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High density DNA array 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C12Q-001/68
  • C07H-021/04
  • C07K-001/04
  • G01N-015/14
출원번호 US-0425791 (2017-02-06)
등록번호 US-9944984 (2018-04-17)
발명자 / 주소
  • Drmanac, Radoje
  • Callow, Matthew J.
  • Drmanac, Snezana
  • Hauser, Brian K.
  • Yeung, George
출원인 / 주소
  • Complete Genomics, Inc.
대리인 / 주소
    Kilpatrick Townsend & Stockton LLP
인용정보 피인용 횟수 : 0  인용 특허 : 251

초록

A high density DNA array comprising a patterned surface, said surface comprising a pattern of small DNA binding regions separated by a non-DNA binding surface, wherein the DNA binding regions comprise DNA capture chemistry and the non-DNA binding surface does not have the DNA capture chemistry where

대표청구항

1. A high density DNA array comprising a patterned surface, said surface comprising a pattern of DNA binding regions separated by a non-DNA binding surface, andmore than 105 different DNAs comprising genomic sequences bound on the array at the DNA binding regions,wherein the DNA binding regions comp

이 특허에 인용된 특허 (251)

  1. Lee Linda ; Benson Scott C. ; Rosenblum Barnett B. ; Spurgeon Sandra L., 4, 7-Dichlororhodamine dyes.
  2. Menchen Steven M. (Fremont CA) Lee Linda G. (Palo Alto CA) Connell Charles R. (Redwood City CA) Hershey N. Davis (San Carlos CA) Chakerian Vergine (San Mateo CA) Woo Sam (Redwood City CA) Fung Steven, 4,7-dichlorofluorescein dyes as molecular probes.
  3. Barany, Francis; Liu, Jianzhao; Kirk, Brian W.; Zirvi, Monib; Gerry, Norman P.; Paty, Philip B., Accelerating identification of single nucleotide polymorphisms and alignment of clones in genomic sequencing.
  4. DuBridge Robert B. ; Albrecht Glenn ; Brenner Sydney,GBX ; Gryaznov Sergei M. ; McCurdy Sarah N., Adaptor-based sequence analysis.
  5. Hobbs ; Jr. Frank W. (Wilmington DE) Trainor George L. (Wilmington DE), Alkynylamino-nucleotides.
  6. Summerton James E. (Corvallis OR) Weller Dwight D. (Corvallis OR) Stirchak Eugene P. (Corvallis OR), Alpha-morpholino ribonucleoside derivatives and polymers thereof.
  7. Fung Steven (Palo Alto CA) Woo Sam L. (Redwood City CA) Smith Lloyd M. (South Pasadena CA), Amino-derivatized phosphite and phosphate linking agents, phosphoramidite precursors, and useful conjugates thereof.
  8. Nagasaka, Takeshi; Matsubara, Nagahide; Sasamoto, Hiromi; Tanaka, Noriaki, Amplification method of methylated or unmethylated nucleic acid.
  9. Dean,Frank B.; Lasken,Roger S.; Fang,Linhua; Faruqi,A. Fawad; Alsmadi,Osama A.; Driscoll,Mark D.; Hosono,Seiyu; Wisniewski,Michele; Song,Wanmin, Amplification of denatured and stabilized nucleic acids.
  10. Auerbach Jeffrey I., Amplification of nucleic acid molecules via circular replicons.
  11. Birkenmeyer Larry G. (Chicago IL) Carrino John J. (Gurnee IL) Dille Bruce J. (Antioch IL) Hu Hsiang-Yun (Libertyville IL) Kratochvil Jon D. (Kenosha WI) Laffler Thomas G. (Libertyville IL) Marshall R, Amplification of target nucleic acids using gap filling ligase chain reaction.
  12. Rothberg,Jonathan M.; Bader,Joel S.; Dewell,Scott B.; McDade,Keith; Simpson,John W.; Berka,Jan; Colangelo,Christopher M.; Weiner,Michael P., Apparatus and method for sequencing a nucleic acid.
  13. Ulmer,Kevin, Apparatus and methods for analyzing samples.
  14. Fodor Stephen P. A. (Palo Alto CA) Pirrung Michael C. (Durham NC) Read J. Leighton (Palo Alto CA) Stryer Lubert (Stanford CA), Array of oligonucleotides on a solid substrate.
