Devices for altering the flow of air in a respiratory cavity such as the nostrils of the nose. These methods and devices may be useful for affecting a physiologic benefit in patients suffering from a variety of medical disorders, including snoring and sleep apnea. The devices are typically removable
Devices for altering the flow of air in a respiratory cavity such as the nostrils of the nose. These methods and devices may be useful for affecting a physiologic benefit in patients suffering from a variety of medical disorders, including snoring and sleep apnea. The devices are typically removable devices that may be placed in both nostrils to increase resistance to airflow within the respiratory cavity. Resistance to expiration may be selectively increased relative to inspiration. The nasal devices may also increases patency of the nares. Any of these devices may be configured to achieve positive end-expiratory pressure (PEEP) in a subject wearing the device.
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1. A whole-nose nasal respiratory device configured to engage both of a subject's nostrils, the device comprising: a first holdfast comprising a first rim forming a first passageway;a first airflow resistor within the first passageway, the first airflow resistor comprising a first flap valve that in
1. A whole-nose nasal respiratory device configured to engage both of a subject's nostrils, the device comprising: a first holdfast comprising a first rim forming a first passageway;a first airflow resistor within the first passageway, the first airflow resistor comprising a first flap valve that inhibits exhalation through a first nostril more than inhalation through the first nostril when the first holdfast is worn in the first nostril;a second holdfast comprising a second rim forming a second passageway;a second airflow resistor within the second passageway, the second airflow resistor comprising a second flap valve that inhibits exhalation through a second nostril more than inhalation through the second nostril when the second holdfast is worn in the second nostril; anda connector connecting the first rim to the second rim. 2. The device of claim 1, further comprising one or more leak paths, the one or more leak paths allowing air to flow through the device even when air is restricted by the first and the second airflow resistors. 3. The device of claim 2, wherein the one or more leak paths comprise at least one aperture or channel through the first flap valve, the at least one aperture or channel being open even when the first flap valve is closed. 4. The device of claim 1, wherein the first holdfast is configured to form a seal between the respiratory device and the first nostril, and wherein the second holdfast is configured to form a seal between the respiratory device and the second nostril. 5. The device of claim 1, wherein the first and the second holdfast comprise a compliant material. 6. The device of claim 1, wherein the connector is a clip. 7. The device of claim 1, wherein the connector is one or more of: a clip, a tether, a strap, a band, a chain, and a string. 8. The device of claim 1, wherein the first rim and the second rim are oval. 9. The device of claim 1, wherein the first and second holdfast comprises silicone. 10. The device of claim 1, wherein the first and second rim comprises a compressible material. 11. The device of claim 1, wherein the first and second rim comprises a silicone rubber. 12. The device of claim 1, further comprising a filter within either the first or second passageway. 13. A whole-nose nasal respiratory device configured to engage both of a subject's nostrils, the device comprising: a first rim forming a first passageway, wherein the first rim is compressible;a first airflow resistor within the first passageway, the first airflow resistor comprising a first flap valve that inhibits exhalation through a first nostril more than inhalation through the first nostril;a second rim forming a second passageway, wherein the second rim is compressible;a second airflow resistor within the second passageway, the second airflow resistor comprising a second flap valve that inhibits exhalation through a second nostril more than inhalation through the second nostril;a connector comprising a clip connecting the first rim to the second rim. 14. The device of claim 13, further comprising one or more leak paths, the one or more leak paths allowing air to flow through the device even when air is restricted by the first and the second airflow resistors. 15. The device of claim 14, wherein the one or more leak paths comprise at least one aperture or channel through the first flap valve, the at least one aperture or channel being open even when the first flap valve is closed. 16. The device of claim 13, wherein the first and second rim are oval. 17. The device of claim 13, further comprising a therapeutic agent that is configured to come into contact with the subject's nostrils when the nasal respiratory device is worn. 18. The device of claim 13, wherein the first and second rim comprises a compressible material. 19. The device of claim 13, wherein the first and second rim comprises a silicone rubber. 20. A whole-nose nasal respiratory device configured to engage both of a subject's nostrils, the device comprising: a first rim forming a first passageway;a first airflow resistor within the first passageway, the first airflow resistor comprising a first flap valve that inhibits exhalation through a first nostril more than inhalation through the first nostril;a first holdfast on the first rim, the first holdfast configured to secure the first rim in communication with the first nostril when the device is worn;a second rim forming a second passageway;a second airflow resistor within the second passageway, the second airflow resistor comprising a second flap valve that inhibits exhalation through a second nostril more than inhalation through the second nostril;a second holdfast on the second rim, the second holdfast configured to secure the second rim in communication with the second nostril when the device is worn; anda connector connecting the first rim to the second rim.
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