[특허]Antimicrobial coatings for medical devices and processes for preparing such coatings

Antimicrobial coatings for medical devices and processes for preparing such coatings 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	A61L-029/08 A61L-029/16 A61L-027/34 A61L-027/54 A61L-031/10 A61L-031/16 A61L-017/14
출원번호	US-0567183 (2014-12-11)
등록번호	US-9789228 (2017-10-17)
발명자 / 주소	Tramontano, Valentino J. Marsden, Brent Almeida, Robert F. Dahl, Eric W. Rawlins, James W. Mendon, Sharathkumar K.
출원인 / 주소	Covidien LP
대리인 / 주소	Collier, Kenneth
인용정보	피인용 횟수 : 0 인용 특허 : 100

초록 ▼

Antimicrobial formulations and coatings for medical devices and processes therefor are disclosed. The formulations include at least one water permeable polymer with at least one antimicrobial agent in a liquid medium and are prepared by wet milling the components and can form antimicrobial coatings

대표청구항 ▼

1. A process of forming an antimicrobial formulation for coating a medical device, the process comprising milling at least one water permeable polymer which is dissolved in a liquid medium with at least one antimicrobial agent which is insoluble in the liquid medium to form the antimicrobial formulation in which the at least one water permeable polymer encapsulates the at least one antimicrobial agent; and adding a primary C1-6 alcohol to the antimicrobial formulation; wherein the at least one antimicrobial agent includes a silver-based antimicrobial agent and wherein the at least one water permeable polymer includes at least one of a polyurethane or a thermoplastic polyurethane elastomer. 2. The process of claim 1, wherein the at least one water permeable polymer has a weight average molecular weight of from about 70,000 to about 120,000 Daltons. 3. The process of claim 1, wherein the at least one antimicrobial agent includes the silver-based antimicrobial agent and a second antimicrobial agent which is a polybiguanide or salt thereof. 4. The process of claim 1, wherein the at least one antimicrobial agent includes silver sulfadiazine, as the silver-based antimicrobial agent, and a second antimicrobial agent which is chlorhexidine diacetate. 5. The process of claim 1, wherein the liquid medium includes one or more of an alcohol; an ether; a ketone; an organic acid; an organic ester; an amide; a hydrocarbon; or a halogenated solvent or liquid. 6. The process of claim 1, wherein the liquid medium includes an ether and a primary C1-6 alcohol. 7. The process of claim 1, wherein the at least one antimicrobial agent is insoluble in the formulation and the formulation is milled until the insoluble antimicrobial agent has a mean particle size of no greater than 50 microns. 8. The process of claim 1, comprising initially preparing a polymer solution having a viscosity of from about 100 centipoise (cP) to about 1000 cP by dissolving the at least one water permeable polymer in the liquid medium and then adding the antimicrobial agent to the solution followed by milling the formulation. 9. The process of claim 8, further comprising adding a second antimicrobial agent to the formulation after milling, and further milling the formulation with the second antimicrobial agent. 10. The process of claim 9, wherein the primary C1-6 alcohol is methanol, ethanol, n-propanol, n-butanol, n-pentanol, and/or n-hexanol. 11. A process of forming an antimicrobial coating on a medical device, the process comprising: applying the antimicrobial formulation of claim 1 on a medical device to form an antimicrobial coating on the medical device. 12. The process of claim 11, wherein the medical device is selected from the group consisting of a dialysis catheter, a urological catheter, an enteral feeding tube, a surgical staple, a trocar, an implant, suture, a respiratory tube, a surgical plate, a surgical screw, a wire, and a hernia mesh. 13. The process of claim 11, wherein the coating has a thickness of between about 20 microns to about 80 microns. 14. The process of claim 11, wherein applying the formulation on the medical device comprises dip-coating the medical device in the formulation and then drying the antimicrobial formulation by driving off the liquid medium to form the antimicrobial coating on the medical device. 15. The process of claim 11, wherein the at least one antimicrobial agent includes a combination of silver sulfadiazine and chlorhexidine diacetate.

