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Treatment of erectile dysfunction and other indications

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/107
  • A61K-047/14
  • A61K-047/12
  • A61K-031/519
  • A61K-031/4985
  • A61K-031/53
  • A61K-009/00
  • A61K-009/06
  • A61K-031/198
  • A61K-031/495
  • A61K-031/506
  • A61K-047/36
  • A61K-047/10
  • A61K-047/16
  • A61K-047/26
  • A61K-047/02
  • A61K-047/18
  • A61K-047/22
  • A61K-047/06
출원번호 US-0290504 (2016-10-11)
등록번호 US-9675619 (2017-06-13)
발명자 / 주소
  • Fossel, Eric T.
출원인 / 주소
  • Strategic Science & Technologies, LLC
대리인 / 주소
    Wolf, Greenfield & Sacks, P.C.
인용정보 피인용 횟수 : 1  인용 특허 : 119

초록

The present invention generally relates to the transdermal delivery of various compounds. In some aspects, transdermal delivery may be facilitated by the use of a hostile biophysical environment. One set of embodiments provides a composition for topical delivery comprising a phosphodiesterase type 5

대표청구항

1. A method, comprising: applying a composition comprising a cream, gel, or lotion to the genital region of a male subject, wherein the composition produces an erection in less than 15 minutes after application, and wherein the composition comprises:a nitric oxide donor comprising L-arginine and/or

이 특허에 인용된 특허 (119)

  1. Radloff, Detlev; Wasner, Matthias, Active substance patch, kind to the skin, for transdermal administration of nonsteroidal antirheumatics.
  2. Mody Dhiraj S. (Hammonton NJ) Blank Robert G. (Hammonton NJ) Agisim Gary R. (Cherry Hill NJ) Chen Gloria Y. (Hammonton NJ), Analgesic compositions.
  3. Watanabe Kazuo (Shiga JPX) Tuchida Toshio (Shiga FL JPX) Schultz Duane R. (Miami FL), Anti-inflammatory and analgesic compounds, related compositions and methods for preparation and use thereof.
  4. Fossel, Eric T., Beneficial effects of increasing local blood flow.
  5. Saavedra Joseph E. (Thurmont MD) Keefer Larry K. (Bethesda MD) Roller Peter P. (Rockville MD) Akamatsu Miki (Rockville MD), Biopolymer-bound nitric oxide-releasing compositions, pharmaceutical compositions incorporating same and methods of trea.
  6. Aleem, Muhammad Azhar; Fath, Brian; Gaboury, Scott Howard, Bumper integrated forward radar mounting system.
  7. Samour Carlos M. ; Krauser Scott F., Cationic film-forming polymer compositions, and use thereof in topical agents delivery system and method of delivering.
  8. Samour Carlos M. ; Krauser Scott F., Cationic film-forming polymer compositions, and use thereof in topical agents delivery system and method of delivering.
  9. Daniel J. Smith ; Sibel Yazici TR, Chitosan-based nitric oxide donor compositions.
  10. Nakata Masanori (Odawara JPX) Inoue Shintaro (Odawara JPX) Sotomura Mikio (Odawara JPX) Taira Junsei (Hadano JPX) Miyamoto Itaru (Chigasaki JPX), Collagen metabolism ameliorant and its use.
  11. Adams, Michael A.; Heaton, Jeremy P. W.; Maurice, Donald H., Combination therapy for treatment of erectile dysfunction.
  12. Banerjee Pradip K. (King of Prussia PA), Compositions and method of controlling transdermal penetration of topical and systemic agents.
  13. Kenneth B Kirby ; Berno I. R. Pettersson, Jr., Compositions for rapid and non-irritating transdermal delivery of pharmaceutically active agents and methods for formulating such compositions and delivery thereof.
  14. Kirby, Kenneth B; Pettersson, Berno, Compositions for rapid and non-irritating transdermal delivery of pharmaceutically active agents and methods for formulating such compositions and delivery thereof.
