A system, device and method are presented for utilizing stretchable active integrated circuits with inflatable bodies. The invention allows for such operative features to come into direct contact with body structures, such as the inner wall of a lumen. Such direct contact increases accuracy of measu
A system, device and method are presented for utilizing stretchable active integrated circuits with inflatable bodies. The invention allows for such operative features to come into direct contact with body structures, such as the inner wall of a lumen. Such direct contact increases accuracy of measurement and delivery of therapy.
대표청구항▼
1. A method to detect parameters inside of a lumen comprising: inserting an inflatable body into said lumen, said inflatable body having a stretchable surface and a stretchable electronic circuit affixed thereto, said stretchable surface having soft or elastic properties enabling the stretchable sur
1. A method to detect parameters inside of a lumen comprising: inserting an inflatable body into said lumen, said inflatable body having a stretchable surface and a stretchable electronic circuit affixed thereto, said stretchable surface having soft or elastic properties enabling the stretchable surface to be made longer or wider without tearing or breaking, said stretchable electronic circuit being embedded in or affixed to the stretchable surface, the stretchable electronic circuit comprising: a plurality of discrete operative devices arranged as device islands on the stretchable surface, the plurality of discrete operative devices including at least one discrete operative device and at least one other discrete operative device; anda plurality of stretchable interconnects embedded in or affixed to the stretchable surface to electrically interconnect at least some of the plurality of discrete operative devices, wherein at least one stretchable interconnect of the plurality of stretchable interconnects is directly attached to the at least one discrete operative device and to the at least one other discrete operative device to directly electrically interconnect the at least one discrete operative device to the at least one other discrete operative device;inflating the inserted inflatable body to contact the at least one discrete operative device, the at least one other discrete operative device, or a combination thereof to said lumen; andmeasuring a parameter of said lumen in response to the contact. 2. The method of claim 1, further comprising providing a therapy to the lumen based on said measured parameter. 3. The method of claim 1, further comprising generating a graphical output based on said measured parameter. 4. The method of claim 3, wherein the graphical output is a map of the lumen. 5. The method of claim 1, wherein the at least one discrete operative device and the at least one other discrete operative device detect data related to the lumen. 6. The method of claim 5, wherein said data is related to electrical conductivity of plaque inside of the lumen. 7. The method of claim 5, wherein said data is related to pH. 8. The method of claim 5, wherein said data is related to enzymatic activity. 9. The method of claim 5, wherein said data is related to chemical activity. 10. The method of claim 5, further comprising continuously generating said data from the at least one discrete operative device and the at least one other discrete operative device. 11. The method of claim 10, further comprising continuously recording said data generated by the at least one discrete operative device and the at least one other discrete operative device. 12. The method of claim 1, wherein each stretchable interconnect of the plurality of stretchable interconnects is directly attached to respective discrete operative devices of the plurality of discrete operative devices to directly electrically interconnect the plurality of discrete operative devices. 13. The method of claim 2, wherein at least one discrete operative device of the plurality of discrete operative devices comprises a drug delivery polymer comprising a drug. 14. The method of claim 13, further comprising activating the at least one discrete operative device comprising the drug delivery polymer to deliver the drug and provide the therapy to the lumen. 15. The method of claim 14, wherein the drug is an anti-inflammatory drug. 16. The method of claim 1, wherein the measured parameter is temperature data. 17. The method of claim 16, further comprising: receiving, at a processor, the temperature data; andgenerating, by the processor, a spatial temperature map of the lumen based on the temperature data. 18. The method of claim 17, further comprising: causing, by the processor, an outputting of the temperature map to a display associated with the inflatable body. 19. The method of claim 1, wherein the plurality of discrete operative devices includes an amplifier, a semiconductor structure, a transducer, a photodetector, an ultrasound emitter, a light emitting device, a capacitance sensor, a piezo-electric sensor, a temperature sensor, or a combination thereof. 20. The method of claim 1, wherein the inflatable body is expandable. 21. The method of claim 1, wherein the plurality of discrete operative devices include a plurality of temperature sensors, the method further comprising: taking a plurality of temperature measurements via the plurality of temperature sensors at multiple contact points on the lumen; andprocessing the plurality of temperature measurements to produce a spatial temperature map of the lumen, the spatial temperature map indicating plaque on the lumen. 22. The method of claim 21, further comprising: determining a plaque type, a location of the plaque, or a combination thereof based on the spatial temperature map. 23. The method of claim 22, further comprising: activating one or more drug-delivery devices of the plurality of discrete operative devices to release one or more chemical agents in response to the determined plaque type, the location of the plaque, or a combination thereof. 24. The method of claim 23, wherein a subset of the one or more drug-delivery devices are activated, the subset corresponding to the location of the plaque. 25. The method of claim 23, wherein the one or more chemical agents include one or more anti-inflammatory drugs, one or more drug delivery polymers, or a combination thereof. 26. The method of claim 25, wherein the plurality of discrete operative devices include a plurality of light emitting devices, the method further comprising: emitting light from the plurality of light emitting devices to activate the one or more released drug delivery polymers. 27. The method of claim 1, further comprising: generating a graphical tactile image map of surface contours of the lumen based on the measured parameter to detect plaque within the lumen. 28. The method of claim 27, wherein the at least one discrete operative device and the at least one other discrete operative device are a pressure sensors, and the measured parameter is a pressure measurement. 29. The method of claim 6, further comprising determining whether the plaque inside the lumen is vulnerable based on the data.
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