A medical implant system is described for inhibiting infection associated with a joint prosthesis implant. An inventive system includes an implant body made of a biocompatible material which has a metal component disposed on an external surface of the implant body. A current is allowed to flow to th
A medical implant system is described for inhibiting infection associated with a joint prosthesis implant. An inventive system includes an implant body made of a biocompatible material which has a metal component disposed on an external surface of the implant body. A current is allowed to flow to the metal component, stimulating release of metal ions toxic to microbes, such as bacteria, protozoa, fungi, and viruses. One detailed system is completely surgically implantable in the patient such that no part of the system is external to the patient while the system is in use. In addition, externally controlled devices are provided which allow for modulation of implanted components.
대표청구항▼
1. A medical device, comprising: a body having an external surface;an antimicrobial material disposed on the external surface of the body; anda current generator connected to the body such that a flow of antimicrobial ions is created from the antimicrobial material into a conductive medium adjacent
1. A medical device, comprising: a body having an external surface;an antimicrobial material disposed on the external surface of the body; anda current generator connected to the body such that a flow of antimicrobial ions is created from the antimicrobial material into a conductive medium adjacent the external surface of the body. 2. The medical device of claim 1, wherein said current generator comprises: a power source including a first element and a second element, wherein at least one of the first element and the second element is in electrical communication with the antimicrobial material such that the ion flow is created when a current path is established that includes the power source and at least a part of the antimicrobial material. 3. The medical device of claim 2, further comprising: an insulator that allows the current path to be established by forcing the ion flow into the conductive medium adjacent the implant body. 4. The medical device of claim 3, wherein the insulator is configured to prevent current flowing from the first element from reaching the second element without completing a circuit including the conductive medium adjacent to the external surface of the body. 5. The medical device of claim 3, wherein the antimicrobial material is disposed on a portion of the external surface of the implant body ranging from 1-100% of the external surface of the implant body, excluding any portion of the external surface occupied by the insulator. 6. The medical device of claim 3, wherein the antimicrobial material is disposed on a portion of the external surface of the body ranging from 50-99% of the external surface of the body, excluding any portion of the external surface occupied by the insulator. 7. The medical device of claim 3, wherein the antimicrobial material is disposed as at least two regions of coating on the external surface of the body, at least one region of coating in electrical communication with the first terminal and at least one region of coating in electrical communication with the second terminal, wherein the insulator is placed in the current path between the first terminal of the power source and the second terminal of the power source, andwherein the insulator electrically insulates the at least two regions of coating from each other. 8. The medical device of claim 1 wherein the antimicrobial material is a metal. 9. The medical device of claim 1 wherein the antimicrobial material is a metal-doped material. 10. The medical device of claim 1 wherein the body is tubular in shape. 11. The medical device of claim 1, wherein the body includes: an internal cavity having a wall and an opening; anda cap removably disposed in the opening of the internal cavity, wherein the power source is disposed in the internal cavity. 12. The medical device of claim 11, further comprising a metal component disposed on a portion of the internal cavity wall. 13. The medical device of claim 1, wherein the antimicrobial material is selected from the group consisting of: silver; copper; both silver and copper; both silver and cadmium; both copper and cadmium; and a combination of silver, copper and cadmium. 14. The medical device of claim 1, wherein the antimicrobial material is selected from the group consisting of: gold, zinc, cobalt, nickel, platinum, palladium, manganese, chromium; and a combination thereof. 15. The medical device of claim 1, wherein the antimicrobial material ranges in thickness between 1×10−9-5×10−3 meters. 16. The medical device of claim 1, wherein the medical device is configured to be temporarily or permanently implanted within a patient. 17. The medical device of claim 1, wherein the conductive medium comprises conductive body tissue or fluid.
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