  15. Balasubramanian, Shankar; Klenerman, David; Bentley, David, Arrayed biomolecules and their use in sequencing.
  16. Balasubramanian,Shankar; Klenerman,David; Barnes,Colin; Osborne,Mark Allen, Arrayed biomolecules and their use in sequencing.
  17. Fodor Stephen P.A. ; Stryer Lubert ; Read J. Leighton ; Pirrung Michael C., Arrays of materials attached to a substrate.
  18. Chee Mark ; Cronin Maureen T. ; Fodor Stephen P. A. ; Huang Xiaohua X. ; Hubbell Earl A. ; Lipshutz Robert J. ; Lobban Peter E. ; Morris MacDonald S. ; Sheldon Edward L., Arrays of nucleic acid probes on biological chips.
  19. Aldwin Lois (San Mateo CA) Madden Mark (Davis CA) Stemmer Willem P. C. (Los Gatos CA), Association peptides.
  20. De Mesmaeker Alain (Kaenerkinden CHX) Lebreton Jacques (Marseilles FRX) Waldner Adrian (Allschwil CHX) Cook Phillip D. (Carlsbad CA), Backbone modified oligonucleotide analogs.
  21. Sanghvi Yogesh S. (Carlsbad CA) Cook Phillip D. (Carlsbad CA), Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling.
  22. Bawendi Moungi G. ; Mikulec Frederick V. ; Sundar Vikram C., Biological applications of quantum dots.
  23. Sapolsky Ronald J. ; Lipshutz Robert J. ; Gingeras Thomas R., Capturing sequences adjacent to Type-IIs restriction sites for genomic library mapping.
  24. Koch, J.o slashed.rn Erland, Cascade nucleic acid amplification reaction.
  25. Pachuk Catherine J. ; Samuel Manoj ; Satishchandran C., Chain reaction cloning using a bridging oligonucleotide and DNA ligase.
  26. Beecher Jody E. ; Goldberg Martin J. ; McGall Glenn H., Chemical amplification for the synthesis of patterned arrays.
  27. Kool Eric T., Circular DNA vectors for synthesis of RNA and DNA.
  28. Landegren Ulf,SEX ; Kwiatkowski Marek,SEX, Circularizing nucleic acid probe able to interlock with a target sequence through catenation.
  29. Jean I. Montagu, Cleaning deposit devices that form microarrays and the like.
  30. Gibbs, Richard; Bradley, Allan; Cai, Wei-Wen, Clone-array pooled shotgun strategy for nucleic acid sequencing.
  31. Chee, Mark; Walt, David R., Combinatorial decoding of random nucleic acid arrays.
  32. Winkler James L. ; Fodor Stephen P. A. ; Buchko Christopher J. ; Ross Debra A. ; Aldwin Lois ; Modlin Douglas N., Combinatorial kit for polymer synthesis.
  33. Winkler James L. ; Fodor Stephen P. A. ; Buchko Christopher J. ; Ross Debra A. ; Aldwin Lois ; Modlin Douglas N., Combinatorial strategies for polymer synthesis.
  34. Matsuzaki,Hajime; Su,Xing; Walsh,Sean; Kennedy,Giulia; Mei,Rui, Complexity management of genomic DNA.
  35. Stuelpnagel, John R.; Chee, Mark S., Compositions and methods for repetitive use of genomic DNA.
  36. Hubbell Earl A. (Mt. View CA) Lipshutz Robert J. (Palo Alto CA) Morris Macdonald S. (San Jose CA) Winkler James L. (Palo Alto CA), Computer-aided engineering system for design of sequence arrays and lithographic masks.
  37. Hubbell Earl A. (Mt. View CA) Morris MacDonald S. (San Jose CA) Winkler James L. (Palo Alto CA), Computer-aided engineering system for design of sequence arrays and lithographic masks.
  38. Hubbell Earl A. ; Morris MacDonald S. ; Winkler James L., Computer-aided engineering system for design of sequence arrays and lithographic masks.
  39. Chee Mark S., Computer-aided visualization and analysis system for sequence evaluation.
  40. Chee Mark S., Computer-aided visualization and analysis system for sequence evaluation.
  41. David J. Lockhart ; Dirk Vetter DE; Martin Diggelmann CH, Conformationally-restricted peptide probe libraries.
  42. Gryaznov Sergei M. (San Mateo CA), Convergent synthesis of branched and multiply connected macromomolecular structures.
