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An ophthalmic system may comprise an imaging device having a field of view oriented toward the eye of the patient; a patient interface housing defining a passage therethrough, having a distal end coupled to one or more seals configured to be directly engaged with one or more surfaces of the eye of t

An ophthalmic system may comprise an imaging device having a field of view oriented toward the eye of the patient; a patient interface housing defining a passage therethrough, having a distal end coupled to one or more seals configured to be directly engaged with one or more surfaces of the eye of the patient, and wherein the proximal end is configured to be coupled to the patient workstation such that at least a portion of the field of view of the imaging device passes through the passage; and two or more registration fiducials coupled to the patient interface housing in a predetermined geometric configuration relative to the patient interface housing within the field of view of the imaging device such that they may be imaged by the imaging device in reference to predetermined geometric markers on the eye of the patient which may also be imaged by the imaging device.

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1. A method for ophthalmic intervention on an eye of a patient, comprising: a) orienting a field of view of an imaging device toward the eye of the patient;b) coupling a distal end of a patient interface housing to one or more surfaces of the eye of the patient, and coupling a proximal end of the pa

1. A method for ophthalmic intervention on an eye of a patient, comprising: a) orienting a field of view of an imaging device toward the eye of the patient;b) coupling a distal end of a patient interface housing to one or more surfaces of the eye of the patient, and coupling a proximal end of the patient interface housing to a patient workstation such that at least a portion of the field of view of the imaging device passes through a passage of the patient interface housing defined by the proximal and distal ends;c) successively imaging, within the field of the view of the imaging device, one or more registration fiducials in reference to predetermined geometric markers on the eye of the patient, which are also imaged by the imaging device, the one or more registration fiducials being coupled to the patient interface housing in a predetermined geometric configuration relative to the patient interface housing; andd) processing successive imaging data generated via the imaging device so as to determine a successive position in X, Y, and Z, together with a successive pitch, yaw, and roll of the patient interface housing. 2. The method of claim 1, wherein a laser system is operatively coupled to the imaging device. 3. The method of claim 2, further comprising producing a treatment beam with the laser system that may be directed through the passage of the patient interface housing and into the eye of the patient. 4. The method of claim 3, wherein the treatment beam is suitable for creating dielectric breakdown within a cataractous crystalline lens of the eye. 5. The method of claim 4, wherein the treatment beam is a pulsed treatment beam with a pulse repetition rate between about 1 kHz and about 200 kHz. 6. The method of claim 4, wherein the treatment beam has a wavelength between about 800 nm and about 1,100 nm. 7. The method of claim 4, wherein the treatment beam is a pulsed treatment beam having a pulse energy between about 1 microjoule and about 1,000 microjoules. 8. The method of claim 4, wherein the treatment beam is a pulsed treatment beam with a pulse duration between about 100 femtoseconds and about 10 picoseconds. 9. The method of claim 1, wherein the patient interface housing comprises an optical lens coupled to the housing having a focal axis aligned to pass through the passage of the housing. 10. The method of claim 1, further comprising directing illumination radiation from a position adjacent the imaging device toward the eye of the patient. 11. The method of claim 1, wherein at least a portion of the illumination radiation is directed through the passage of the patient interface housing. 12. The method of claim 1, wherein at least a portion of the patient interface housing is translucent to the illumination radiation, and at least a portion of the illumination radiation is directed across the translucent portion of the patient interface housing toward the eye of the patient. 13. The method of claim 10, wherein the illumination radiation is infrared radiation. 14. The method of claim 10, wherein the illumination radiation is visible light radiation. 15. The method of claim 1, wherein the imaging device comprises an optical coherence tomography system configured to measure the coherence of radiation scattered into an interferometer from the field of view. 16. The method of claim 13, wherein the fiducials comprise one or more materials that fluoresce in infrared radiation. 17. The method of claim 13, wherein the fiducials comprise one or more materials that highly contrast in infrared radiation relative to other surrounding materials. 18. The method of claim 13, wherein the fiducials comprise one or more surface irregularities relative to other surrounding surfaces. 19. The method of claim 18, wherein the one or more surface irregularities are selected from the group consisting of: a concave feature, a convex feature, a depressed edge, a depressed step, a projecting edge, a projecting step, and an intersection of lines. 20. The method of claim 14, wherein the fiducials comprise one or more materials that highly contrast in visible light radiation relative to other surrounding materials. 21. The method of claim 14, wherein the fiducials comprise one or more surface irregularities relative to other surrounding surfaces. 22. The method of claim 21, wherein the one or more surface irregularities are selected from the group consisting of: a concave feature, a convex feature, a depressed edge, a depressed step, a projecting edge, a projecting step, and an intersection of lines. 23. The method of claim 15, wherein the fiducials comprise one or more surface irregularities relative to other surrounding surfaces. 24. The method of claim 23, wherein the one or more surface irregularities are selected from the group consisting of: a concave feature, a convex feature, a depressed edge, a depressed step, a projecting edge, a projecting step, and an intersection of lines. 25. The method of claim 1, wherein the three or more fiducials are positioned upon an inner annulus formed by the distal end of the patient interface housing. 26. The method of claim 25, wherein the first and second fiducials are positioned at opposite sides of the inner annulus. 27. The method of claim 25, wherein the three or more fiducials comprise three fiducials distributed nonhomogeneously about the inner annulus.