System and method for detecting worsening of heart failure based on rapid shallow breathing index
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61B-005/00
A61B-005/0205
A61B-005/113
A61B-005/08
A61B-005/091
A61B-005/085
출원번호
US-0450728
(2014-08-04)
등록번호
US-9743889
(2017-08-29)
발명자
/ 주소
Zhang, Yi
Averina, Viktoria A.
Beck, Kenneth C.
Thakur, Pramodsingh
Wariar, Ramesh
출원인 / 주소
Cardiac Pacemakers, Inc.
대리인 / 주소
Schwegman Lundberg & Woessner, P.A.
인용정보
피인용 횟수 :
0인용 특허 :
120
초록▼
Systems and methods for detecting a worsening of patient's heart failure condition based, at least in part, on an increasing trend in a representative rapid shallow breathing index (RSBI) value over multiple days. The RSBI value may be a minimum RSBI, and more particularly may be a minimum RSBI valu
Systems and methods for detecting a worsening of patient's heart failure condition based, at least in part, on an increasing trend in a representative rapid shallow breathing index (RSBI) value over multiple days. The RSBI value may be a minimum RSBI, and more particularly may be a minimum RSBI value determined for an afternoon portion of each of the multiple days. The minimum RSBI value measured during an afternoon portion of the day may be more sensitive to changes in a patient's respiration, particularly when a patient is expected to be more active, and thus, may more readily exhibit an increasing trend when patient's heart failure is in decline.
대표청구항▼
1. A system for monitoring a progression of heart failure in a patient, the system comprising: a sensor configured to provide one or more signals indicative of respiration of a patient;circuitry coupled to the sensor, the circuitry configured to: determine a plurality of respiration rate and tidal v
1. A system for monitoring a progression of heart failure in a patient, the system comprising: a sensor configured to provide one or more signals indicative of respiration of a patient;circuitry coupled to the sensor, the circuitry configured to: determine a plurality of respiration rate and tidal volume measurements during each of a plurality of twenty-four hour periods using the one or more signals indicative of the respiration of the patient;determine a rapid shallow breathing index (RSBI) value for a selected portion of each of a plurality of the twenty-four hour periods based, at least in part, on one or more of the corresponding plurality of the respiration rate and tidal volume measurements;determine a first RSBI aggregate based, at least in part, on the RSBI values that fall within a first time window having a first duration;determine a second RSBI aggregate based, at least in part, on the RSBI values that fall within a second time window having a second duration, wherein the first duration is different than the second duration;determine a relationship between the first RSBI aggregate determined for the first time window and the second RSBI aggregate determined for the second time window; andan output coupled to the circuitry for providing an output signal indicative of an HF status of the patient based, at least in part, on the determined relationship between the first RSBI aggregate determined for the first time window and the second RSBI aggregate determined for the second time window,wherein the RSBI aggregates for the selected portion of each of the plurality of twenty-four hour period are determined, in part, by a ratio between the corresponding plurality of respiration rate and tidal volume measurements, and wherein the RSRI aggregates for the selected portion of each of the plurality of twenty-four hour period are defined by a minimum or a lower percentile of the plurality of the ratios between the corresponding plurality of respiration rate measurements and the corresponding plurality of tidal volume measurements. 2. The system according to claim 1, wherein the sensor comprises at least one of an impedance sensor, a capacitance sensor, an accelerometer, a displacement sensor, an optical sensor and a pressure sensor. 3. The system according to claim 1, wherein the relationship between the first RSBI aggregate determined for the first time window and the second RSBI aggregate determined for the second time window is determined by subtracting the first RSBI aggregate determined for the first time window from the second RSBI aggregate determined for the second time window. 4. The system according to claim 1, wherein the relationship between the first RSBI aggregate determined for the first time window and the second RSBI aggregate determined for the second time window is characterized by determining a fractional difference between the first RSBI aggregate determined for the first time window and the second RSBI aggregate determined for the second time window. 5. The system according to claim 1, wherein the first duration and second duration are measured in a number of twenty-four hour periods. 6. The system according to claim 1, wherein the first time window and the second time window do not overlap. 7. The system according to claim 1, wherein the selected portion of each of the twenty-four hour periods corresponds to an afternoon portion, a morning portion, or an evening portion. 8. The system according to claim 1, wherein the selected portion of each of the twenty-four hour periods corresponds to a morning portion and an afternoon portion. 9. The system according to claim 1, wherein the selected portion of each of the twenty-four hour periods excludes a period when the patient is asleep. 10. The system according to claim 1, wherein the first and second RSBI aggregates are defined by a ratio between a minimum respiration rate and a maximum tidal volume. 