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Human tissue kallikrein 1 glycosylation isoforms 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-038/48
  • A61P-003/10
  • C12N-009/96
  • C12N-009/64
출원번호 US-0153126 (2016-05-12)
등록번호 US-9839678 (2017-12-12)
발명자 / 주소
  • Charles, Matthew
  • Kolodka, Tadeusz
  • Williams, Mark
출원인 / 주소
  • DIAMEDICA INC.
인용정보 피인용 횟수 : 0  인용 특허 : 88

초록

Provided are preparations of tissue kallikrein-1 (KLK1) glycoforms having a defined number of oligosaccharide units per KLK1 molecule. Also provided are mixtures of such glycoforms, pharmaceutical compositions containing such glycoforms or mixtures thereof, methods of obtaining the rhKLK1 glycoforms

대표청구항

1. A method of treating an ischemic condition in a subject in need thereof, comprising administering to the subject a composition comprising a first mature human tissue kallikrein-1 (KLK1) polypeptide and a second mature human tissue kallikrein-1 (KLK1) polypeptide: wherein the first mature human KL

이 특허에 인용된 특허 (88)

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