The invention pertains to an applicator (1) for inserting an implant, in particular a rod-like implant (2) containing an active substance, under the skin of a human or animal, comprising a housing (3), a cannula (6), a cannula holder (9), an implant (2) accommodated inside the cannula (6) and/or the
The invention pertains to an applicator (1) for inserting an implant, in particular a rod-like implant (2) containing an active substance, under the skin of a human or animal, comprising a housing (3), a cannula (6), a cannula holder (9), an implant (2) accommodated inside the cannula (6) and/or the cannula holder (9), a protective cover (7) for the cannula (6), and a mechanism (22, 23, 7) which, at least after the cover (7) has been removed from the cannula (6), secures the implant (2) inside the cannula (6) and/or cannula holder (9). The mechanism (22, 23, 7) disengages the implant (2) during insertion of the cannula (6) or after the cannula (6) has been inserted. Substantially no lateral force will be exerted during the expelling of the implant from the cannula.
대표청구항▼
1. An applicator for inserting a rod-like implant containing an active substance, under the skin of a human or animal, comprising a housing,a cannula,a cannula holder,an implant accommodated inside the cannula or the cannula holder,a protective cover for the cannula, anda mechanism,wherein the cannu
1. An applicator for inserting a rod-like implant containing an active substance, under the skin of a human or animal, comprising a housing,a cannula,a cannula holder,an implant accommodated inside the cannula or the cannula holder,a protective cover for the cannula, anda mechanism,wherein the cannula comprises a tube having a hollow interior along an axial length of the tube and terminating in an opening at an axial end of the tube,wherein the implant is slidable through the hollow tube along the axial length to exit through the opening for insertion of the implant,wherein removal of the cover causes the mechanism to engage with the implant to secure the implant inside the cannula or the cannula holder to prevent exit of the implant through the opening, wherein the mechanism disengages the implant during insertion of the cannula or after the cannula has been inserted and prior to movement of the implant with respect to the cannula for expelling the implant from the cannula. 2. The applicator according to claim 1, wherein the mechanism exerts substantially no force on the implant prior to removal of the cover and secures the implant inside the cannula upon removal of the cover. 3. The applicator according to claim 1, wherein the mechanism comprises a lever extending along at least part of the cannula, which lever is rotatable or slidable or flexible between a first position wherein the lever engages with the implant so that the implant is secured inside the cannula or the cannula holder and a second position wherein the lever is disengaged from the implant. 4. The applicator according to claim 3, wherein the cannula or the cannula holder comprises an opening which allows access to the implant, and the lever comprises a protrusion in register with this opening to protrude through the opening to engage with the implant. 5. The applicator according to claim 4, wherein the lever is biased towards the cannula or the cannula holder and urges the implant against the inner wall of the cannula or the cannula holder. 6. The applicator according to claim 3, wherein the cover, when installed, forces the lever into its second position. 7. The applicator according to claim 3, wherein the lever in its first position locks the cannula or cannula holder, and in its second position unlocks the cannula or cannula holder. 8. The applicator according to claim 7, wherein the lever comprises at least one protrusion or notch, the cannula or the cannula holder comprises respectively at least one notch or protrusion, and wherein at least one respective notch and protrusion interlock in the first position of the lever. 9. The applicator according to claim 1, comprising a rod mounted on or in the housing and at least partially inside the cannula, and an actuator for sliding the cannula and the rod relative to each other. 10. The applicator according to claim 1 received inside a sterile package. 11. The applicator according to claim 1, wherein the implant is a non-biodegradable rod measuring 40 mm in length and 2 mm in diameter and containing etonogestrel. 12. The applicator according to claim 1, further comprising a second mechanism which, if no implant is present in the cannula or the cannula holder, locks the cover to the housing. 13. The applicator according to claim 1, further comprising an actuator for retracting the cannula into the housing for expelling the implant from the opening of the cannula. 14. The applicator according to claim 1, wherein the implant contains etonogestrel. 15. An applicator for inserting a rod-like implant containing an active substance, under the skin of a human or animal, comprising a housing,a cannula,a cannula holder,an implant accommodated inside the cannula or the cannula holder,a protective cover for the cannula, anda mechanism,wherein the cannula comprises a tube having a hollow interior along an axial length of the tube and terminating in an opening at an axial end of the tube,wherein the implant is slidable through the hollow tube along the axial length to exit through the opening for insertion of the implant,wherein the mechanism, after the cover has been removed from the cannula, engages with the implant to secure the implant inside the cannula or the cannula holder to prevent exit of the implant through the opening, wherein the mechanism disengages the implant during insertion of the cannula or after the cannula has been inserted and prior to movement of the implant with respect to the cannula for expelling the implant from the cannula, andwherein the mechanism comprises a lever extending along at least part of the cannula, which lever is rotatable or slidable or flexible between a first position wherein the lever engages with the implant so that the implant is secured inside the cannula or the cannula holder and a second position wherein the lever is disengaged from the implant, andwherein the housing comprises a handle extending above at least part of the cannula and wherein, the lever is rotatably connected to the distal end of the handle. 