11. The system according to claim 1, wherein the RSBI aggregates for the selected portion of each of the plurality of twenty-four hour period are defined by a ratio between a lower value of the corresponding plurality of respiration rate measurements and an upper value of the corresponding plurality of tidal volume measurements. 12. A system for monitoring a progression of heart failure in a patient, the system comprising: a sensor configured to detect respiration in a patient and configured to generate signals indicative of the patient's respiration over multiple twenty-four hour periods,circuitry coupled to the sensor, the circuitry configured to: determine a plurality of respiration rate and tidal volume measurements for each of multiple twenty-four hour periods using the signals indicative of the respiration of the patient;determine a representative RSBI value for a selected portion of each of the multiple twenty-four hour periods based, at least in part, on the corresponding plurality of respiration rate and tidal volume measurements;determine a first RSBI aggregate based, at least in part, on the RSBI values that fall within a first time window having a first duration;determine a second RSBI aggregate based, at least in part, on the RSBI values that fall within a second time window having a second duration, wherein the first duration is different than the second duration;determine a relationship between the first RSBI aggregate determined for the first time window and the second RSBI aggregate determined for the second time window; andan output coupled to the circuitry for providing an output signal indicative of a current heart failure status of the patient based on a change in the representative RSBI value over multiple twenty-four hour periods, wherein the RSBI aggregates for the selected portion of each of the plurality of twenty-four hour period are determined, in part, by a ratio between the corresponding plurality of respiration rate and tidal volume measurements, and wherein the RSBI aggregates for the selected portion of each of the plurality of twenty-four hour period are defined by a minimum or a lower percentile of the plurality of the ratios between the corresponding plurality of respiration rate measurements and the corresponding plurality of tidal volume measurements. 13. The system according to claim 12, wherein the circuitry is configured to determine a representative RSBI value based on a lower value of the plurality of respiration rate measurements and an upper value of plurality of tidal volume measurements for the selected portion of each of the multiple twenty-four hour periods. 14. The system according to claim 12, wherein the circuitry is configured to determine a representative RSBI value based on a lower value of a plurality of the ratios between the corresponding plurality of respiration rate measurements and the corresponding plurality of tidal volume measurements for the selected portion of each of the multiple twenty-four hour periods. 15. The system according to claim 12, wherein the change in the representative RSBI value is determined based on a difference between a long term aggregate of the representative RSBI value and a short term aggregate of the representative RSBI value. 16. The system according to claim 12, wherein the selected portion corresponds to at least one of a morning portion, an afternoon portion and an evening portion of each of the multiple twenty-four hour periods. 17. A method of determining a progression of heart failure in a patient, the method comprising: detecting respiration in a patient over multiple twenty-four hour periods using a sensor;the sensor generating signals indicative of the respiration of the patient over the multiple twenty-four hour periods;determining a plurality of respiration rate measurements and tidal volume measurements for each of the multiple twenty-four hour periods using the signals indicative of the respiration of the patient;determining a representative RSBI value for a selected portion of each of the multiple twenty-four hour periods based, at least in part, on the corresponding plurality of respiration rate measurements and tidal volume measurements;determining a first RSBI aggregate based, at least in part, on the RSBI values that fall within a first time window having a first duration;determining a second RSBI aggregate based, at least in part, on the RSBI values that fall within a second time window having a second duration, wherein the first duration is different than the second duration;determining a relationship between the first RSBI aggregate determined for the first time window and the second RSBI aggregate determined for the second time window; andgenerating an output signal indicative of a current heart failure status of the patient based on a change in the representative RSBI value over multiple twenty-four hour periods,wherein the RSBI aggregates for the selected portion of each of the plurality of twenty-four hour period are determined, in part, by a ratio between the corresponding plurality of respiration rate and tidal volume measurements, and wherein the RSBI aggregates for the selected portion of each of the plurality of twenty-four hour period are defined by a minimum or a lower percentile of the plurality of the ratios between the corresponding plurality of respiration rate measurements and the corresponding plurality of tidal volume measurements. 18. The method according to claim 17, wherein the selected portion of each of the multiple twenty-four hour periods excludes a period when the patient is asleep.