  43. Hollenberg Cornelis P. (Chopinstrasse 7 ; 4000 Dusseldorf DEX) di Mauro Ernesto (Via Andrea Fulvio 10 ; 00162 Rome ITX), DNA and DNA technology for the construction of networks to be used in chip construction and chip production (DNA-chips).
  44. Kambara Hideki,JPX ; Okano Kazunori,JPX, DNA probe array.
  45. Macevicz Stephen C., DNA sequencing by parallel oligonucleotide extensions.
  46. Macevicz Stephen C., DNA sequencing by parallel oligonucleotide extensions.
  47. Overbeck James W. ; Flowers Peter T. ; Montagu Jean I. ; Mace Myles L. ; Honkanen Peter, Depositing fluid specimens on substrates, resulting ordered arrays, techniques for deposition of arrays.
  48. Sundberg Steven A. (San Francisco CA) Fujimoto David (Mountain View CA), Derivatization of solid supports and methods for oligomer synthesis.
  49. Sundberg Steven A. ; Jacobs Jeffrey W. ; Schullek John R. ; McGall Glenn H. ; Mirzabekov Andrei ; Timofeey Edward,RUX ; Fujimoto David ; Holmes Christopher P. ; Yang Hua, Derivatization of solid supports and methods for oligomer synthesis.
  50. Mark S. Chee ; Kevin Gunderson, Detection of nucleic acid amplification reactions using bead arrays.
  51. Whiteley Norman M. (San Carlos CA) Hunkapiller Michael W. (San Carlos CA) Glazer Alexander N. (Orinda CA), Detection of specific sequences in nucleic acids.
  52. Huber Erasmus (Garching) Mhlegger Klaus (Polling) von der Eltz Herbert (Weilheim) Zink Bruno (Staffelsee DEX), Digoxigenin derivatives and use thereof.
  53. Mirkin,Chad A.; Demers,Linette; Ginger,David S., Direct write nanolithographic deposition of nucleic acids from nanoscopic tips.
  54. Drmanac, Radoje T.; Callow, Matthew, Efficient arrays of amplified polynucleotides.
  55. Drmanac, Radoje T; Callow, Matthew, Efficient arrays of amplified polynucleotides.
  56. Hall ; Jr. Bertie Forrest (Ann Arbor MI) Brackman Phillip D. (Whitmore Lake MI), Electrode material for a spark plug.
  57. Lee Linda G. ; Spurgeon Sandra L. ; Rosenblum Barnett, Energy transfer dyes with enchanced fluorescence.
  58. Drmanac, Radoje; Drmanac, Snezana; Kita, David; Cooke, Cory; Xu, Chongjun, Enhanced sequencing by hybridization using pools of probes.
  59. Lockhart David J. ; Warrington Janet A. ; Nair Archana, Expression profiles in adult and fetal organs.
  60. Fawcett Nigel,GBX ; Knowles Richard,GBX, Forming an erosion resistant coating on an electrode.
  61. Macevicz Stephen C., Gene expression analysis.
  62. Drmanac, Radoje, Genome sequence analysis using tagged amplicons.
  63. Drmanac, Radoje T.; Callow, Matthew; Drmanac, Snezana, High throughput genome sequencing on DNA arrays.
  64. Drmanac, Radoje; Callow, Matthew J.; Drmanac, Snezana, High throughput genome sequencing on DNA arrays.
  65. Bawendi Moungi ; Jensen Klavs F. ; Dabbousi Bashir O.,SAX ; Rodriguez-Viejo Xavier,ESX ; Mikulec Frederic Victor, Highly luminescent color-selective nano-crystalline materials.
  66. Kool Eric T., Highly sensitive multimeric nucleic acid probes.
  67. Carl T. Wittwer ; Mark G. Herrmann, Homogeneous multiplex hybridization analysis by color and Tm.
  68. Holmes Christopher P. (Sunnyvale CA), Immobilized molecular synthesis of systematically substituted compounds.
  69. Auerbach Jeffrey I., In vitro amplification of nucleic acid molecules via circular replicons.
  70. Andrew Griffiths GB; Dan Tawfik GB, In vitro sorting method.
  71. Deugau Kenneth V. (Kingston CAX) Unrau Paul (Deep River CAX), Indexing linkers.
  72. Deugau Kenneth Victor,CAX ; Unrau Paul,CAX, Indexing linkers.
  73. Pirrung Michael C. (Durham NC) Read J. Leighton (Palo Alto CA) Fodor Stephen P. A. (Palo Alto CA) Stryer Lubert (Stanford CA), Large scale photolithographic solid phase synthesis of an array of polymers.