이 특허에 인용된 특허 (100)

Morris, Grayson; Atladottir, Svava Maria; Pienknagura, Carla, Abluminal stent coating apparatus and method using a brush assembly.
상세보기
Pacetti, Stephen Dirk; DesNoyer, Jessica; Chen, Yung Ming; Kleiner, Lothar; Hossainy, Syed F. A., Abluminal, multilayer coating constructs for drug-delivery stents.
상세보기
Solomon Donald D. (Spring Valley OH) Byron M. Parke (Centerville OH), Anti-infective and antithrombogenic medical articles and method for their preparation.
상세보기
Burrell Robert E.,CAX ; Morris Larry Roy,CAX, Anti-microbial coating for medical devices.
상세보기
Marchant Roger E. (Cleveland OH), Anticoagulant plasma polymer-modified substrate.
상세보기
Darouiche Rabih O. ; Raad Issam, Antimicrobial impregnated catheters and other medical implants.
상세보기
Chen, Yung Ming; Tang, Fuh Wei, Apparatus and method for electrostatic coating of an abluminal stent surface.
상세보기
Goicoechea George,BSX ; Mialhe Claude,FRX ; Hudson John,GBX ; Cragg Andrew H. ; Dake Michael D., Bifurcated endoluminal prosthesis.
상세보기
MacGregor David C. (Miami FL), Bifurcating stent apparatus and method.
상세보기
Cottone, Robert J., Bioabsorbable medical device with coating.
상세보기
Subramaniam Raj (Fremont CA), Biocompatible coating, medical device using the same and methods.
상세보기
Guire Patrick (Eden Prairie MN) Dunkirk Shawn G. (Eden Prairie MN), Biomolecule attachment to hydrophobic surfaces.
상세보기
Wang Lixiao (Minneapolis MN) Vickerman Linda J. (Anoka MN), Catheter balloon with retraction coating.
상세보기
Mayer David W., Clad composite stent.
상세보기
Van Sciver, Jason; Gada, Manish; Madriaga, Jessie, Clamp mandrel fixture and a method of using the same to minimize coating defects.
상세보기
Van Sciver, Jason; Gada, Manish; Madriaga, Jessie, Clamp mandrel fixture and a method of using the same to minimize coating defects.
상세보기
Fearnot Neal E. (West Lafayette IN) Kozma Thomas G. (West Lafayette IN) Ragheb Anthony O. (West Lafayette IN) Voorhees William D. (West Lafayette IN), Coated implantable medical device.
상세보기
Ragheb Anthony O. ; Bates Brian L. ; Fearnot Neal E. ; Kozma Thomas G. ; Voorhees ; III William D., Coated implantable medical device.
상세보기
Dang Mai Huong ; Chiu Phillip, Coating having biological activity and medical implant having surface carrying the same and method.
상세보기
Okuda Yasuhiro (Osaka JPX), Composite artificial blood vessel.
상세보기
Leon V. Rudakov ; Mir A. Imran ; Linh Dinh ; Ara Davidian ; Kevin T. Larkin, Composite expandable device with impervious polymeric covering and bioactive coating thereon, delivery apparatus and method.
상세보기
Von Oepen Randolf,DEX, Coronary stent.
상세보기
Bley Robert S. (Menlo Park CA) Van Bladel Kevin H. (Mountain View CA) Thomas Joseph R. (San Carlos CA), Covered expanding mesh stent.
상세보기
Ding Ni ; Helmus Michael N., Drug release stent coating process.
상세보기
Bynon Anne Nina (Tolleson AZ) Cundy Sandra M. (Mesa AZ) Kowligi Rajagopal R. (Phoenix AZ), Dual supported intraluminal graft.
상세보기
Pham Pete P. (Fremont CA) Doan Hong (Santa Clara CA) Sepetka Ivan (Los Altos CA) Eder Joseph (Los Altos CA) Snyder Edward (San Jose CA), Electrolytically severable joint for endovascular embolic devices.
상세보기
Imran Mir A., Expandable stent having radiopaque marker and method.
상세보기
Lau Lilip ; Hartigan William M. ; Frantzen John J., Expandable stents.
상세보기
Dereume Jean-Pierre Georges Emile,BEX ; MacGregor David C. ; Pinchuk Leonard, Expandable supportive endoluminal grafts.
상세보기
Dinh Linh A. ; Phan Loc X. ; Eury Robert ; Pomerantseva Irina ; Froix Michael, Expandable unit cell and intraluminal stent.
상세보기
Kanesaka Nozomu ; Tashji George A., Flexible stent with effective strut and connector patterns.
상세보기
Alt Eckhard,DEX ; Fliedner Thilo,DEX ; Alter Robert,DEX ; Stemberger Axel,DEX, Implantable vascular and endoluminal stents and process of fabricating the same.
상세보기
Andersen Erik (Roskilde DKX), In situ apparatus for generating an electrical current in a biological environment.
상세보기
Modak Shanta (River Edge NJ) Sampath Lester (Nyack NY), Infection resistant medical devices.
상세보기