  15. Kirby,Kenneth B; Pettersson,Berno, Compositions for rapid and non-irritating transdermal delivery of pharmaceutically active agents and methods for formulating such compositions and delivery thereof.
  16. Carniglia Francis J. (Windsor Locks CT) Kenyon Alan J. (Hartford CT), Compositions of matter and methods for increasing intracellular ATP levels and physical performance levels and for incre.
  17. Iovanni Carl F. (Quincy MA), Conditioning shampoo.
  18. Mausner Jack (New York NY), Cosmetic composition.
  19. Seguin, Marie-Christine, Cosmetic composition for slimming containing L-arginine, an L-arginine analogue, or one of their derivatives, for topical application.
  20. Weuffen Wolfgang (Ringstrasse 39 D-17498 Guest DEX) Kramer Axel (Georg-Engel-Strasse 20 D-17489 Greifswald DEX) Tirsch Christel (Rudolf-Weiss-Strasse 36 D-99947 Bad Langensalza DEX) Meffert Hans (Ora, Cosmetic or pharmaceutic preparations for improving hair quaility and stimulating growth of the hair.
  21. Pineau Nathalie,FRX ; Martin Richard,FRX ; Breton Lionel,FRX ; Aubert Lucien,FRX, Cosmetic/pharmaceutical compositions comprising microorganism culture media.
  22. Fossel, Eric T., Delivery of ibuprofen and other compounds.
  23. Fossel, Eric T., Delivery of ibuprofen and other compounds.
  24. Fossel, Eric T., Delivery of ibuprofen and other compounds.
  25. Fontanelli Luciano (Pisa ITX), Dermatological and cosmetic compositions.
  26. Tawashi Rashad (66 Hyde Park Beaconsfield ; Quebec CAX H9W 5L8 ), Drug delivery of nitric oxide.
  27. Drizen Alan,CAX ; Rothbart Peter,CAX ; Nath Gary M., Drug preparations for treating sexual dysfunction.
  28. Hsu, Tsung-Min; Jacobson, Eric C.; LoBello, Rose C.; Luo, Eric C., Dual enhancer composition for topical and transdermal drug delivery.
  29. Hsu, Tsung-Min; Jacobson, Eric C.; LoBello, Rose C.; Luo, Eric C., Dual enhancer composition for topical and transdermal drug delivery.
  30. Sibalis Dan (268 Hallock Rd. Stony Brook NY 11790) Rosen Sanford (64 E. 86th St. New York NY 10028), Electrolytic transdermal delivery of proteins.
  31. Maxwell Andrew J. ; Cooke John P., Enhancement of exercise performance by augmenting endogenous nitric oxide production or activity.
  32. Cooke John P. ; Dzau Victor J. ; Gibbons Gary H., Enhancement of vascular function by modulation of endogenous nitric oxide production or activity.
  33. Cooke, John P.; Dzau, Victor J.; Gibbons, Gary H., Enhancement of vascular function by modulation of endogenous nitric oxide production or activity.
  34. Gray Debora ; Schmelkin Nancy S. ; Alexander John ; Mark David A. ; Twyman Diana, Enternal formulation designed for optimized nutrient absorption and wound healing.
  35. Vromen,Jacob, Formulations for topical delivery of bioactive substances and methods for their use.
  36. Burcke ; Jr. Harry J. (1565 Kingswood Dr. Hillsborough CA 94010), Hand therapy apparatus and method therefor.
  37. Horn Dieter (Heidelberg DEX) Krueger Goetz (Aachen DEX) Spengler Reinhard (Ludwigshafen DEX), Hydrophilic theophylline powder formulation and its preparation.
  38. Luo, Eric C.; Jacobson, Eric C.; Hsu, Tsung-Min, Hydroxide-releasing agents as skin permeation enhancers.
  39. Sarpotdar Pramod P. (Audubon PA) Gaskill James L. (Devon PA) Giannini Robert P. (East Norriton PA) Daniels Charles R. (Erdenheim PA), L-a 상세보기
  • Samour Carlos ; Krauser Scott F., Lipophilic and amphiphilic or hydrophilic film-forming polymer compositions, and use thereof in topical agent delivery.
