최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
DataON 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Edison 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
---|---|
국제특허분류(IPC7판) |
|
출원번호 | US-0831396 (2013-03-14) |
등록번호 | US-9849142 (2017-12-26) |
발명자 / 주소 |
|
출원인 / 주소 |
|
대리인 / 주소 |
|
인용정보 | 피인용 횟수 : 7 인용 특허 : 600 |
Methods of treatment and dosage regimes using hydrophobic gel or foam compositions comprising a tetracycline antibiotic for accelerating the return of skin integrity and or in treating or alleviating a disorder including impetigo, acne, rosacea, a skin disease caused by a bacteria or a tetracycline
Methods of treatment and dosage regimes using hydrophobic gel or foam compositions comprising a tetracycline antibiotic for accelerating the return of skin integrity and or in treating or alleviating a disorder including impetigo, acne, rosacea, a skin disease caused by a bacteria or a tetracycline antibiotic responsive disease, wherein the foam composition or gel is administered topically to a target area on a subject having the disorder and wherein the target area comprises an area of skin, or mucosa or an eye.
1. A method of treating or alleviating impetigo comprising topically administering an effective amount of a tetracycline antibiotic foam to a target area on a mammal in need thereof, wherein the target area comprises an area of skin or mucosa, and wherein the tetracycline antibiotic foam is produced
1. A method of treating or alleviating impetigo comprising topically administering an effective amount of a tetracycline antibiotic foam to a target area on a mammal in need thereof, wherein the target area comprises an area of skin or mucosa, and wherein the tetracycline antibiotic foam is produced from a foamable composition comprising: (a) 60% to 90% by weight of at least one hydrophobic oil;(b) a wax selected from the group consisting of a beeswax, a hydrogenated castor oil, a paraffin wax, a plant wax, an animal wax, a polyethylene wax, and a mixture of two or more thereof;(c) at least one solid fatty alcohol having a carbon chain length of 14 to 22 carbons;(d) optionally at least one solid fatty acid having a carbon chain length of 12 to 28 carbons;(e) a tetracycline antibiotic selected from the group consisting of tetracycline, oxytetracycline, demeclocycline, doxycycline, lymecycline, meclocycline, methacycline, minocycline, rolitetracycline, chlorotetracycline, tigecycline, and a mixture of two or more thereof; and(f) a liquefied or compressed gas propellant; and wherein the foamable composition does not comprise a surfactant. 2. The method of claim 1, wherein the concentration of the liquefied or compressed gas propellant is 3% to 25% by weight of the foamable composition. 3. The method of claim 1, wherein the wax is selected from the group consisting of a beeswax, a hydrogenated castor oil, and a mixture thereof. 4. The method of claim 1, wherein the tetracycline antibiotic is present in a free base form, a salt form, a hydrate form, or a complex form. 5. The method of claim 4, wherein the tetracycline antibiotic is minocycline hydrochloride, and wherein the concentration of minocycline hydrochloride is 0.2% to 10% by weight of the foamable composition. 6. The method of claim 4, wherein the tetracycline antibiotic is doxycycline hyclate, and wherein the concentration of doxycycline hyclate is 0.2% to 10% by weight of the foamable composition. 7. The method of claim 1, wherein the tetracycline antibiotic foam is administered twice daily. 8. The method of claim 1, wherein the hydrophobic oil is selected from the group consisting of a mineral oil, a soybean oil, a coconut oil, cyclomethicone, and a mixture of two or more thereof. 9. The method of claim 1, wherein the at least one solid fatty alcohol is selected from the group consisting of myristyl alcohol, cetostearyl alcohol, stearyl alcohol, behenyl alcohol, and a mixture of two or more thereof. 10. The method of claim 1, wherein the foamable composition does comprise the optional at least one solid fatty acid having a carbon chain length of 12 to 28 carbons. 11. The method of claim 10, wherein the least one solid fatty acid having a carbon chain length of 12 to 28 carbons is stearic acid. 12. The method of claim 1, wherein the foamable composition further comprises fumed silica. 13. The method of claim 1, wherein the mammal is a human. 14. The method of claim 1, wherein tetracycline antibiotic foam is administered at least once daily. 15. The method of claim 1, wherein the tetracycline antibiotic is micronized. 16. The method of claim 1, wherein the concentration of tetracycline antibiotic is 0.2 to 10% by weight of the foamable composition.
Copyright KISTI. All Rights Reserved.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.