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Burnes,John E.; Cho,Yong K.; Igel,David; Mongeon,Luc R.; Rueter,John C.; Stone,Harry; Zilinski,Jodi, Algorithm for the automatic determination of optimal AV an VV intervals.
Baumann Lawrence S. ; Tockman Bruce A. ; Salo Rodney W. ; Silvermint Emanuel H., Apparatus and method for optimizing cardiac performance by determining the optimal timing interval from an acceleromete.
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Dahl Roger W. (Andover MN) Swanson David K. (Roseville MN) Hahn Stephen J. (Roseville MN) Lang Douglas J. (Arden Hills MN) Heil John E. (St. Paul MN), Body implantable defibrillation system.
Salo Rodney W. (Fridley MN) Spinelli Julio C. (Shoreview MN) Tockman Bruce A. (Minneapolis MN), Cardiac stimulating apparatus and method for heart failure therapy.
Swanson David K. (Roseville MN) Dahl Roger W. (Andover MN) Lang Douglas J. (Arden Hills MN), Defibrillation electrode system having smooth current distribution with floating electrode.
KenKnight Bruce H. (Minneapolis MN) Hall Jeffrey A. (Bloomington MN), Defibrillation patch electrode having conductor-free resilient zone for minimally invasive deployment.
Van Hofwegen Lloyd (New Brighton MN) Hsung Jean-Cheui (Shoreview MN) Huntwork Daniel (Vadnais Heights MN), Defibrillation/cardioversion system with multiple evaluation of heart condition prior to shock delivery.
Swanson David K. (Roseville MN) Nelson James P. (Shoreview MN) Lang Douglas J. (Arden Hills MN), Defibrillator waveform generator for generating waveform of long duration.
Haefner Paul A. (Crystal MN) Stockburger Mark A. (Inver Grove Heights MN) Linder William J. (Golden Valley MN), Digital AGC using separate gain control and threshold templating.
Swanson David K. (Roseville MN) Ideker Raymond E. (Durham NC) Walcott Greg (Durham NC), Dual capacitor biphasic defibrillator waveform generator employing selective connection of capacitors for each phase.
Ding,Jing; Yu,Yinghong; Spinelli,Julio, Identifying heart failure patients suitable for resynchronization therapy using QRS complex width from an intracardiac electrogram.
Combs William J. ; Condie Catherine R. ; Martin Roy ; Warkentin Dwight H. ; Wahlstrandl John D., Impedance monitor for discerning edema through evaluation of respiratory rate.
Donald L. Hopper ; Jeffrey E. Stahmann ; Bruce R. Jones ; James P. Nelson, Implantable cardiac rhythm management device for assessing status of CHF patients.
Hopper Donald L. ; Stahmann Jeffrey E. ; Jones Bruce R. ; Nelson James P., Implantable cardiac rhythm management device for assessing status of CHF patients.
Kroll Mark W. (Minnetonka MN) Adams Theodore P. (Edina MN) Anderson Kenneth M. (Bloomington MN) Smith Charles U. (Minnetonka MN), Implantable cardioverter defibrillator having a smaller displacement volume.
KenKnight Bruce H. ; Dahl Roger W. ; Swanson David K., Implantable conformal coil patch electrode with multiple conductive elements for cardioversion and defibrillation.
Hauser Robert G. (Long Lake MN), Implantable intravenous cardiac stimulation system with pulse generator housing serving as optional additional electrode.
Euljoon Park ; Gene A. Bornzin ; Joseph J. Florio ; Said Mortazavi, Implantable stimulation device having synchronous sampling for a respiration sensor.
Hahn Stephen J. (Roseville MN) Swanson David K. (Mountain View CA), Method and apparatus for defibrillation using a multiphasic truncated exponential waveform.
Tockman Bruce A. (Minneapolis MN) Spinelli Julio C. (Shoreview MN) Salo Rodney W. (Fridley MN), Method and apparatus to automatically optimize the pacing mode and pacing cycle parameters of a dual chamber pacemaker.
