Devices for vestibular or cranial nerve stimulation
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61F-007/00
A61F-007/12
A61F-007/02
A61N-001/32
출원번호
US-0251860
(2014-04-14)
등록번호
US-9861518
(2018-01-09)
발명자
/ 주소
Rogers, Lesco L.
출원인 / 주소
Scion Neurostim, LLC
대리인 / 주소
Myers Bigel, P.A.
인용정보
피인용 횟수 :
0인용 특허 :
45
초록▼
A nerve tissue stimulator configured for contacting to or insertion in the body of a subject to stimulate a tissue therein, said probe comprising: (a) a support configured for contacting to or positioning adjacent a tissue of said subject; (b) at least one thermoelectric device (TED) on said support
A nerve tissue stimulator configured for contacting to or insertion in the body of a subject to stimulate a tissue therein, said probe comprising: (a) a support configured for contacting to or positioning adjacent a tissue of said subject; (b) at least one thermoelectric device (TED) on said support and positioned for thermally stimulating said nerve tissue.
대표청구항▼
1. A device comprising: an ear insert sized and configured so as to be at least partially insertable into a subject's ear canal;a thermoelectric device (TED) attached to said ear insert;a heat sink; anda controller,wherein said TED is thermally coupled between said ear insert and said heat sink, and
1. A device comprising: an ear insert sized and configured so as to be at least partially insertable into a subject's ear canal;a thermoelectric device (TED) attached to said ear insert;a heat sink; anda controller,wherein said TED is thermally coupled between said ear insert and said heat sink, andwherein said controller is operatively connected to said TED and is configured to activate said TED so as to produce a thermal stimulus. 2. The device of claim 1, wherein said TED comprises a thin film thermoelectric transducer. 3. The device of claim 1, wherein said heat sink is configured on said device for positioning outside the ear canal of said subject. 4. The device of claim 1, wherein said controller is configured to control the magnitude, duration and/or waveform of said thermal stimulus by modulating activation of said TED. 5. The device of claim 1, further comprising a sensor that is operatively connected to said controller, wherein said controller is configured to control activation of said TED responsive to feedback received from said sensor. 6. The device of claim 1, wherein said controller is configured to cyclically activate said TED. 7. The device of claim 1, wherein said controller is configured to activate said TED so as to produce the thermal stimulus comprising a uniform waveform. 8. The device of claim 1, wherein said controller is configured to activate said TED so as to produce the thermal stimulus comprising a stochastic waveform. 9. The device of claim 1, wherein said controller is configured to activate said TED so as to produce the thermal stimulus comprising a randomized waveform. 10. The device of claim 1, wherein said controller is configured to activate said TED so as to produce the thermal stimulus comprising one or more thermal pulses. 11. The device of claim 1, wherein said controller is configured to activate said TED so as to produce the thermal stimulus comprising a cooling thermal stimulus. 12. The device of claim 1, wherein said controller is configured to activate said TED so as to produce the thermal stimulus comprising a warming thermal stimulus. 13. The device of claim 1, further comprising an electrode attached to said ear insert and operatively connected to said controller, wherein said controller is configured to activate said electrode so as to produce an electrical stimulus. 14. The device of claim 13, wherein said controller is configured to control the magnitude, duration and/or waveform of said electrical stimulus by modulating activation of said electrode. 15. The device of claim 13, further comprising a sensor that is operatively connected to said controller, wherein said controller is configured to control activation of said TED and/or activation of said electrode responsive to feedback received from said sensor. 16. The device of claim 13, wherein said controller is configured to separately and selectively activate said TED and said electrode. 17. A device comprising: an ear insert sized and configured so as to be at least partially insertable into a subject's ear canal;a thermoelectric device (TED) attached to said ear insert;an electrode attached to said ear insert;a heat sink; anda controller,wherein said TED is thermally coupled between said ear insert and said heat sink,wherein said heat sink is configured on said device for positioning outside the ear canal of said subject,wherein said controller is operatively connected to said TED and is configured to activate said TED so as to produce a thermal stimulus, andwherein said controller is configured to activate said electrode so as to produce an electrical stimulus. 18. The device of claim 17, wherein said controller is configured to control the magnitude, duration and/or waveform of said thermal stimulus by modulating activation of said TED and to control the magnitude, duration and/or waveform of said electrical stimulus by modulating activation of said electrode. 19. The device of claim 17, further comprising a sensor that is operatively connected to said controller, wherein said controller is configured to control activation of said TED and/or activation of said electrode responsive to feedback received from said sensor. 20. The device of claim 17, wherein said controller is configured to separately and selectively activate said TED and said electrode. 21. A method, comprising: providing a device comprising:an ear insert sized and configured so as to be at least partially insertable into a subject's car canal;a thermoelectric device (TED) attached to said ear insert;a heat sink; anda controller,wherein said TED is thermally coupled between said ear insert and said heat sink, andwherein said controller is operatively connected to said TED and is configured to activate said TED so as to produce a thermal stimulus;inserting at least a portion of said ear insert into the ear canal of a subject;activating said TED. 22. The method of claim 21, wherein activating said TED comprises: cooling the ear canal of said subject by at least about 0.5 to about 37 degrees Centigrade;warming the ear canal of said subject by at least about 0.5 to about 6.5 degrees Centigrade;delivering one or more thermal pulses to the ear canal of said subject;delivering one or more thermal waveforms to the ear canal of said subject;cyclically activating said TED; and/orcyclically altering the temperature profile of the ear canal of said subject. 23. A method, comprising: providing a device comprising: an ear insert sized and configured so as to be at least partially insertable into a subject's ear canal;a thermoelectric device (TED) attached to said ear insert;an electrode attached to said ear insert;a heat sink; anda controller,wherein said TED is thermally coupled between said ear insert and said heat sink,wherein said heat sink is configured on said device for positioning outside the ear canal of said subject,wherein said controller is operatively connected to said TED and is configured to activate said TED so as to produce a thermal stimulus, andwherein said controller is configured to activate said electrode so as to produce an electrical stimulus;inserting at least a portion of said ear insert into the ear canal of a subject;activating said TED and/or said electrode. 24. The method of claim 23, wherein activating said TED comprises: cooling the ear canal of said subject by at least about 0.5 to about 37 degrees Centigrade;warming the ear canal of said subject by at least about 0.5 to about 6.5 degrees Centigrade;delivering one or more thermal pulses to the ear canal of said subject;delivering one or more thermal waveforms to the ear canal of said subject;cyclically activating said TED; and/orcyclically altering the temperature profile of the ear canal of said subject. 25. The method of claim 23, wherein activating said TED and/or said electrode comprises sequentially activating said TED and said electrode. 26. The method of claim 23, wherein activating said TED and/or said electrode comprises simultaneously activating said TED and said electrode.
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