초록 ▼

Dental composition comprising (i) a particulate filler; (ii) a polymerizable hydrolysis-stable compound of the following formula (1) AXn wherein A is a linker group containing at least n nitrogen atoms and optionally one or more acidic groups, X are moieties containing a polymerizable double bond an

Dental composition comprising (i) a particulate filler; (ii) a polymerizable hydrolysis-stable compound of the following formula (1) AXn wherein A is a linker group containing at least n nitrogen atoms and optionally one or more acidic groups, X are moieties containing a polymerizable double bond and forming an amide bond with a nitrogen atom of A, which X may be the same or different and are represented by the following formula (2) wherein R1 and R2 are independent from each other and represent a hydrogen atom, a C1-6 alkyl group or a group —(CH2)m—Z, wherein Z is COOM, OPO3M2, PO3M2, SO3M, and M is independently a hydrogen atom or a metal atom, and m is an integer of from 0 to 6, L is a bond, a C1-6 alkylene group; and n is an integer of at least 1; provided that at least one X cannot be a (meth)acryl group; and (iii) an initiator system.

대표청구항 ▼

1. A dental composition comprising: (i) a dental particulate filler;(ii) a polymerizable hydrolysis-stable compound of the following formula (1), AXn  (1)whereinA is a linker group containing at least n nitrogen atoms and optionally one or more acidic groups,X are moieties containing a polymerizable