16. A method for inserting an implant under the skin of a human or animal using an applicator: uncovering the cannula;securing the implant inside a cannula or cannula holder using a mechanism which engages the implant, after uncovering the cannula;inserting the cannula beneath the skin;disengaging the mechanism from the implant during insertion of the cannula or after the cannula has been inserted without moving the implant with respect to the cannula; andsubsequently sliding the disengaged implant along an axial length of a hollow interior of the cannula to expel the implant from an opening at an axial end of the cannula;wherein securing the implant inside the cannula or cannula holder comprises preventing exit of the implant through the opening;the method further comprising removing a cover from the cannula prior to inserting the cannula beneath the skin, whereby removal of the cover causes the mechanism to engage with the implant to secure the implant. 17. The method of claim 16, further comprising replacing the cover onto the cannula after expelling the implant, whereby replacing of the cover without an implant being present in the cannula causes locking of the cover over the cannula. 18. The method of claim 16, further comprising accommodating the implant inside the cannula or the cannula holder while exerting substantially no force on the implant prior to removal of the cover. 19. The method according to claim 16, further comprising using an actuator to retract the cannula into the housing for expelling the implant from the opening of the cannula. 20. The method according to claim 16, wherein the implant is a non-biodegradable rod measuring 40 mm in length and 2 mm in diameter and containing etonogestrel. 21. The applicator for inserting a rod-like implant containing an active substance, under the skin of a human or animal, comprising a housing,a cannula,a cannula holder,an implant accommodated inside the cannula or the cannula holder,a protective cover for the cannula, anda mechanism,wherein the cannula comprises a tube having a hollow interior along an axial length of the tube and terminating in an opening at an axial end of the tube,wherein the implant is slidable through the hollow tube along the axial length to exit through the opening for insertion of the implant,wherein the mechanism, after the cover has been removed from the cannula, engages with the implant to secure the implant inside the cannula or the cannula holder to prevent exit of the implant through the opening, wherein the mechanism disengages the implant during insertion of the cannula or after the cannula has been inserted and prior to movement of the implant with respect to the cannula for expelling the implant from the cannula, andwherein the mechanism comprises a lever extending along at least part of the cannula, which lever is rotatable or slidable or flexible between a first position wherein the lever engages with the implant so that the implant is secured inside the cannula or the cannula holder and a second position wherein the lever is disengaged from the implant, andwherein the lever is positioned so that the lever contacts the skin of the human or animal during insertion of the cannula to rotate the lever to the second position. 22. A method of contraception comprising inserting an implant containing etonogestrel under the skin of a human or animal using an applicator comprising: a housing, a cannula, a cannula holder, an implant, wherein the implant is accommodated inside the cannula or the cannula holder, a protective cover for the cannula, and a mechanism, wherein the cannula comprises a tube having a hollow interior along an axial length of the tube and terminating in an opening at an axial end of the tube, wherein the implant is slidable through the hollow tube along the axial length to exit through the opening for insertion of the implant, wherein removal of the cover causes the mechanism to engage with the implant to secure the implant inside the cannula or the cannula holder to prevent exit of the implant through the opening, wherein the mechanism disengages the implant during insertion of the cannula or after the cannula has been inserted and prior to movement of the implant with respect to the cannula for expelling the implant from the cannula. 23. The applicator according to claim 22, wherein the implant is a non-biodegradable rod measuring 40 mm in length and 2 mm in diameter. 24. The method of claim 22 wherein the mechanism comprises a lever extending along at least part of the cannula, which lever is rotatable or slidable or flexible between a first position wherein the lever engages with the implant so that the implant is secured inside the cannula or the cannula holder and a second position wherein the lever is disengaged from the implant, and wherein the housing comprises a handle extending above at least part of the cannula and wherein, the lever is rotatably connected to the distal end of the handle. 25. The method of claim 22 wherein the mechanism comprises a lever extending along at least part of the cannula, which lever is rotatable or slidable or flexible between a first position wherein the lever engages with the implant so that the implant is secured inside the cannula or the cannula holder and a second position wherein the lever is disengaged from the implant, and wherein the lever is positioned so that the lever contacts the skin of the human or animal during insertion of the cannula to rotate the lever to the second position.
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이 특허에 인용된 특허 (13)
Schlegel Karl-Heinz,DEX ; Feit Herbert,DEX, Cannula for the subcutaneous deposition of an object.
Beelen, Dennis Cornelis Franciscus; Van Harmelen, Martin; Moormann, Robertus Theodoor Maria; Tak, Maurice Petrus Wilhelmus, Kit for and method of assembling an applicator for inserting an implant.
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