  • Katinger Hermann,ATX ; Vorauer-Uhl Karola,ATX ; Riedl Claus,ATX, Liposomal recombinant human superoxide-dismutase for the treatment of peyronie's disease.
  • Doherty ; Jr. Paul C. ; Place Virgil A. ; Smith William L., Local administration of phosphodiesterase inhibitors for the treatment of erectile dysfunction.
  • Lang Gnther (Reinheim DEX) Wendel Harald (Ober-Ramstadt DEX), Macromolecular, surface-active, quaternary, N-substituted chitosan derivatives as well as cosmetic composition based on.
  • Cameron William W. (Chicago IL), Medicated shampoo composition.
  • Byas-Smith Michael G., Method and compositions for controlling oral and pharyngeal pain using capsaicinoids.
  • Kaesemeyer W. H. (2433 McDowell St. August GA 30904), Method and formulation of stimulating nitric oxide synthesis.
  • Alptekin Aksan ; John J. McGrath, Method for controlling the chemical and heat induced responses of collagenous materials.
  • Hanada Seigo (Dazaifu JPX) Yamamoto Shinji (Dazaifu JPX), Method for promoting hair growth.
  • John Lezdey ; K. Anne Kronis ; Darren Lezdey, Method for treating infectious viral diseases.
  • Cauwenbergh Gerard F. M. J. (Vorselaar BEX), Method of topically treating acne vulgaris, hyperkeratotic dermatoses, and photo-aging of the skin.
  • Garvey, David S.; Letts, L. Gordon; Tam, Sang William, Methods using proton pump inhibitors and nitric oxide donors.
  • Troy H. Cooper, Misting apparatus for application of coating materials to skin surface.
  • Berner Bret ; Ebert Charles ; Mazzenga Gerard C. ; Otte John H., Mixed solvent mutually enhanced transdermal therapeutic system.
  • Garfield Robert E. (Friendswood TX) Balaban Alexandru T. (Galveston TX) Seitz William A. (Dickinson TX) Klein Douglas J. (Galveston TX) Lesko Melanie (Friendswood TX), N-nitroso-N-substituted hydroxylamines as nitric oxide donors.
  • Bing, Richard J., Nitric oxide donor compounds.
  • Haj-Yehia, Abdullah, Nitric oxide donors and pharmaceutical compositions containing them.
  • Hrabie, Joseph A.; Keefer, Larry K., Nitric oxide-releasing amidine- and enamine-derived diazeniumdiolates, compositions and uses thereof and method of making same.
  • Tseng Susan Y. (Staten Island NY) Helioff Michael W. (Westfield NJ) Chuang Jui-Chang (Wayne NJ) Krummel H. Karl (Montville NJ) Davis Mary R. (Suffern NY), Non-irritating skin and hair rejuvenating compostion having a pH between 1 and 6.5.
  • Samour Carlos M. ; Krauser Scott F. ; Gyurik Robert J., Non-steroidal antiinflammtory drug formulations for topical application to the skin.
  • Nakaguchi Osamu (Toyonaka JPX), Normal-pentadecyl nicotinate N-oxide and hair restorer comprising the same.
  • Marty Jean-Pierre (Montesson FRX), Novel cosmetic compositions.
  • Harrison Juan M. E. (Mountain View CA) Barclay Brian L. (Sunnyvale CA) Childers Jerry D. (Menlo Park CA) Wright Jeri D. (Dublin CA) Place Virgil A. (Kawaihae HI) Wong Patrick S. (Palo Alto CA), Oral osmotic device with hydrogel driving member.
  • Brand Larry M. (West Chester OH), Pharmaceutical products providing enhanced analgesia.
  • Erik Emil Anggard GB; Abdullah Ibrahim Haj-Yehia IL, Piperidine and pyrrolidine derivatives comprising a nitric oxide donor for treating stress.