1. A dental composition comprising: (i) a dental particulate filler;(ii) a polymerizable hydrolysis-stable compound of the following formula (1), AXn  (1)whereinA is a linker group containing at least n nitrogen atoms and optionally one or more acidic groups,X are moieties containing a polymerizable double bond and forming an amide bond with a nitrogen atom of A, which X may be the same or different and are represented by the following formula (2) whereinR1 and R2 are independent from each other and represent a hydrogen atom, a C1-6 alkyl group, or a —(CH2)m—Z group, wherein Z is COOM, OPO3M2, PO3M2, or SO3M, M is independently a hydrogen atom or a metal atom, and m is an integer of from 0 to 6,L is a bond or a C1-6 alkylene group; andn is an integer of at least 2;provided that L is a C1-6 alkylene group for at least one X; and(iii) a dental initiator system. 2. The dental composition according to claim 1, wherein the linker group is a linear or branched monomeric, oligomeric, polymeric or copolymeric group containing nitrogen atoms at the terminal positions. 3. The dental composition according to claim 1, wherein the polymerizable compound of formula (1) contains one or more acidic groups selected from carboxylic acid groups, phosphonic acid groups, sulfonic acid groups or phosphoric acid ester groups. 4. The dental composition according to claim 1, wherein the linker group, A, is a polyamide group obtained by a process comprising the step of a step-growth polymerization of a mixture containing a diamine of the following formula (3) and a compound of the following formula (4) having at least two carboxylic acid groups, said carboxylic acid groups may be present in the form of an anhydride, optionally in the presence of a compound of the following formula (5): R3(NHR′)y  (3)whereinR3 represents an y-valent C2-20 straight-chain, branched or cyclic hydrocarbon group which may optionally contain from 1 to 6 heteroatoms selected from nitrogen, oxygen, or sulphur atoms in the backbone of the hydrocarbon group, and optionally from 1 to 6 functional groups selected from hydroxyl groups, thiol groups and amino groups;R′ represents a hydrogen atom, an aliphatic hydrocarbon group, or a cycloaliphatic hydrocarbon group; andy represents an integer of at least 2; MOOC—R4—COOM  (4)wherein R4 represents a C1-20 straight-chain, branched, cyclic or aromatic hydrocarbon group which may optionally contain from 1 to 6 heteroatoms selected from nitrogen, oxygen, or sulphur atoms in the backbone of the hydrocarbon group, and optionally from 1 to 6 functional groups selected from carboxylic acid groups, hydroxyl groups, thiol groups and amino groups, and the M which may be the same or different, independently represent a hydrogen atom or a metal atom; wherein L, R1 and R2 are as defined in claim 1, and Y is a leaving group or Y forms an intramolecular anhydride group together with a carboxyl group present in R1 or R2 and the adjacent carbonyl group. 5. The dental composition according to claim 1, wherein the linker group is a polyoxyalkylene group containing nitrogen atoms at the terminal positions. 6. The dental composition according to claim 1, wherein the polymerizable hydrolysis-stable compound of formula (1) is water-soluble and has a molecular weight of from 300 to 10,000 Da. 7. The dental composition according to claim 1, which contains a fluoride containing compound. 8. The dental composition according to claim 1 wherein the dental particulate filler is an inorganic particulate filler selected from the group of glass, metal oxides, metal hydroxides, salts and mixtures thereof. 9. The dental composition according to claim 1, which provides a shear strength (ISO/TS 11405 (2003)) after curing to dentin or enamel of at least 3 MPa. 10. The dental composition according to claim 1, which is a one-pack composition. 11. The dental composition according to claim 1, wherein R1 and R2 in formula (2) are independent from each other and represent a hydrogen atom, a C1-6 alkyl group or a group —(CH2)m—COOM, wherein M is hydrogen atom or a metal atom, and m is an integer of from 0 to 6. 12. A method comprising using a composition as defined in claim 1 to prepare a dental composition. 13. The method according to claim 12, wherein the dental composition is prepared as a dental restorative or dental prosthetic composition. 14. The dental composition according to claim 1, wherein the compound of formula (1) is further obtained by a process comprising a step of a step-growth polymerization of a mixture containing a diamine of the following formula (3) and a compound of the following formula (4) having at least two carboxylic acid groups, said carboxylic acid groups may be present in the form of an anhydride, in the presence of a compound of the following formula (5): R3(NHR′)y  (3)whereinR3 represents an y-valent C2-20 straight-chain, branched or cyclic hydrocarbon group which may optionally contain from 1 to 6 heteroatoms selected from nitrogen, oxygen, or sulphur atoms in the backbone of the hydrocarbon group, and optionally from 1 to 6 functional groups selected from hydroxyl groups, thiol groups and amino groups;R′ represents a hydrogen atom, an aliphatic hydrocarbon group, or a cycloaliphatic hydrocarbon group; andy represents an integer of at least 2; MOOC—R4—COOM  (4)wherein R4 represents a C1-20 straight-chain, branched, cyclic or aromatic hydrocarbon group which may optionally contain from 1 to 6 heteroatoms selected from nitrogen, oxygen, or sulphur atoms in the backbone of the hydrocarbon group, and optionally from 1 to 6 functional groups selected from carboxylic acid groups, hydroxyl groups, thiol groups and amino groups and the M which may be the same or different, independently represent a hydrogen atom or a metal atom; and wherein L, R1 and R2 are as defined in claim 1, and Y is a leaving group or Y forms an intramolecular anhydride group together with a carboxyl group present in R1 or R2 and the adjacent carbonyl group. 15. The dental composition according to claim 4, wherein the linker group is a linear or branched monomeric, oligomeric, polymeric or copolymeric group containing nitrogen atoms at the terminal positions. 16. The dental composition according to claim 4, wherein the polymerizable compound of formula (1) contains one or more acidic groups selected from carboxylic acid groups, phosphonic acid groups, sulfonic acid groups or phosphoric acid ester groups. 17. A dental composition comprising: (i) a dental particulate filler;(ii) a polymerizable hydrolysis-stable compound of the following formula (1) AXn  (1)whereinA is a linker group containing at least n nitrogen atoms and optionally one or more acidic groups;X are moieties containing a polymerizable double bond and forming an amide bond with a nitrogen atom of A, which X may be the same or different and are represented by the following formula (2) whereinR1 and R2 are independent from each other and represent a hydrogen atom, a C1-6 alkyl group, or a —(CH2)m—Z group, wherein Z is COOM, OPO3M2, PO3M2, or SO3M, M is independently a hydrogen atom or a metal atom, and m is an integer of from 0 to 6;L is a bond or a C1-6 alkylene group; andn is an integer of at least 2;provided that R1 represents a —(CH2)m—Z group for at least one X; and(iii) a dental initiator system. 18. A dental composition comprising: (i) a dental particulate filler;(ii) a polymerizable hydrolysis-stable compound of the following formula (1) AXn  (1)whereinA is a linker group containing at least one 1,4-cyclohexane bismethylamine group and optionally two or more acidic groups;X are moieties containing a polymerizable double bond and forming an amide bond with a nitrogen atom of A, which X may be the same or different and are represented by the following formula (2) whereinR1 and R2 are independent from each other and represent a hydrogen atom, a C1-6 alkyl group, or a —(CH2)m—Z group, wherein Z is COOM, OPO3M2, PO3M2, or SO3M, M is independently a hydrogen atom or a metal atom, and m is an integer of from 0 to 6;L is a bond or a C1-6 alkylene group; andn is an integer of at least 2;provided that at least one X cannot be a (meth)acryl group; and(iii) a dental initiator system.