  74. Pirrung Michael C. (Durham NC) Read J. Leighton (Palo Alto CA) Fodor Stephen P. A. (Palo Alto CA) Stryer Lubert (Stanford CA), Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof.
  75. Johann, Timothy W.; Park, Sang Chul, Linear microarrays.
  76. Treadway, Joseph A.; Zehnder, Donald A.; Schrier, Marc D., Luminescent nanoparticles and methods for their preparation.
  77. Khodadoust Mehran, MTbx protein and nucleic acid molecules and uses therefor.
  78. Albrecht Glenn ; Brenner Sydney,GBX ; DuBridge Robert B. ; Lloyd David H. ; Pallas Michael C., Massively parallel signature sequencing by ligation of encoded adaptors.
  79. Brennan Thomas M., Method and apparatus for conducting an array of chemical reactions on a support surface.
  80. Brennan Thomas M. (San Francisco CA), Method and apparatus for conducting an array of chemical reactions on a support surface.
  81. Matson Robert S. (Orange CA) Coassin Peter J. (San Juan Capistrano CA) Rampal Jang B. (Yorba Linda CA) Southern Edwin M. (Kidlington GB2), Method and apparatus for creating biopolymer arrays on a solid support surface.
  82. Stern David (Mt. View CA) Fiekowsky Peter (Los Altos CA), Method and apparatus for detection of fluorescently labeled materials.
  83. Trulson Mark (Santa Clara CA) Stern David (Mountain View CA) Fiekowsky Peter (Los Altos CA) Rava Richard (Palo Alto CA) Walton Ian (Menlo Park CA) Fodor Stephen P. A. (Palo Alto CA), Method and apparatus for imaging a sample on a device.
  84. Trulson Mark ; Stern David ; Fiekowsky Peter ; Rava Richard ; Walton Ian ; Fodor Stephen P. A., Method and apparatus for imaging a sample on a device.
  85. Butler, John H.; Brennan, Thomas M., Method and apparatus for in situ synthesis on a solid support.
  86. Fodor Stephen P. A. (Palo Alto CA) Mazzola Laura T. (Redwood City CA), Method and apparatus for measuring binding affinity.
  87. Henderson, Eric; Mosher, Curtis; Lynch, Michael P., Method and apparatus for solid state molecular analysis.
  88. Henderson,Eric; Mosher,Curtis; Lynch,Michael P., Method and apparatus for solid state molecular analysis.
  89. Fire Andrew (Baltimore MD) Xu Si-Qun (Baltimore MD), Method for constructing an oligonucleotide concatamer library by rolling circle replication.
  90. Cantor, Charles R; Siddiqi, Fouad A, Method for de novo detection of sequences in nucleic acids: target sequencing by fragmentation.
  91. Hefti John, Method for detecting and classifying nucleic acid hybridization.
  92. Moore David J. (Fostoria OH) Barrett William A. (Bradner OH), Method for manufacturing a center electrode for a spark plug.
  93. Adams Christopher P. (Winter Hill MA) Kron Stephen Joseph (Boston MA), Method for performing amplification of nucleic acid with two primers bound to a single solid support.
  94. Brennan Thomas M., Method for polymer synthesis using arrays.
  95. Drmanac, Radoje, Method for sequencing polynucleotides by forming separate fragment mixtures.
  96. Ronaghi, Mostafa, Method of DNA sequencing.
  97. Fodor Stephen P. A. ; Lipshutz Robert J. ; Huang Xiaohua, Method of Identifying a Base in a Nucleic Acid.
  98. Bruchez Marcel P. ; Daniels R. Hugh ; Empedocles Stephen A. ; Phillips Vince E. ; Wong Edith Y. ; Zehnder Donald A., Method of detecting an analyte in a sample using semiconductor nanocrystals as a detectable label.
