereby provide a retention device that is configured for being retained at a dental site and for delivering the active material or inactive material to a dental site, said substrate further comprising a plurality of separating facilitators defining separation boundaries between said precursor portions and configured for facilitating separation of respective said precursor portions from a remainder of said substrate; wherein said retention device is one of: substantially biodegradable, self-degradable, substantially resorbable and substantially non-resorbable, andfurther comprising stiffening elements embedded in the matrix material;wherein said stiffening elements comprise a plurality of fibers;wherein each said precursor portion is foldable about a fold line to thereby provide said retention device; andwherein said fibers are arranged such as not to cross said fold line. 2. The substrate according to claim 1, wherein said separating facilitator includes one of the group consisting of the following: at least one first weakened line configured for facilitating separation of each said precursor portion from an adjoining precursor portionat least one first weakened line configured for facilitating separation of each said precursor portion from an adjoining precursor portion via a respective connector portion therebetweenan indented line;a perforated line;a physical indicating mark along a separation line; anda chemically treated indicating mark along a separation line. 3. The substrate according to claim 1, wherein each said precursor portion is trimmable to thereby provide the retention device. 4. The substrate according to claim 1, wherein said retention device is soft for easy interproximal insertion, and provides a cleaning effect which would serve as an alternative or supplement to flossing and releases at least one antimicrobial or cleansing agent and/or at least one remineralizing or mineralizing agent, and/or at least one demineralization inhibiting agent. 5. The substrate according to claim 1, wherein the polymeric matrix material comprises a hydrophilic polymer such as to enable the respective said retention device to be affixed by swelling in situ by the hydration of the respective matrix in the oral cavity after accommodation of said retention device at the dental site. 6. The substrate according to claim 1, wherein said fibers are arranged in generally parallel relationship with the fold line of the respective said precursor portion. 7. The substrate according to claim 1, wherein said fibers are at an angle of up to ±45° to the fold line. 8. The substrate according to claim 1, wherein said fibers are arranged randomly aligned in the matrix. 9. The substrate according to claim 1, wherein said fibers are arranged aligned in two or more parallel groups to form various ordered mesh-like alignments. 10. The substrate according to claim 9, wherein said mesh-like alignments can be uniform or restricted to specific areas with respect to the matrix or its precursor portion. 11. The substrate according to claim 9, wherein said fibers include one or more of or made from any one of or combination of: glass fibers, carbon fibers, natural silk fibers, silicon carbide and nitride, boron, alumina (Al2O3), synthetic polymers, and tin chains. 12. The substrate according to claim 1, wherein said fibers are one of bound to the matrix or unbound within the matrix. 13. A substrate having a substrate width dimension, a substrate length dimension and a substrate thickness dimension, the substrate made from a polymeric matrix material and containing at least one active material having a predetermined intraoral activity or at least one inactive material, wherein at least one of said substrate width dimension or said substrate length dimension is sufficiently large to enable at least two precursor portions of the substrate to be separated from the substrate, each precursor portion being manipulable to enable altering at least one of the shape and size of the precursor portion to thereby provide a retention device that is configured for being retained at a dental site and for delivering the active material or inactive material to a dental site, said substrate further comprising a plurality of separating facilitators defining separation boundaries between said precursor portions and configured for facilitating separation of respective said precursor portions from a remainder of said substrate; wherein said retention device is one of: substantially biodegradable, self-degradable, substantially resorbable and substantially non-resorbable, andfurther comprising stiffening elements embedded in the matrix material;wherein said stiffening elements comprise a plurality of fibers;wherein each said precursor portion is foldable about a fold line to thereby provide said retention device; andwherein said fibers are arranged such as not to cross said fold line. 14. The substrate according to claim 13, wherein the polymeric matrix material comprises a hydrophilic polymer that enables the respective said retention device to be affixed by swelling in situ by the hydration of the respective matrix in the oral cavity after accommodation of said retention device at the dental site. 15. The substrate according to claim 13, wherein the matrix material further comprises any one of an enhancing agent for enhancing the application and release of the active material such as plasticizer, elasticizer, coloring agents, adhering agent, filler, softener, binder and preserving or sterilizing agent or any one of an auxiliary agent such as an antimicrobial agent, anti plaque agent, anti inflammatory agent, antioxidant, humectants, nutrient analgesic or anaesthetic agent, anti calculus agent, cleaning agent, effervescent agent, tooth desensitizing agent, staining agent, hemostatic agent, astringent agent, whitening or bleaching agent, flavoring or sweetening agent, breath freshener, or sensate. 16. The substrate according to claim 13, wherein the active material is at least one of a fluoridation agent, a antimicrobial agent, a remineralization agent, a mineralization agent, a demineralization inhibiting agent, a cleaning agent, a tooth desensitizing agent and a tooth whitening/bleaching agent.
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이 특허에 인용된 특허 (39)
Wolk Roger S. (28 Malibu Colony Dr. Malibu CA 90265) Tapocik Claudette (4105 Indus Way Riverside CA 92503), Automatic dental flossing device.
Dunn Richard L. (451 Boardwalk Dr. RLD ; Apt. 501 Fort Collins CO 80526) English James P. (2500 Melinda Cir. Birmingham AL 35214) Cowsar Donald R. (4657 Round Forest Dr. Birmingham AL 35213) Vanderbi, Biodegradable in-situ forming implants and methods of producing the same.
Dunn Richard L. (Fort Collins CO) English James P. (Birmingham AL) Cowsar Donald R. (Birmingham AL) Vanderbilt David P. (Birmingham AL), Biodegradable in-situ forming implants and methods of producing the same.
Dunn Richard L. (Fort Collins CO) Tipton Arthur J. (Fort Collins CO) Southard George L. (Fort Collins CO) Rogers Jack A. (Fort Collins CO), Biodegradable polymer composition.
Dunn Richard L. (Fort Collins CO) Tipton Arthur J. (Fort Collins CO) Southard George L. (Fort Collins CO) Rogers Jack A. (Fort Collins CO), Biodegradable system for regenerating the periodontium.
Sagel Paul Albert ; Dirksing Robert Stanley ; Rohman Frederick James, Delivery system for an oral care substance using a strip of material having low flexural stiffness.
Newman Michael G. (809 Alma Real Dr. Pacific Palisades CA 90272) Carranza ; Jr. Fermin A. (10577 Eastborne Ave. Los Angeles CA 90024), Fluoride-coated dental floss.
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