Microchip substance delivery devices having low-power electromechanical release mechanisms
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61K-009/00
A61M-031/00
A61M-005/142
A61M-005/44
A61N-001/04
출원번호
US-0483278
(2014-09-11)
등록번호
US-9937124
(2018-04-10)
발명자
/ 주소
Chey, S. Jay
Dang, Bing
Knickerbocker, John U.
Latzko, Kenneth F.
Branquinho Teresa Maria, Joana Sofia
Turlapati, Lavanya
Webb, Bucknell C.
Wright, Steven L.
출원인 / 주소
International Business Machines Corporation
대리인 / 주소
Percello, Louis J.
인용정보
피인용 횟수 :
0인용 특허 :
17
초록▼
Electromechanical substance delivery devices are provided which implement low-power electromechanical release mechanisms for controlled delivery of substances such as drugs and medication. For example, an electromechanical device includes a substrate having a cavity formed in a surface of the substr
Electromechanical substance delivery devices are provided which implement low-power electromechanical release mechanisms for controlled delivery of substances such as drugs and medication. For example, an electromechanical device includes a substrate having a cavity formed in a surface of the substrate, a membrane disposed on the surface of the substrate covering an opening of the cavity, and a seal disposed between the membrane and the surface of the substrate. The seal surrounds the opening of the cavity, and the seal and membrane are configured to enclose the cavity and retain a substance within the cavity. An electrode structure is configured to locally heat a portion of the membrane in response to a control voltage applied to the electrode structure, and create a stress that causes a rupture in the locally heated portion of the membrane to release the substance from within the cavity.
대표청구항▼
1. An electromechanical device, comprising: a substrate comprising a cavity formed in a surface of the substrate;a membrane disposed on the surface of the substrate covering an opening of the cavity;a seal disposed between the membrane and the surface of the substrate, wherein the seal surrounds the
1. An electromechanical device, comprising: a substrate comprising a cavity formed in a surface of the substrate;a membrane disposed on the surface of the substrate covering an opening of the cavity;a seal disposed between the membrane and the surface of the substrate, wherein the seal surrounds the opening of the cavity, and wherein the seal and membrane are configured to enclose the cavity and retain a substance within the cavity; andan electrode structure configured to locally heat a portion of the membrane in response to a control voltage applied to the electrode structure, and create a stress that causes a rupture in the locally heated portion of the membrane to release the substance from within the cavity:wherein the membrane comprises a plurality of voids formed within the membrane, wherein the plurality of voids are configured to reduce a strength of the locally heated portion of the membrane and facilitate rupturing of the locally heated portion of the membrane. 2. The device of claim 1, wherein the substance comprises medication. 3. The device of claim 1, wherein the locally heated portion of the membrane has a lateral dimension that is less than about two times a thickness of the membrane. 4. The device of claim 1, wherein a portion of the electrode structure comprises a V-shaped electrode, wherein an apex portion of the V-shaped electrode has a width that is less than a width of a remaining portion of the V-shaped electrode, and wherein the apex portion is configured to provide said localized heating of the portion of the membrane. 5. The device of claim 4, wherein the V-shaped electrode is formed with an angle of about 108 degrees to about 120 degrees. 6. The device of claim 1, wherein the membrane is formed in a tensile-stressed state, such that a portion of the membrane is configured to peel back away from a ruptured portion of the membrane. 7. The device of claim 1, further comprising a stress layer disposed on the membrane, wherein the stress layer is configured to apply a tensile stress to the membrane and cause a portion of the membrane to peel back away from a ruptured portion of the membrane. 8. The device of claim 1, wherein the membrane is formed of an insulating material. 9. The device of claim 1, wherein the locally heated portion of the membrane comprises a metallic material that is configured to melt due to said localized heating thereof. 10. An electromechanical device, comprising: a substrate comprising a cavity formed in a surface of the substrate;a seal disposed on the surface of the substrate surrounding an opening of the cavity;a membrane disposed on the surface of the substrate covering the opening of the cavity, wherein the seal and membrane are configured to enclose the cavity and retain a substance within the cavity;an electrode structure comprising a first contact, a second contact, and a plurality of filaments arranged adjacent to each other, wherein the plurality of filaments are electrically connected in parallel to the first contact and the second contact of the electrode structure, wherein the filaments are configured to melt in succession in response to a control voltage applied to the first contact and the second contact, and cause a rupture in a portion of the membrane adjacent to the plurality of filaments to release the substance from within the cavity;wherein the plurality of filaments comprises parallel filaments disposed between the first contact and the second contact, wherein each filament includes a fuse portion that is configured to melt, wherein a centrally disposed one of the filaments has a width that is greater than widths of the other filament structures, and wherein the widths of the other filaments disposed on each side of the centrally disposed filament are made successively smaller;wherein the fuse portions of the filaments are arranged along a V-shaped line, wherein a fuse portion of the centrally disposed filament is aligned to an apex of the V-shaped line; andwherein the membrane comprises a plurality of voids formed within the membrane along the V-shaped line, wherein the plurality of voids is configured to reduce a strength of the membrane and facilitate rupturing a portion of the membrane adjacent to the fuse portions of the filaments. 