Luthra, Ajay Kumar; Sandhu, Shivpal Singh, Infection resistant polymers, their preparation and uses.
상세보기
Fox ; Jr. Charles L. (New York NY) Modak Shanta M. (River Edge NJ) Sampath Lester A. (Nyack NY), Infection-resistant compositions, medical devices and surfaces and methods for preparing and using same.
상세보기
Fox ; Jr. Charles L. (New York NY) Modak Shanta M. (River Edge NJ) Sampath Lester A. (Nyack NY), Infection-resistant compositions, medical devices and surfaces and methods for preparing and using same.
상세보기
Berg Eric P. (Plymouth MN) Tuch Ronald J. (Plymouth MN) Dror Michael (Edina MN) Wolff Rodney G. (Minnetonka Beach MN), Intravascular stent and method.
상세보기
Tuch Ronald J. (Plymouth MN), Intravascular stent and method.
상세보기
Milder Fredric L. (Brookline MA), Iontophoretic structure for medical devices.
상세보기
Zhang, Zheng; Huval, Chad; O'Shaughnessey, William Shannan; Hencke, Michael; Squier, Trevor; Li, Jun; Bouchard, Michael; Loose, Christopher R., Layered non-fouling, antimicrobial antithrombogenic coatings.
상세보기
Dereume Jean-Pierre Georges Emile (Brussels BEX), Luminal graft endoprostheses and manufacture thereof.
상세보기
Zhong Sheng-ping ; Tsukernik Vladimir B., Medical device coating methods and devices.
상세보기
Zhong Sheng-ping ; Tsukernik Vladimir B., Medical device coating methods and devices.
상세보기
Hendriks Marc,NLX ; Verhoeven Michel,NLX ; Cahalan Linda L.,NLX ; Cahalan Patrick T.,NLX ; Fouache Benedicte,NLX, Medical device with biomolecule-coated surface graft matrix.
상세보기
Narciso ; Jr. Hugh L. (Santa Barbara CA), Medicament dispensing stent for prevention of restenosis of a blood vessel.
상세보기
Chappa, Ralph A., Method and apparatus for coating of substrates.
상세보기
Chappa, Ralph A., Method and apparatus for coating of substrates.
상세보기
Chappa, Ralph A., Method and apparatus for coating of substrates.
상세보기
Klein Enrique J. ; Kaplan Aaron V. ; Clifford Mark ; Overbeek-Bloem Martin, Method and apparatus for intraluminal prosthesis delivery.
상세보기
Keogh James R., Method for covalent attachment of biomolecules to surfaces of medical devices.
상세보기
Griffin ; III Joseph C. ; Jenkins David A., Method for forming an electrophysiology catheter.
상세보기
Fox, Jason; Harold, Nathan; Templin, Barry; Tochterman, Andrew, Method for selectively coating surfaces of a stent.
상세보기
Atladottir, Svava Maria; Gale, David C.; Kleine, Klaus, Method of manufacturing an implantable polymeric medical device.
상세보기
Yan,John Y.; Chan,Randy, Method of reducing or eliminating thrombus formation.
상세보기
Pacetti, Stephen D.; Moein, Mohammed E., Method of using a mandrel to coat a stent.
상세보기
Lukic Goran (Blach CHX), Methods for applying an elastic coating layer on stents.
상세보기
Fredrickson, Gerald; Pham, Lan; Schwarz, Marlene; Robida, Todd, Methods for coating workpieces.
상세보기
Terry, Richard N., Microbe-resistant medical device, microbe-resistant polymeric coating and methods for producing same.
상세보기
Dayton Michael P. (14802 Hadleigh Way Tampa FL 33624), Minimally invasive bioactivated endoprosthesis for vessel repair.
상세보기
Fischell Robert E. (14600 Viburnum Dr. Dayton MD 21036) Fischell David R. (71 Riverlawn Dr. Fair Haven NJ 07704) Fischell Tim A. (1018 Chancery Dr. Nashville TN 37215), Multi-cell stent with cells having differing characteristics.
상세보기
Roubin Gary S. ; White Geoffrey Hamilton,AUX ; Iyer Sriram S. ; Redmond Russell J. ; Vidal Claude A., Non-foreshortening intraluminal prosthesis.
상세보기
Hoffman Allan S. (King County WA) Garfinkle Andrew (King County WA) Ratner Buddy D. (King County WA) Hanson Stephen R. (San Diego County CA), Plasma gas discharge treatment for improving the biocompatibility of biomaterials.
상세보기
Hoffman Allan S. (4528 W. Laurel Dr. ; N.E. ; Seattle WA 98105) Patel Anilbhai S. (4202 Brownwood La. Arlington TX 76017) Llanos Gerard (2625 Cockrell Ave. Fort Worth TX 76109), Polyethylene oxide coated intraocular lens.
상세보기
Ludwig, Florian N.; Stankus, John; Trollsas, Mikael, Polymer for creating hemocompatible surface.
상세보기
Loeffler Joseph P., Polymer-coated stent structure.
상세보기