  99. Fodor Stephen P.A. ; Solas Dennis W. ; Dower William J., Method of detecting nucleic acids.
  100. Drmanac Radoje T. (Beograd YUX) Crkvenjakov Radomir B. (Beograd YUX), Method of determining an ordered sequence of subfragments of a nucleic acid fragment by hybridization of oligonucleotide.
  101. Xiang Qi ; Lin Ming-Ren, Method of manufacturing a polysilicon gate having a dimension below the photolithography limitation.
  102. Goldberg Martin J. ; Rava Richard P., Method of manufacturing biological chips.
  103. Langmore, John P.; Makarov, Vladimir L., Method of producing a DNA library using positional amplification based on the use of adaptors and nick translation.
  104. Brenner, Sydney, Method of screening for genetic polymorphism.
  105. Nyren P.ang.l,SEX ; Uhlen Mathias,SEX ; Ronaghi Mostafa,SEX, Method of sequencing DNA.
  106. Rothberg Jonathan M. ; Bader Joel S., Method of sequencing a nucleic acid.
  107. Rothberg,Jonathan M.; Bader,Joel S.; Dewell,Scott B.; McDade,Keith; Simpson,John W.; Berka,Jan; Colangelo,Christopher M., Method of sequencing a nucleic acid.
  108. Rothberg,Jonathan M.; Bader,Joel S.; Dewell,Scott B.; McDade,Keith; Simpson,John W.; Berka,Jan; Colangelo,Christopher M., Method of sequencing a nucleic acid.
  109. Drmanac Radoje T. (Belgrade YUX) Crkvenjakov Radomir B. (Belgrade YUX), Method of sequencing by hybridization of oligonucleotide probes.
  110. Drmanac Radoje T. (Zvecanska 46 Beograd 11000) Crkvenjakov Radomir B. (Bulevar JNA 118 Beograd YUX 11000), Method of sequencing of genomes by hybridization of oligonucleotide probes.
  111. William Dower ; Ronald W. Barrett ; Mark A. Gallop ; Michael C. Needels, Method of synthesizing diverse collections of oligomers.
  112. Schon Eric A., Method to detect mutations in a nucleic acid using a hybridization-ligation procedure.
  113. Drmanac Radoje, Methods and apparatus for DNA sequencing and DNA identification.
  114. Quake, Stephen; Volkmuth, Wayne; Unger, Marc, Methods and apparatus for analyzing polynucleotide sequences.
  115. Brennan Thomas M. (2000 Broadway ; No. 705 San Francisco CA 94115) Heyneker Herbert L. (360 Forest Ave. ; No. 506 Palo Alto CA 94301), Methods and compositions for determining the sequence of nucleic acids.
  116. Radoje Drmanac, Methods and compositions for efficient nucleic acid sequencing.
  117. Drmanac, Radoje T., Methods and compositions for large-scale analysis of nucleic acids using DNA deletions.
  118. Drmanac, Radoje; Peters, Brock A.; Alexeev, Andrei; Hong, Peter, Methods and compositions for long fragment read sequencing.
  119. Deem, Michael W.; Park, Jeong-Man; Zhou, Hao, Methods and compositions for polytopic vaccination.
  120. Dahl, Fredrik; Drmanac, Radoje; Sparks, Andrew, Methods and oligonucleotide designs for insertion of multiple adaptors employing selective methylation.
  121. Dahl, Fredrik; Drmanac, Radoje; Sparks, Andrew, Methods and oligonucleotide designs for insertion of multiple adaptors into library constructs.
  122. Zailin Yu ; Zaoyuan Peng ; Qianjin Hu, Methods for amplifying and detecting multiple polynucleotides on a solid phase support.
  123. Drmanac Radoje T., Methods for analyzing a target nucleic acid using immobilized heterogeneous mixtures of oligonucleotide probes.
  124. Sapolsky, Ronald J.; Lipshutz, Robert J.; Gingeras, Thomas R., Methods for analyzing nucleic acids using a type IIs restriction endonuclease.
  125. Rava Richard P. ; Fodor Stephen P.A. ; Trulson Mark, Methods for concurrently processing multiple biological chip assays.
  126. Drmanac, Radoje; Callow, Matthew J.; Drmanac, Snezana; Hauser, Brian K.; Yeung, George, Methods for making single molecule arrays.
