[특허]Methods and products for tissue repair

Methods and products for tissue repair 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	A61K-008/65 A61L-027/24 A61K-038/39 A61K-045/06 A61L-027/54 A61L-027/56 A61L-027/58 A61K-031/401 A61K-035/17 A61K-035/19 A61L-027/36 A61L-027/50
출원번호	US-0082235 (2016-03-28)
등록번호	US-9849213 (2017-12-26)
발명자 / 주소	Murray, Martha M.
출원인 / 주소	Children's Medical Center Corporation
대리인 / 주소	Wolf, Greenfield & Sacks, P.C.
인용정보	피인용 횟수 : 0 인용 특허 : 80

초록

Methods and devices for the repair of articular tissue using collagen material are provided. Compositions of collagen material and related kits are also provided.

대표청구항 ▼

1. A composition comprising a sterile solution of solubilized collagen in a concentration of greater than 5 and less than or equal to 50 mg/ml and having a viscosity of 1,000-200,000 centipoise, a buffer wherein the composition has an osmolarity of 280-350 mOs/kg, wherein the composition is free of crosslinking agent. 2. The composition of claim 1, wherein the solution is a liquid or gel. 3. The composition of claim 1, wherein the solubilized collagen is present in a concentration of greater than 15 mg/ml and less than or equal to 40 mg/ml. 4. The composition of claim 1, further comprising a platelet, white blood cells, an antibiotic, an anti-plasmin agent, insoluble collagen, a plasminogen activator inhibitor, a glycosaminoglycan, decorin or biglycan. 5. The composition of claim 1, wherein the composition has a pH of 6.8-8.0. 6. The composition of claim 1, wherein the collagen is enzyme solubilized collagen or atelocollagen. 7. The composition of claim 1, wherein the solution is maintained at a temperature of 4° C. 8. A quick set composition comprising a sterile solution of solubilized collagen in a concentration of greater than 5 and less than or equal to 50 mg/ml and having a viscosity of 1,000-200,000 centipoises and a pH of 6.8-8.0, wherein the solution has an osmolarity of 280-350 mOs/kg, wherein the solution sets into a scaffold within 10 minutes of exposure to temperatures of greater than 30° C. 9. A compressible expandable scaffold, comprising a collagen sponge, wherein the collagen is type I soluble collagen and collagen is in a concentration of grater than 5 and less than or equal to 50 mg/ml, wherein the collagen sponge is free of crosslinking agent.

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IPC	Description
A	생활필수품
A62	인명구조; 소방(사다리 E06C)
A62B	인명구조용의 기구, 장치 또는 방법(특히 의료용에 사용되는 밸브 A61M 39/00; 특히 물에서 쓰이는 인명구조 장치 또는 방법 B63C 9/00; 잠수장비 B63C 11/00; 특히 항공기에 쓰는 것, 예. 낙하산, 투출좌석 B64D; 특히 광산에서 쓰이는 구조장치 E21F 11/00)
A62B-1/08	.. 윈치 또는 풀리에 제동기구가 있는 것

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연합인증

Methods and products for tissue repair 원문보기

초록

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Methods and products for tissue repair 원문보기

초록

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연구과제 타임라인

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