  • Keefer Larry K. (Bethesda MD) Hrabie Joseph A. (Frederick MD), Polymer-bound nitric oxide/nucleophile adduct compositions, pharmaceutical compositions and methods of treating biologic.
  • Smith Daniel J. (Stow OH) Chakravarthy Debashish (Garrettsville OH) Keefer Larry K. (Bethesda MD), Polysaccharide-bound nitric oxide-nucleophile adducts.
  • Venkateshwaran Srinivasan ; Fikstad David ; Ebert Charles D., Pressure sensitive adhesive matrix patches for transdermal delivery of salts of pharmaceutical agents.
  • Chaudhuri Ratan K. (Lincoln Park NJ) Biss Russell B. (Wayne NJ) Merianos John J. (Middletown NJ), Process for producing an alpha or beta-hydroxy acid-vinylpyrrolidone polymer, copolymer or graft polymer complex in the.
  • Eisenberg Solomon R. (Newton MA) Samour Carlos M. (Newport RI), Process for transport of agents across the skin and compositions and articles useful therein.
  • Peter Ellis GB; Nicholas Kenneth Terrett GB, Pyrazolopyrimidinones for the treatment of impotence.
  • Kimura Haruo (Kyoto JPX) Sekino Yoshio (Osaka JPX) Masuya Takashi (Osaka JPX) Fukui Takao (Osaka JPX), Safety switch assembly.
  • Daley Edwin W. (Cincinnati OH) Yowler M. Pauline (Springfield Township ; Hamilton County OH), Shampoo compositions which impart high luster and manageability to hair.
  • Raaf Helmut (Bockenau DEX) Bimczok Rudolf (Mainz-Finthen DEX) Ittel Ingrid (Ingelheim DEX), Skin care composition.
  • Mausner Jack (New York NY), Skin cream composition.
  • Gibson Walter T. (Northamptonshire GB2), Skin treatment composition.
  • Kamishita Takuzo (Takatsuki JPX) Miyazaki Takashi (Nakaniikawa JPX) Okuno Yoshihide (Namerikawa JPX), Spray gel base and spray gel preparation using thereof.
  • Mentrup Edgar (Frankfurt DEX) Michel Christoph (Obertshausen DEX) Purmann Thomas (Aschaffenburg DEX), Stable small particle liposome preparations, their production and use in topical cosmetic, and pharmaceutical compositio.
  • Katz Martin (Menlo Park CA) Nacht Sergio (Los Altos CA) Heller Jorge (Woodside CA), System and method for transdermal drug delivery.
  • Seitz William A. ; Garfield Robert E. ; Balaban Alexandru T. ; Stewart Randall J., Systems and methods for topical treatment with nitric oxide.
  • Fossel, Eric T., Systems and methods for treatment of allergies and other indications.
  • Abad Rafael (Madrid ESX), Therapeutic and cosmetic compositions for treatment of skin.
  • Eric T. Fossel, Topical and oral delivery of arginine to cause beneficial effects.
  • Fossel Eric T., Topical and oral delivery of arginine to cause beneficial effects.
  • Luo, Eric C.; Hsu, Tsung-Min, Topical and transdermal administration of peptidyl drugs using hydroxide releasing agents as permeation enhancers.
  • Luo, Eric C.; Jacobson, Eric C.; Hsu, Tsung-Min, Topical and transdermal administration of peptidyl drugs with hydroxide-releasing agents as skin permeation enhancers.
  • Rovee David T. (Somerset NJ) Marvel John R. (East Brunswick NJ) Mezick James A. (East Brunswick NJ), Topical anti-inflammatory drug therapy.
  • Falk Rudolf Edgar,CAX ; Asculai Samuel Simon,CAX, Topical composition containing hyaluronic acid and NSAIDS.
  • Fossel, Eric T., Topical composition containing ibuprofen.
  • Fossel, Eric T., Topical composition containing naproxen.
  • Perricone Nicholas V. (27 Coginchaug Ct. Guilford CT 06437), Topical compositions and methods for treatment of skin damage and aging using catecholamines and related compounds.
