This invention is directed to an assembled implant comprising two or more portions of bone that are held together in appropriate juxtaposition with one or more biocompatible pins to form a graft unit. Preferably, the pins are cortical bone pins. Typically, the cortical pins are press-fitted into app
This invention is directed to an assembled implant comprising two or more portions of bone that are held together in appropriate juxtaposition with one or more biocompatible pins to form a graft unit. Preferably, the pins are cortical bone pins. Typically, the cortical pins are press-fitted into appropriately sized holes in the bone portions to achieve an interference fit. The bone portions are allograft or xenograft.
대표청구항▼
1. An assembled bone graft, said assembled bone graft assembled outside the body and suitable for implantation into a human patient, said assembled bone graft comprising: (a) two machined allograft bone pieces and an internal piece, wherein:i) said machined allograft bone pieces comprise cortical bo
1. An assembled bone graft, said assembled bone graft assembled outside the body and suitable for implantation into a human patient, said assembled bone graft comprising: (a) two machined allograft bone pieces and an internal piece, wherein:i) said machined allograft bone pieces comprise cortical bone;ii) said internal piece comprises osteogenic material;iii) patterned external grooves or teeth that are machined into superior and inferior surfaces of the graft and traverse each of said machined allograft bone pieces; and(b) biocompatible pins consisting essentially of cortical bone, wherein each biocompatible pin completely traverses said graft for holding said graft together as an assembled bone graft; andwherein said two machined allograft bone pieces have drilled holes that completely traverse said two machined allograft bone pieces, and said biocompatible pins are press-fit in said drilled holes across the entire length of said drilled holes. 2. The graft of claim 1 wherein two biocompatible pins are used. 3. The graft of claim 1 wherein the interface between said two machined allograft bone pieces is substantially planar. 4. The graft of claim 1 wherein said osteogenic material comprises allograft bone, autograft bone, demineralized bone, bone powder, bone derivatives, bone morphogenetic protein, antibiotics, bioactive glass, hydroxyapatite, bioactive ceramics, or combinations thereof. 5. An assembled bone graft comprising machined allograft bone having a substantially “D”-shaped external profile, wherein said assembled bone graft is made from stacked machined allograft bone pieces; wherein said stacked machined allograft bone pieces comprise substantially planar faces that are substantially parallel to each other; andwherein said stacked machined allograft bone pieces are stacked on top of or adjacent to each other and are pinned to each other using biocompatible pins; andwherein said machined allograft bone pieces have drilled holes that completely traverse said machined allograft bone pieces, and said biocompatible pins are press-fit in said drilled holes across the entire length of said drilled holes; and wherein said biocompatible pins consist essentially of cortical bone, and each biocompatible pin completely traverses said graft, holding said graft together as an assembled bone graft. 6. An assembled bone graft comprising machined allograft bone having a substantially “D”-shaped external profile, wherein said assembled bone graft is made from two machined allograft cortical bone pieces and wherein said machined allograft cortical bone pieces comprise: i) a substantially straight rear wallii) a substantially straight side wall; andiii) a curved front walland further wherein said machined allograft bone pieces are stacked on top of or adjacent to each other to form said assembled bone graft; andwherein said machined allograft bone pieces are held together utilizing biocompatible pins and said machined allograft bone pieces have drilled holes that completely traverse said machined allograft bone pieces, and said biocompatible pins are press-fit in said drilled holes across the entire length of said drilled holes; and wherein said biocompatible pins consist essentially of cortical bone, and each biocompatible pin completely traverses said graft, holding said graft together as an assembled bone graft. 7. The graft of claim 1, wherein said biocompatible pins are impelled through each piece of said assembled bone graft such that the implants are formed into a unitary body by said biocompatible pins. 8. The graft of claim 5, wherein said biocompatible pins are impelled through each of said machined allograft bone pieces such that the implants are formed into a unitary body by said biocompatible pins. 9. The graft of claim 6, wherein said biocompatible pins are impelled through each piece of said assembled bone graft such that the implants are formed into a unitary body by said biocompatible pins. 10. The graft of claim 6, wherein said machined allograft bone pieces comprise two mirror image halves of a desired shape. 11. The graft of claim 6, further comprising patterned external grooves or teeth that are machined into superior and inferior surf aces of the graft and traverse each of said machined allograft bone pieces. 12. An assembled bone graft comprising machined allograft bone, wherein said assembled bone graft is made from stacked machined allograft bone pieces; wherein said stacked machined allograft bone pieces comprise substantially planar faces that are substantially parallel to each other; andwherein said stacked machined allograft bone pieces are stacked on top of or adjacent to each other and are pinned to each other using biocompatible pins; and wherein said machined allograft bone pieces comprise discontinuous walls consisting substantially of cortical bone and wherein said discontinuous walls comprise mirror image halves which, in combination, comprise the shape of the graft; andwherein said machined allograft bone pieces have drilled holes that completely traverse said machined allograft bone pieces, and said biocompatible pins are press-fit in said drilled holes across the entire length of said drilled holes; and wherein said biocompatible pins consist essentially of cortical bone, and each biocompatible pin completely traverses said graft, holding said graft together as an assembled bone graft. 13. An implant comprising at least two shaped cortical bone implants stacked on top of or adjacent to each other, wherein said shaped cortical bone implants are adapted to form a unitary implant for implantation into an appropriately dimensioned cavity formed between adjacent vertebrae and wherein said at least two cortical bone implants are pinned to each other by cortical bone pins; and wherein said shaped cortical bone implants have drilled holes that completely traverse said shaped cortical bone implants, and said cortical bone pins are press-fit in said drilled holes across the entire length of said shaped cortical bone implants; and wherein each said cortical bone pins completely traverses said implant, holding said implant together. 14. The graft of claim 13, wherein said cortical bone pins are impelled through each piece of said shaped cortical bone implants such that the final implant is formed into a unitary body by said biocompatible pins. 15. The implant of claim 13, wherein said shaped cortical bone implants are two mirror image halves of a desired shape. 16. The implant of claim 13, wherein a single unitary implant composed of said shaped cortical bone implants can be produced having a desired height.
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