Integrated nanofluidic arrays for high capacity colloid separation
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
B28B-001/00
B01L-003/00
H01L-021/44
출원번호
US-0940631
(2015-11-13)
등록번호
US-9700891
(2017-07-11)
발명자
/ 주소
Smith, Joshua T.
Wunsch, Benjamin H.
Yang, Cornelia T.
출원인 / 주소
INTERNATIONAL BUSINESS MACHINES CORPORATION
대리인 / 주소
Cantor Colburn LLP
인용정보
피인용 횟수 :
0인용 특허 :
10
초록▼
A technique relates to an integrated nanofluidic device. A loading layer includes an inlet channel reservoir, a diverted fraction reservoir, and a passed fraction reservoir. A sorting layer is attached to the loading layer such that fluid is permitted to communicate between the loading and sorting l
A technique relates to an integrated nanofluidic device. A loading layer includes an inlet channel reservoir, a diverted fraction reservoir, and a passed fraction reservoir. A sorting layer is attached to the loading layer such that fluid is permitted to communicate between the loading and sorting layers, where the sorting layer includes a bank of sorting elements. The sorting layer has inlet channels and outlet channels connected to the sorting elements, and the inlet channel reservoir is connected to the inlet channels by an inlet feed hole. The diverted fraction reservoir is connected to the outlet channels by a diverted fraction outlet feed hole, and the passed fraction reservoir is connected to the sorting elements by passed fraction feed holes. The passed fraction feed holes are respectively connected to the sorting elements.
대표청구항▼
1. A method of configuring an integrated nanofluidic device, the method comprising: providing a loading layer, as a single layer, including an inlet channel reservoir, a diverted fraction reservoir, and a passed fraction reservoir; andattaching a sorting layer, as another single layer, to the loadin
1. A method of configuring an integrated nanofluidic device, the method comprising: providing a loading layer, as a single layer, including an inlet channel reservoir, a diverted fraction reservoir, and a passed fraction reservoir; andattaching a sorting layer, as another single layer, to the loading layer such that fluid is permitted to directly communicate between the loading and sorting layers, the sorting layer including a bank of sorting elements, wherein the sorting layer has inlet channels and outlet channels connected to the sorting elements, wherein the inlet channel reservoir is connected to the inlet channels by an inlet feed hole, wherein the diverted fraction reservoir is connected to the outlet channels by a diverted fraction outlet feed hole, and wherein the passed fraction reservoir is connected to the sorting elements by passed fraction feed holes, the passed fraction feed holes respectively connected to the sorting elements, wherein the loading layer and the sorting layer are directly attached to one another thereby forming two layers, wherein the inlet feed hole and the diverted fraction outlet feed hole are both in the sorting layer. 2. A method of configuring an integrated nanofluidic device, the method comprising: providing a loading layer, as a single layer, including an inlet channel reservoir, an inlet vias reservoir, a diverted fraction reservoir, and a passed fraction reservoir; andarranging a sorting layer, as another single layer, attached to the loading layer such that fluid is permitted to directly communicate between the loading and sorting layers, the sorting layer including a bank of sorting elements, wherein the sorting layer has inlet channels and outlet channels connected to the sorting elements, wherein the inlet channel reservoir is connected to the inlet channels by an inlet feed hole, wherein the diverted fraction reservoir is connected to the outlet channels by a diverted fraction outlet feed hole, wherein the passed fraction reservoir is connected to the sorting elements by passed fraction feed holes, the passed fraction feed holes respectively connected to the sorting elements, and wherein the inlet vias reservoir is connected to the sorting elements by inlet via holes, wherein the loading layer and the sorting layer are directly attached to one another thereby forming two layers, wherein the inlet feed hole and the diverted fraction outlet feed hole are both in the sorting layer. 3. The method of claim 2, wherein the sorting elements each include a nanopillar array configured to sort particles.
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이 특허에 인용된 특허 (10)
Cao,Han; Tegenfeldt,Jonas O.; Chou,Stephen; Austin,Robert H., Gradient structures interfacing microfluidics and nanofluidics, methods for fabrication and uses thereof.
Austin Robert H. (Princeton NJ) Volkmuth Wayne D. (Menlo Park MN) Rathburn Lynn C. (Ithaca NY), Microlithographic array for macromolecule and cell fractionation.
Chou, Stephen Y.; Cao, Han; Austin, Robert H.; Yu, Zhaoning; Tegenfeldt, Jonas O., Nanochannel arrays and their preparation and use for high throughput macromolecular analysis.
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