  127. Weissman, Sherman; Lasken, Roger, Methods for selectively isolating DNA using rolling circle amplification.
  128. Drmanac Radoje T. ; Drmanac Snezana ; Hou Aaron ; Hauser Brian, Methods for sequencing repetitive sequences and for determining the order of sequence subfragments.
  129. Auerbach Jeffrey I. (13109 Jasmine Hill Terr. Rockville MD 20850), Methods for the isothermal amplification of nucleic acid molecules.
  130. Lexow,Preben, Methods of cloning and producing fragment chains with readable information content.
  131. Rajotte Daniel ; Pasqualini Renata ; Ruoslahti Erkki, Methods of identifying lung homing molecules using membrane dipeptidase.
  132. Kool Eric T. (Rochester NY), Methods of making single-stranded circular oligonucleotides.
  133. Yeung Anthony T., Mismatch endonuclease and its use in identifying mutations in targeted polynucleotide strands.
  134. Heller Michael J. (Encinitas CA) Tu Eugene (San Diego CA) Butler William F. (Carlsbad CA), Molecular biological diagnostic systems including electrodes.
  135. Lizardi Paul M., Molecular cloning using rolling circle amplification.
  136. Montagu Jean I., Moving magnet scanner.
  137. Iyer Rajkumar Siva ; Su Sheng-Hui ; Inamdar Anita ; Kalra Krishan L., Multifunctional linking reagents for synthesis of branched oligomers.
  138. Lizardi Paul M., Multiple displacement amplification.
  139. Chandler, Van S.; Fulton, R. Jerrold; Chandler, Mark B., Multiplexed analysis of clinical specimens apparatus and method.
  140. Fan, Jian-Bing; Stuelpnagel, John R.; Chee, Mark S., Multiplexed detection of analytes.
  141. Mirkin, Chad A.; Letsinger, Robert L.; Mucic, Robert C.; Storhoff, James J.; Elghanian, Robert; Taton, Thomas A., Nanoparticles having oligonucleotides attached thereto and uses therefor.
  142. Ts\o Paul O. P. (2117 Folkstone Rd. Lutherville MD 21093) Miller Paul S. (225 Hopkins Rd. Baltimore MD 21212), Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof.
  143. Khanna Pyare (Mountain View CA) Ullman Edwin F. (Atherton CA), Novel ether substituted fluorescein polyamino acid compounds as fluorescers and quenchers.
  144. Lipshutz Robert J. ; Morris MacDonald S. ; Chee Mark S. ; Gingeras Thomas R., Nucleic acid affinity columns.
  145. Drmanac, Radoje, Nucleic acid analysis by random mixtures of non-overlapping fragments.
  146. Drmanac, Radoje, Nucleic acid analysis by random mixtures of non-overlapping fragments.
  147. Brenner, Sydney, Nucleic acid analysis using sequence tokens.
  148. Sabanayagam Chandran R. ; Sano Takeshi ; Misasi John ; Hatch Anson ; Cantor Charles, Nucleic acid arrays and methods of synthesis.
  149. Fan, Jian-Bing; Fu, Xiang-Dong, Nucleic acid detection methods using universal priming.
  150. Guilfoyle Richard A. ; Guo Zhen, Nucleic acid indexing.
  151. Urdea Michael S. (Alamo CA) Warner Brian (Martinez CA) Horn Thomas (Berkeley CA), Nucleic acid multimers and amplified nucleic acid hybridization assays using same.
  152. Drmanac, Radoje, Nucleic acid sequence analysis from combined mixtures of amplified fragments.
  153. Drmanac, Radoje; Callow, Matthew, Nucleic acid sequencing and process.
  154. Cruickshank Kenneth (Lisle IL), Nucleotide compositions with linking groups.
  155. Drmanac, Radoje, Nucleotide sequence from amplicon subfragments.
  156. Benner Steven A. (Grossmannstrasse 16 ; #7 CH-8049 Zurich CHX), Oligonucleotide analogs containing sulfur linkages.
  157. Gryaznov Sergei M. (San Mateo CA) Lloyd David H. (Daly City CA), Oligonucleotide clamps having diagnostic applications.
  158. Miyoshi Kenichi (Hiroshima JPX) Suzuki Masanori (Hiroshima JPX) Fuwa Toru (Hiroshima JPX), Oligonucleotide derivatives and production thereof.