Tang, Yiwen; Pacetti, Stephen D.; Lin, Qing; Ding, Ni, Purification of polymers for coating applications.
상세보기
Berry Dale T. ; Herald Coy M. ; Bates Brian L. ; Boatman Scott E. ; Hoffa Michael C. ; Fearnot Neal E. ; Voorhees ; III William D., Radially expandable stent.
상세보기
Narayanan Pallassana V. (Davie FL) Stanley Kimberly D. (Florida City FL), Radiofrequency plasma treated polymeric surfaces having immobilized anti-thrombogenic agents.
상세보기
Narayanan Pallassana V. (Davie FL) Stanley Kimberly D. (Florida City FL), Radiofrequency plasma treated polymeric surfaces having immobilized anti-thrombogenic agents.
상세보기
Sundar, Rangarajan, Reflowed drug-polymer coated stent and method thereof.
상세보기
Case, Brian C.; Agnew, Charles W., Removable covering for implantable frame projections.
상세보기
Van Sciver, Jason, Rotatable support elements for stents.
상세보기
Hossainy,Syed F. A.; Mirzaee,Daryush, Selective coating of medical devices.
상세보기
Goicoechea George,BSX, Self-expanding endoluminal prosthesis.
상세보기
Ragheb Anthony O. ; Bates Brian L. ; Fearnot Neal E. ; Osborne Thomas A. ; Kozma Thomas G. ; Roberts Joseph W. ; Voorhees ; III William D., Silver implantable medical device.
상세보기
Margraf Harry W. (Clayton MO), Siver-heparin-allantoin complex.
상세보기
Lorentzen Cornelius Linda R. ; Bauermeister Katherine M., Stent delivery system.
상세보기
Dusbabek Andrew J. ; Ellis Louis G. ; Larson Christopher R. ; Brown Terry V. ; Euteneuer Charles L. ; Mertens Steven P. ; Mattison Richard C. ; Blaeser David J. ; Lorentzen Cornelius Linda R. ; Willa, Stent delivery system having stent securement apparatus.
상세보기
Dusbabek, Andrew J.; Ellis, Louis G.; Larson, Christopher R.; Brown, Terry V.; Euteneuer, Charles L.; Mertens, Steven P.; Mattison, Richard C.; Blaeser, David J.; Lorentzen Cornelius, Linda R.; Willa, Stent delivery system having stent securement apparatus.
상세보기
Chen, Yung-Ming; Bradshaw, Allan; Foreman, Philip C.; Teaby, Greg, Stent fixture and method for reducing coating defects.
상세보기
Harold, Nathan; Garcia, Antonio; Tochterman, Andrew, Stent fixture having rounded support structures and method for use thereof.
상세보기
Thompson Paul J. ; Du George W., Stent graft with braided polymeric sleeve.
상세보기
Lafontaine Daniel M. (Plymouth MN) Hastings Roger N. (Maple Grove MN), Stent locating device.
상세보기
Fox, Jason; Harold, Nathan; Templin, Barry; Tochterman, Andrew, Stent mandrel fixture and method for selectively coating surfaces of a stent.
상세보기
Fox,Jason; Harold,Nathan; Templin,Barry; Tochterman,Andrew, Stent mandrel fixture and method for selectively coating surfaces of a stent.
상세보기
Pacetti,Stephen D.; Villareal,Plaridel K., Stent mounting assembly and a method of using the same to coat a stent.
상세보기
Buirge Andrew W. (Minnepaolis MN) Buscemi Paul J. (Long Lake MN) Burmeister Paul H. (Maple Grove MN), Stent with collagen.
상세보기
Imran Mir A., Stent with silver coating and method.
상세보기
Frantzen John J., Surgical stent featuring radiopaque markers.
상세보기
Bhatnagar Rajendra S., Synthetic compounds and compositions with enhanced cell binding.
상세보기
Pacetti, Stephen D.; Le, Hung Manh, System and method for coating a tubular implantable medical device.
상세보기
Chen, Yung Ming; Ho, Henjen, System and method for coating an implantable medical device.
상세보기
Modak, Shanta M.; Sampath, Lester A., Triclosan-containing medical devices.
상세보기
DeLaurentis Mark (Ocean Springs MS) Pourrezaei Kambiz (Dresher PA) Boxman Raymond L. (Herzliya NJ ILX) Beard Richard B. (Atco NJ), Urinary catheter and system.
상세보기
Ortiz, John; Molaei, Masoud; Musbach, Frank; Gerberding, Brent C., Variable density braid stent.
상세보기
Alt Eckhard,DEX, Vascular and endoluminal stents.
상세보기
Winston Thomas R. (Leawood KS) Neet John M. (Shawnee KS), Vascular graft bypass apparatus.
상세보기
Trescony Paul V. (Robbinsdale MN) Cahalan Patrick (Stein MN NLX) Keeney Kenneth (Forest Lake MN), Vascular prosthesis and method.
상세보기
Patnaik Birendra K. ; Lin Horng-Ban ; Lentz David J. ; Zdrahala Richard J., ePTFE small caliber vascular grafts with significant patency enhancement via a surface coating which contains covalently bonded heparin.
상세보기

