[특허]Microfluidic system including a bubble valve for regulating fluid flow through a microchannel

Microfluidic system including a bubble valve for regulating fluid flow through a microchannel 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	B01L-003/00 F16K-099/00
출원번호	US-0689508 (2015-04-17)
등록번호	US-9943847 (2018-04-17)
발명자 / 주소	Gilbert, John R. Böhm, Sebastian Deshpande, Manish
출원인 / 주소	CYTONOME/ST, LLC
대리인 / 주소	McCarter & English, LLP
인용정보	피인용 횟수 : 0 인용 특허 : 127

초록 ▼

A microfluidic system includes a bubble valve for regulating fluid flow through a microchannel. The bubble valve includes a fluid meniscus interfacing the microchannel interior and an actuator for deflecting the membrane into the microchannel interior to regulate fluid flow. The actuator generates a

대표청구항 ▼

1. A microfluidic device, comprising: a microchannel having an interior bounded by a side wall, an inlet, a switching region, and a plurality of outlet channels downstream of the switching region, the microchannel formed in a microfluidic chip substrate and configured to accommodate a flow of liquid through the microchannel;a valve located in the switching region comprising a sealed reservoir, a side passage extending between the reservoir and the interior of the microchannel via an aperture in the side wall, the side passage configured to accommodate a volume of liquid between the interior of the microchannel and the reservoir; andan actuator integrated in the microfluidic chip, the actuator configured to increase an internal pressure of the reservoir and move at least a portion of the volume of the liquid from the side passage into the microchannel to deflect a portion of the liquid flowing through the microchannel. 2. The microfluidic device of claim 1, wherein the actuator is configured to vary the volume of the reservoir. 3. The microfluidic device of claim 1, wherein actuation of the valve does not block the flow of liquid through the microchannel. 4. The microfluidic device of claim 1, wherein the actuator comprises one of a piezoelectric actuator and an electromagnetic actuator. 5. The microfluidic device of claim 1, wherein the sealed reservoir includes a movable wall, and wherein the actuator deflects the movable wall to increase the internal pressure of the sealed reservoir. 6. The microfluidic device of claim 1, wherein the sealed reservoir includes a flexible membrane, and wherein the actuator flexes the flexible membrane to increase the internal pressure of the sealed reservoir. 7. The microfluidic device of claim 1, wherein a stream of particles in a carrier fluid flows through the microchannel, and wherein, when the actuator increases the internal pressure of the reservoir, a pressure pulse selectively deflects a particle having a predetermined characteristic from the stream of particles. 8. The microfluidic device of claim 1, wherein increasing the internal pressure of the reservoir generates a pressure pulse within the switching region, andwherein the pressure pulse travels across the flow direction of the liquid flowing through the microchannel. 9. The microfluidic device of claim 8, further comprising a second sealed reservoir for absorbing the pressure pulse.

이 특허에 인용된 특허 (127)

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IPC	Description
A	생활필수품
A62	인명구조; 소방(사다리 E06C)
A62B	인명구조용의 기구, 장치 또는 방법(특히 의료용에 사용되는 밸브 A61M 39/00; 특히 물에서 쓰이는 인명구조 장치 또는 방법 B63C 9/00; 잠수장비 B63C 11/00; 특히 항공기에 쓰는 것, 예. 낙하산, 투출좌석 B64D; 특히 광산에서 쓰이는 구조장치 E21F 11/00)
A62B-1/08	.. 윈치 또는 풀리에 제동기구가 있는 것

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Microfluidic system including a bubble valve for regulating fluid flow through a microchannel 원문보기

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Microfluidic system including a bubble valve for regulating fluid flow through a microchannel 원문보기

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