  159. Matson Robert S. ; Coassin Peter J. ; Rampal Jang B. ; Caskey Charles Thomas, Oligonucleotide repeat arrays.
  160. Weiss Shimon ; Bruchez ; Jr. Marcel ; Alivisatos Paul, Organo Luminescent semiconductor nanocrystal probes for biological applications and process for making and using such p.
  161. Shimon Weiss ; Marcel Bruchez, Jr. ; Paul Alivisatos, Organo luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes.
  162. Wong,Wing H., Parallel polynucleotide sequencing method.
  163. Seeman Nadrian ; Winfree Erik ; Liu Furong ; Wenzler Savin Lisa, Periodic two and three dimensional nucleic acid structures.
  164. Cook Phillip D. (Carlsbad CA) Acevedo Oscar (San Diego CA) Hebert Normand (San Marcos CA), Phosphoramidate and phosphorothioamidate oligomeric compounds.
  165. Stephen P. A. Fodor ; Lubert Stryer ; J. Leighton Read ; Michael C. Pirrung, Polymer arrays.
  166. Lyle J. Arnold ; Samuel P. Sawan ; Paul H. Lee, Polymer coated surfaces for microarray applications.
  167. Holmes Christopher P. (521 Pine Ave. Sunnyvale CA 94086), Polymer reversal on solid surfaces.
  168. Holmes Christopher P. (Sunnyvale CA), Polymer reversal on solid surfaces.
  169. Chenchik Alex ; Siebert Paul, Polymeric arrays and methods for their use in binding assays.
  170. Sapolsky Ronald J. ; Lipshutz Robert J., Polymorphism detection.
  171. Newman Peter J. (Shorewood WI) Aster Richard H. (Milwaukee WI), Polymorphism of human platelet membrane glycoprotein IIIa and diagnostic and therapeutic applications thereof.
  172. Balasubramanian, Shankar, Polynucleotide sequencing.
  173. Bawendi, Moungi; Stott, Nathan E., Preparation of nanocrystallites.
  174. Mark R. Alfenito, Preparation of pools of nucleic acids based on representation in a sample.
  175. Pease R. Fabian (Stanford CA) McGall Glenn (Mountain View CA) Goldberg Martin J. (San Jose CA) Rava Richard P. (Palo Alto CA) Fodor Stephen P. A. (Palo Alto CA) Goss Virginia (Santa Barbara CA) Strye, Printing molecular library arrays using deprotection agents solely in the vapor phase.
  176. Pease R. Fabian ; McGall Glenn ; Goldberg Martin J. ; Rava Richard P. ; Fodor Stephen P. A. ; Goss Virginia ; Stryer Lubert ; Winkler James L., Printing oligonucleotide arrays using deprotection agents solely in the vapor phase.
  177. Mathies Richard A. (El Cerrito CA) Glazer Alexander (Orinda CA) Ju Jingyue (Berkeley CA), Probes labelled with energy transfer coupled dyes.
  178. Sibson David Ross,GBX, Process for categorizing nucleotide sequence populations.
  179. Yau Eric K. (Kirkland WA), Process for preparing phosphorothioate oligonucleotides.
  180. Brock Phillip Joe (Sunnyvale CA) Hinsberg William Dinan (Fremont CA) Labadie Jeffrey William (Sunnyvale CA) McGall Glenn (Mountain View CA) Wallraff Gregory Michael (Morgan Hill CA), Process for synthesizing chemical compounds.
  181. Hltke Hans-Joachim (Tutzing DEX) Seibl Rudolf (Penzberg DEX) Schmitz Gudrun (Bernried DEX) Schler Hans R. (Gttingen DEX) Kessler Christoph (Mnchen DEX) Mattes Ralf (Stuttgart DEX), Process for the detection of nucleic acids.
  182. Holtke Hans-Joachim (Tutzing DEX) Seibl Rudolf (Penzburg DEX) Schmitz Gudrun (Bernried DEX) Scholer Hans Robert (Gottingen DEX) Kessler Christoph (Munchen DEX) Mattes Ralf (Stuttgart DEX), Process for the detection of nucleic acids.