IPC	Description
A	생활필수품
A62	인명구조; 소방(사다리 E06C)
A62B	인명구조용의 기구, 장치 또는 방법(특히 의료용에 사용되는 밸브 A61M 39/00; 특히 물에서 쓰이는 인명구조 장치 또는 방법 B63C 9/00; 잠수장비 B63C 11/00; 특히 항공기에 쓰는 것, 예. 낙하산, 투출좌석 B64D; 특히 광산에서 쓰이는 구조장치 E21F 11/00)
A62B-1/08	.. 윈치 또는 풀리에 제동기구가 있는 것

내보내기 구분	파일저장 인쇄 메일전송
구성항목	기본정보 상세정보 관리번호, 국가코드, 자료구분, 상태, 출원번호, 출원일자, 공개번호, 공개일자, 등록번호, 등록일자, 발명명칭(한글), 발명명칭(영문), 출원인(한글), 출원인(영문), 출원인코드, 대표IPC 관리번호, 국가코드, 자료구분, 상태, 출원번호, 출원일자, 공개번호, 공개일자, 공고번호, 공고일자, 등록번호, 등록일자, 발명명칭(한글), 발명명칭(영문), 출원인(한글), 출원인(영문), 출원인코드, 대표출원인, 출원인국적, 출원인주소, 발명자, 발명자E, 발명자코드, 발명자주소, 발명자 우편번호, 발명자국적, 대표IPC, IPC코드, 요약, 미국특허분류, 대리인주소, 대리인코드, 대리인(한글), 대리인(영문), 국제공개일자, 국제공개번호, 국제출원일자, 국제출원번호, 우선권, 우선권주장일, 우선권국가, 우선권출원번호, 원출원일자, 원출원번호, 지정국, Citing Patents, Cited Patents
저장형식	Text(ASCII format) Excel format PIAS분석(.xls)
메일정보	받는사람 (필수) @ 보내는사람 (선택) @ 제목 내용 KISTI 검색결과 이메일 서비스
안내	총 건의 자료가 검색되었습니다. 다운받으실 자료의 인덱스를 입력하세요. (1-10,000) 검색결과의 순서대로 최대 10,000건 까지 다운로드가 가능합니다. 데이타가 많을 경우 속도가 느려질 수 있습니다.(최대 2~3분 소요) 다운로드 파일은 UTF-8 형태로 저장됩니다. 파일의 내용이 제대로 보이지 않을실 때는 웹브라우저 상단의 보기 -> 인코딩 -> 자동선택 여부를 확인하십시오. ~ Text(ASCII format) Excel format

연합인증

Antimicrobial coatings for medical devices and processes for preparing such coatings 원문보기

초록 ▼

대표청구항 ▼

연구과제 타임라인

이 특허에 인용된 특허 (100)

관련 콘텐츠

특허 원문 보기

IPC 상위 출원인

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

선택된 텍스트

연합인증

Antimicrobial coatings for medical devices and processes for preparing such coatings 원문보기

초록 ▼

대표청구항 ▼

연구과제 타임라인

전체(0) 논문(0) 특허(0) 보고서(0)

전체(0) 논문(0) 특허(0) 보고서(0)

이 특허에 인용된 특허 (100)

관련 콘텐츠

특허 원문 보기

IPC 상위 출원인

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

선택된 텍스트