11. The An electromechanical device, comprising: a substrate comprising a cavity formed in a surface of the substrate;a seal disposed on the surface of the substrate surrounding an opening of the cavity;a membrane disposed on the surface of the substrate covering the opening of the cavity, wherein the seal and membrane are configured to enclose the cavity and retain a substance within the cavity;an electrode structure comprising a first contact, a second contact, and a plurality of filaments arranged adjacent to each other, wherein the plurality of filaments are electrically connected in parallel to the first and second contacts of the electrode structure, wherein the filaments are configured to melt in succession in response to a control voltage applied to the first and second contacts, and cause a rupture in a portion of the membrane adjacent to the plurality of filaments to release the substance from within the cavity;wherein the plurality of filaments comprises circular filament structures that are concentrically arranged and connected to the first and second contacts. 12. The device of claim 11, wherein the membrane comprises a plurality of voids formed within the membrane along one or more radial lines that radially extend from a center point within an innermost circular filament. 13. An electromechanical device, comprising: a substrate comprising a cavity formed in a surface of the substrate;a membrane disposed on the surface of the substrate covering an opening of the cavity, wherein the membrane comprises a plurality of voids formed within the membrane, wherein the plurality of voids are configured to reduce a strength of a portion of the membrane within which the voids are formed;a seal disposed between the membrane and the surface of the substrate, wherein the seal surrounds the opening of the cavity, wherein the seal and membrane are configured to enclose the cavity and retain a substance within the cavity; andan electrode structure configured to thermally expand in response to a control voltage applied to the electrode structure and apply a tensile stress to the portion of the membrane within which the voids are formed and cause a rupture in said portion of the membrane to release the substance from within the cavity. 14. The device of claim 13, wherein a portion of the electrode structure comprises a V-shaped electrode, and wherein the plurality of voids are formed within the membrane along a V-shaped line adjacent to an inner edge of the V-shaped electrode. 15. The device of claim 13, wherein a portion of the electrode structure comprises a semi-circular electrode, and wherein the plurality of voids are formed within the membrane along a semi-circular line adjacent to an inner edge of the semi-circular electrode. 16. The device of claim 13, wherein the membrane is formed in a tensile-stressed state, such that a portion of the membrane is configured to peel back away from a ruptured portion of the membrane. 17. The device of claim 13, wherein the membrane comprises an expansion groove to enable stretching of the membrane due to thermal expansion of the electrode structure. 18. An electromechanical device, comprising: a substrate comprising a cavity formed in a surface of the substrate;a membrane disposed on the surface of the substrate covering an opening of the cavity;a seal disposed between the membrane and the surface of the substrate, wherein the seal surrounds the opening of the cavity, and wherein the seal and membrane are configured to enclose the cavity and retain a substance within the cavity; andan electrode structure formed on the membrane, wherein the electrode structure is formed in a tensile-stressed state, and comprises a fuse portion,wherein the membrane comprises a plurality of voids formed within the membrane along one or more edges of the electrode structure, wherein the plurality of voids are configured to reduce a strength of a portion of the membrane along the one or more edges of the electrode structure, andwherein the fuse portion of the electrode structure is configured to melt in response to a control voltage applied to the electrode structure and cause the electrode structure to peel back and rupture the portion of the membrane in which the plurality of voids are formed along the one or more edges of the electrode structure. 19. The device of claim 18, wherein the electrode structure comprises a first and a second triangular-shaped electrode having a first apex and a second apex, respectively, wherein the fuse portion is connected between the first apex and the second apex. 20. The device of claim 19, wherein the plurality of voids formed within the membrane comprises: a first set of voids that extend along a first V-shaped line adjacent to first edges of the first and second triangular-shaped electrodes; anda second set of voids that extend along a second V-shaped line adjacent to second edges of the first and second triangular-shaped electrodes.
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