Ohsaki, Rie; Kimura, Teiyuu; Nanba, Shinji; Hayano, Junichiro; Shiomi, Toshiaki, Method for detecting physiological condition of sleeping patient based on analysis of pulse waves.
Dahl Roger W. (Andover MN) Swanson David K. (Roseville MN) Hahn Stephen J. (Roseville MN) Lang Douglas J. (Arden Hills MN) Heil John E. (St. Paul MN), Process for implanting subcutaneous defibrillation electrodes.
Brockway Brian P. (Minneapolis MN) Dreher Robert D. (Roseville MN) Huntwork Daniel E. (White Bear Lake MN) Lindstedt Brock S. (St. Paul MN) Morrison Douglas C. (St. Paul MN) Mills Perry A. (Roseville, Programmable multi-mode cardiac pacemaker.
Zhang, Yi; Hatlestad, John D.; Dalal, Yousufali H.; Brockway, Marina, Rapid shallow breathing detection for use in congestive heart failure status determination.
Zhang, Yi; Hatlestad, John D.; Dalal, Yousufali H.; Brockway, Marina, Rapid shallow breathing detection for use in congestive heart failure status determination.
Hauck John A. (Shoreview MN) Olive Arthur L. (Stacy MN), Rate adaptive cardiac rhythm management device control algorithm using trans-thoracic ventilation.
Webb Stuart C. (5 Lingholm Way Barnet ; Hertfordshire GBX) Lewis Leland M. (43 Prince George Avenue ; Oakwood London GBX N14 4TL) Morris-Thurgood Jayne A. (20 Pym Walk Thame ; Oxfordshire GBX), Rate-responsive pacemaker.
Heil ; Jr. Ronald W. (Roseville MN) Kenknight Bruce H. (Robbinsdale MN) Wickham ; Jr. ; deceased Robert W. (late of Harris MN) Quiggle ; legal administrator by Duane R. (Forest Lake MN), Resilient structurally coupled and electrically independent electrodes.
Pless, Benjamin D.; Archer, Stephen T.; Baysinger, Craig M.; Gibb, Barbara; Gurunathan, Suresh K.; Kirkpatrick, Bruce; Tcheng, Thomas K., Seizure sensing and detection using an implantable device.
Dahl Roger W. (Andover MN) Swanson David K. (Roseville MN) Hahn Stephen J. (Roseville MN) Lang Douglas J. (Arden Hills MN) Heil John E. (St. Paul MN), Subcutaneous defibrillation electrodes.
Dahl Roger W. (Andover MN) Swanson David K. (Roseville MN) Hahn Stephen J. (Roseville MN) Lang Douglas J. (Arden Hills MN) Heil John E. (St. Paul MN), Subcutaneous defibrillation electrodes.
Dahl Roger W. (Andover) Swanson David K. (Roseville) Hahn Stephen J. (Roseville) Lang Douglas J. (Arden Hills) Heil John E. (St. Paul MN), Subcutaneous defibrillation electrodes.
Bardy Gust H., System and method for automated collection and analysis of patient information retrieved from an implantable medical device for remote patient care.
Gust H. Bardy, System and method for automated collection and analysis of patient information retrieved from an implantable medical device for remote patient care.
Bardy Gust H., System and method for determining a reference baseline of individual patient status for use in an automated collection and analysis patient care system.
Bardy Gust H., System and method for determining a reference baseline of individual patient status for use in an automated collection and analysis patient care system.
Koh,Steve, System and method for diagnosing and tracking congestive heart failure based on the periodicity of Cheyne-Stokes Respiration using an implantable medical device.
Bardy Gust H., System and method for monitoring a patient status for an individual patient using a reference baseline in an automated collection and analysis patient care system.
Andrew P. Kramer ; Jeffrey E. Stahmann ; Rene H. Wentkowski ; Kenneth L. Baker ; Jesse W. Hartley ; David B. Krig, System providing ventricular pacing and biventricular coordination.
Kramer Andrew P. ; Stahmann Jeffrey E. ; Wentkowski Rene H. ; Baker Kenneth L. ; Hartley Jesse W. ; Krig David B., System providing ventricular pacing and biventricular coordination.
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