Differential neurostimulation therapy driven by physiological therapy
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61N-001/00
A61N-001/36
A61M-005/142
A61N-001/05
A61B-005/00
A61B-005/04
A61B-005/0476
A61B-005/07
A61B-005/021
A61B-005/026
A61B-005/0488
A61B-005/145
출원번호
US-0246351
(2016-08-24)
등록번호
US-9943690
(2018-04-17)
발명자
/ 주소
Pless, Benjamin D.
Tcheng, Thomas K.
출원인 / 주소
NeuroPace, Inc.
대리인 / 주소
Loza & Loza, LLP
인용정보
피인용 횟수 :
0인용 특허 :
103
초록▼
An implantable neurostimulator system adapted to provide therapy for various neurological disorders is capable of varying therapy delivery strategies based on the context, physiological or otherwise, into which the therapy is to be delivered. Responsive and scheduled therapies can be varied dependin
An implantable neurostimulator system adapted to provide therapy for various neurological disorders is capable of varying therapy delivery strategies based on the context, physiological or otherwise, into which the therapy is to be delivered. Responsive and scheduled therapies can be varied depending on various sensor measurements, calculations, inferences, and device states (including elapsed times and times of day) to deliver an appropriate course of therapy under the circumstances.
대표청구항▼
1. An external apparatus comprising: a memory;a software operating program stored in the memory and configured to process an EEG signal received from a device remote from the external apparatus, the EEG signal corresponding to a sensor signal activity characterizable by one or more events that are r
1. An external apparatus comprising: a memory;a software operating program stored in the memory and configured to process an EEG signal received from a device remote from the external apparatus, the EEG signal corresponding to a sensor signal activity characterizable by one or more events that are representative of a particular patient's neurological disorder or condition, wherein each event is defined in the remote device by at least one set of detection parameters; anda communication component configured to establish a communication link with the remote device to enable the external apparatus to receive the EEG signal from the remote device,wherein the software operating program is configured to process the EEG signal to simulate which set of detection parameters would result in detecting which event in the EEG signal, and to predict whether an existing set of detection parameters of the remote device should be modified to correspond to a set of detection parameters to increase the likelihood that one or more events will be detected by the remote device. 2. The apparatus of claim 1, wherein the device remote from the external apparatus is at least partially implanted in the patient. 3. The apparatus of claim 1, wherein the device remote from the external apparatus is an implanted neurostimulator. 4. The apparatus of claim 1, wherein the one or more events include a form of epileptiform activity, such as a form of epileptiform activity associated with an epileptic seizure and a form of epileptiform activity associated with a precursor to an epileptic seizure. 5. The apparatus of claim 1, wherein the set of detection parameters include parameters that define an instance of a half wave analysis tool, parameters that define an instance of a line length analysis tool, parameters that define an instance of an area analysis tool, and parameters that define an instance of a half wave tool in combination with either a line length analysis tool or an area analysis tool. 6. The external apparatus of claim 1, further comprising a clinician input device in operable communication with the software operating program stored in the memory, and adapted to receive clinician inputs defining one or more of the sets of detection parameters. 7. The external apparatus of claim 1, further comprising a clinician input device in operable communication with the software operating program stored in the memory, and adapted to receive clinician inputs initiating a programming of one or more of the sets of detection parameters into an implantable medical device, wherein the communication component is configured to establish a communication link with the implantable medical device, and the software operating program is configured to download the one or more of the sets of detection parameters into the implantable medical device over the communication link. 8. A method comprising: establishing a communication link with a remote device;receiving, at an external apparatus, an EEG signal from the remote device, the EEG signal corresponding to a sensor signal activity characterizable by one or more events that are representative of a particular patient's neurological disorder or condition, wherein each event is defined in the remote device by at least one set of detection parameters; andprocessing, at the external apparatus, the received EEG signal to simulate which set of detection parameters would result in detecting which event in the EEG signal, and to predict whether an existing set of detection parameters of the remote device should be modified to correspond to a set of detection parameters to increase the likelihood that one or more events will be detected by the remote device. 9. The method of claim 8, wherein the device remote from the external apparatus is at least partially implanted in the patient. 10. The method of claim 8, wherein the device remote from the external apparatus is an implanted neurostimulator. 11. The method of claim 8, wherein the one or more events include a form of epileptiform activity, such as a form of epileptiform activity associated with an epileptic seizure and a form of epileptiform activity associated with a precursor to an epileptic seizure. 12. The method of claim 8, wherein the set of detection parameters include parameters that define an instance of a half wave analysis tool, parameters that define an instance of a line length analysis tool, parameters that define an instance of an area analysis tool, and parameters that define an instance of a half wave tool in combination with either a line length analysis tool or an area analysis tool. 13. The method of claim 8, further comprising receiving, at the external apparatus, clinician inputs defining one or more of the sets of detection parameters. 14. The method of claim 8, further comprising: receiving, at the external apparatus, clinician inputs initiating a programming of one or more of the sets of detection parameters into an implantable medical device,establish a communication link with the implantable medical device, anddownload the one or more of the sets of detection parameters into the implantable medical device over the communication link. 15. A medical device system, comprising: an implantable medical device including: a sensing subsystem configured to sense an EEG signal sensed from a patient, the EEG signal corresponding to a sensor signal activity characterizable by one or more events that are representative of a particular patient's neurological disorder or condition, wherein each event is defined in the implantable medical device by at least one set of detection parameters;a memory configured to store data corresponding to the EEG signal; anda communication component configured to establish a communication link with an external apparatus; andan external apparatus including: a memory;a communication component configured to establish the communication link with the implantable medical device to enable the external apparatus to receive the EEG signal from the implantable medical device; anda software operating program stored in the memory and configured to process the EEG signal to simulate which set of detection parameters would result in detecting which event in the EEG signal, and to predict whether an existing set of detection parameters of the implantable medical device should be modified to correspond to a set of detection parameters to increase the likelihood that one or more events will be detected by the implantable medical device.
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