  • Fossel, Eric T., Topical delivery of L-arginine to cause beneficial effects.
  • Fossel, Eric T., Topical delivery of L-arginine to cause beneficial effects.
  • Fossel Eric T., Topical delivery of L-arginine to cause tissue warming.
  • Fossel, Eric T., Topical delivery of arginine of cause beneficial effects.
  • Fossel Eric T., Topical delivery of arginine to overcome pain.
  • Hechtman Herbert B. (Chestnut Hill MA), Topical formulations and methods for treating hemorrhoidal pain and sphincter and smooth muscle spasm in the gastrointes.
  • Russell Meri Charmyne, Topical nitric oxide donor compositions.
  • Muller, Walter, Topical plaster with non-steroidal antirheumatic agents with an acid group.
  • Altadonna James, Topical preparation and method for pain relief.
  • Verbiscar, Anthony J., Topical transdermal treatments.
  • Prejean,Helen; Malcolm,Mark, Topical treatment for psoriasis.
  • Durif Franck,FRX ; El-Rashidy Ragab, Transdermal administration of apomorphine.
  • Hsu, Tsung-Min; Macy, Russell; Luo, Eric C., Transdermal administration of pharmacologically active amines using hydroxide-releasing agents as permeation enhancers.
  • Hsu, Tsung-Min; Macy, Russell; Luo, Eric C., Transdermal administration of phenylpropanolamine.
  • Luo, Eric C.; Hsu, Tsung-Min, Transdermal administration of steroid drugs using hydroxide-releasing agents as permeation enhancers.
  • Fossel, Eric Thor, Transdermal delivery of beneficial substances effected by a hostile biophysical environment.
  • Svedman Pal,SEX, Transdermal device for administration through de-epithelialized skin.
  • Bello Gastone P. (Monmouth Beach NJ) Lyle John W. (Belmar NJ) Johnson Donald A. (Sea Girt NJ), Transdermal drug delivery device and method for its manufacture.
  • Russell Meri Charmyne, Treatment of equine laminitis.
  • Fossel, Eric T., Treatment of erectile dysfunction and other indications.
  • Fossel, Eric T., Treatment of erectile dysfunction and other indications.
  • Fossel, Eric T., Treatment of erectile dysfunction and other indications.
  • Garfield Robert E. ; Chwalisz Kristof,DEX, Treatment of urinary incontinence with nitric oxide synthase substrates and/or nitric oxide donors alone or in combinati.
  • Cooke John P. (Palo Alto CA) Dzau Victor J. (Los Altos Hills CA) Gibbons Gary H. (Palo Alto CA), Treatment of vascular degenerative diseases by modulation of endogenous nitric oxide production of activity.
  • Snyder Solomon H. (Baltimore MD) Burnett Arthur L. (Baltimore MD) Lowenstein Charles J. (Tacoma Park MD) Bredt David S. (Baltimore MD) Chang Thomas S. K. (Baltimore MD), Treatments for male sexual dysfunction.
  • Levere Richard D. (5 Seymour Pl. W. Armonk NY 10504) Abraham Nader G. (143 Charter Cir. Ossining NY 10562) Schwartzman Michel L. (415 Old Country Rd. Elmsford NY 10523) Martasek Pavel (60 Hillcrest R, Use of L-arginine in the treatment of hypertension and other vascular disorders.
  • Yoshimura Norman N. (Westminster CA) Barbul Adrian (Baltimore MD) Tao Robert C. (Huntington Beach CA) Storm Michael C. (Laguna Niguel CA) Kelley Robert E. (Orange CA) Reis Brenda L. (Costa Mesa CA), Use of arginine as an immunostimulator.
  • Wilcox, Christopher S., Use of nitroxides for the treatment of essential hypertension.
  • Bywater Robert J. (Surrey GB2) Dupe Robert J. (Surrey GB2), Veterinary compositions for the treatment of scours and dehydration.
  • 이 특허를 인용한 특허 (1)

    1. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
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