Methods of employing bone defect filling, e.g., orthopedic cements, in conjunction with hard tissue securing devices, e.g., screws, plates or rods, are provided. A feature of the subject methods is that the cement is introduced to a target bone site through a passageway of the securing device while
Methods of employing bone defect filling, e.g., orthopedic cements, in conjunction with hard tissue securing devices, e.g., screws, plates or rods, are provided. A feature of the subject methods is that the cement is introduced to a target bone site through a passageway of the securing device while a vibratory force is applied to the securing device. Also provided are systems and kits that find use in practicing the subject methods. The subject methods, devices and systems find use in a variety of different applications.
대표청구항▼
1. A system for introducing an orthopedic cement to a target bone site, said system comprising: (a) an orthopedic calcium phosphate cement composition;(b) a cannulated hard tissue securing device that comprises: an elongated body,an internal passageway through which the orthopedic calcium phosphate
1. A system for introducing an orthopedic cement to a target bone site, said system comprising: (a) an orthopedic calcium phosphate cement composition;(b) a cannulated hard tissue securing device that comprises: an elongated body,an internal passageway through which the orthopedic calcium phosphate cement composition is driven, andthreading at an end of the elongated body; and(c) a cement delivery device comprising: (i) a needle, wherein a distal end of the needle comprises threads that mate with the threading of the cannulated hard tissue securing device such that the orthopedic calcium phosphate cement composition passes through the needle and into the internal passageway of the cannulated hard tissue securing device,(ii) a needle holder that secures the needle to the cement delivery device, and(ii) a vibratory element connected to the needle holder that vibrates the needle via a pneumatically driven vibrating disc, wherein the vibration facilitates pushing the orthopedic calcium phosphate cement composition through the needle into the internal passageway of the cannulated hard tissue securing device. 2. The system according to claim 1, wherein the cannulated hard tissue securing device is a screw. 3. The system according to claim 1, wherein the cannulated hard tissue securing device is a plate. 4. The system according to claim 1, wherein the cannulated hard tissue securing device is a nail. 5. The system according to claim 1, wherein the vibration is sufficient to provide highly controlled penetration of the cement into the target bone site without use of substantial pressure. 6. The system according to claim 1, wherein the passageway is a channel bounded on all sides, with an inlet at a first end of the cannulated hard tissue securing device and an exit at a second end of the cannulated hard tissue securing device. 7. The system according to claim 1, wherein the vibration changes a shape of the cement composition after the cement composition is received into the target bone site. 8. The system according to claim 1, wherein the vibration modulates a rate of setting of the cement composition. 9. The system according to claim 8, wherein the vibration causes the cement composition to take more time to set as compared to a length of time that the cement composition would have taken to set had the vibration not been applied. 10. The system according to claim 8, wherein the vibration causes the cement composition to take less time to set as compared to a length of time that the cement composition would have taken to set had the vibration not been applied. 11. A kit comprising: (a) an orthopedic calcium phosphate cement composition;(b) a cannulated hard tissue securing device that comprises: an elongated body,an internal passageway through which the orthopedic calcium phosphate cement composition is driven, andthreading at an end of the elongated body; and(c) a cement delivery device comprising: (i) a needle, wherein a distal end of the needle comprises threads that mate with the threading of the cannulated hard tissue securing device such that the orthopedic calcium phosphate cement composition passes through the needle and into the internal passageway of the cannulated hard tissue securing device,(ii) a needle holder that secures the needle to the cement delivery device, and(ii) a vibratory element connected to the needle holder that vibrates the needle via a pneumatically driven vibrating disc, wherein the vibration facilitates pushing the orthopedic calcium phosphate cement composition through the needle into the internal passageway of the cannulated hard tissue securing device. 12. The kit according to claim 11, wherein the vibration changes a shape of the cement composition after the cement composition is received into a target bone site. 13. The kit according to claim 11, wherein the vibration modulates a rate of setting of the cement composition. 14. The kit according to claim 13, wherein the vibration causes the cement composition to take more time to set as compared to a length of time that the cement composition would have taken to set had the vibration not been applied. 15. The kit according to claim 14, wherein the vibration causes the cement composition to take less time to set as compared to a length of time that the cement composition would have taken to set had the vibration not been applied.
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