  183. Hltke Hans J. (Kirchenstrasse 1 D-8132 Tutzing DEX) Seibl Rudolf (Saalangerstrasse 46 D-8122 Penzberg DEX) Kessler Christoph (Fraunhofer Strasse 12 D-8000 Mnchen 5 DEX) Mattes Ralf (Friedrich-Zundel-, Process for the highly specific detection of nucleic acids in solid.
  184. Stephen P. A. Fodor ; Dennis W. Solas ; William J. Dower, Products for detecting nucleic acids.
  185. Wang Bruce, Quantitative microarray hybridizaton assays.
  186. Qiao,Tiecheng A.; Chari,Krishnan; Vizard,Douglas L., Random array of micro-spheres for the analysis of nucleic acids.
  187. Church, George M.; Mitra, Robi D., Replica amplification of nucleic acid arrays.
  188. George M. Church, Replica amplification of nucleic acid arrays.
  189. George M. Church ; Rob Mitra, Replica amplification of nucleic acid arrays.
  190. Guire, Patrick E.; Swanson, Melvin J., Replicable probe array.
  191. Hunkapiller Michael W. ; Richards John H., Restriction enzyme mediated adapter.
  192. Mahtani Melanie M., Rolling circle amplification assay for nucleic acid analysis.
  193. Christian, Allen T.; Pattee, Melissa S.; Attix, Cristina M.; Tucker, James D., Rolling circle amplification detection of RNA and DNA.
  194. Kumar, Gyanendra; Abarz?a, Patricio, Rolling circle amplification of RNA.
  195. Landegren, Ulf, Rolling circle replication of padlock probes.
  196. Lizardi Paul M.,MXX, Rolling circle replication reporter systems.
  197. Paul M. Lizardi MX, Rolling circle replication reporter systems.
  198. Kool Eric T., Rolling circle synthesis of oligonucleotides and amplification of select randomized circular oligonucleotides.
  199. Fiekowsky Peter ; Bartell Dan M., Scanned image alignment systems and methods.
  200. Zabeau Marc,BEX ; Vos Pieter,NLX, Selective restriction fragment amplification: fingerprinting.
  201. Drmanac, Radoje; Callow, Matthew J.; Hauser, Brian K.; Yeung, George, Self-assembled single molecule arrays and uses thereof.
  202. Drmanac, Radoje; Callow, Matthew J.; Hauser, Brian K.; Yeung, George, Self-assembled single molecule arrays and uses thereof.
  203. Weiss Shimon ; Bruchez Marcel ; Alivisatos Paul, Semiconductor nanocrystal probes for biological applications and process for making and using such probes.
  204. Neuschafer Dieter,CHX ; Duveneck Gert Ludwig,GBX ; Pawlak Michael,GBX ; Pieles Uwe,GBX ; Budach Wolfgang,CHX, Sensor platform and method for the parallel detection of a plurality of analytes using evanescently excited luminescence.
  205. Drmanac, Radoje, Sequencing using a predetermined coverage amount of polynucleotide fragments.
  206. Lizardi Paul M. ; Huang Xiaohua, Single molecule analysis target-mediated ligation of bipartite primers.
  207. Drmanac, Radoje T.; Callow, Matthew J.; Drmanac, Snezana; Hauser, Brian K.; Yeung, George, Single molecule arrays for genetic and chemical analysis.
  208. Drmanac, Radoje; Callow, Matthew J.; Drmanac, Snezana; Hauser, Brian K.; Yeung, George, Single molecule arrays for genetic and chemical analysis.
  209. Drmanac, Radoje; Callow, Matthew J.; Drmanac, Snezana; Hauser, Brian K.; Yeung, George, Single molecule arrays for genetic and chemical analysis.
  210. Drmanac, Radoje; Callow, Matthew J.; Drmanac, Snezana; Hauser, Brian K.; Yeung, George, Single molecule arrays for genetic and chemical analysis.
  211. Barany Francis (Baltimore MD), Six base oligonucleotide linkers and methods for their use.
  212. Peponnet Christine,FRX, Solid support for solid phase amplification and sequencing and method for preparing the same nucleic acid.
  213. Franks Harry E. (60 Beacon St. Chestnut Hill MA 02167), Spark plug.
  214. Kanao, Keiji; Hori, Tsunenobu, Spark plug and its manufacturing method.
  215. Chang Chin-Fong ; Taylor Richard Dale ; Franz Lee Randall ; Leone Edgar Arnold, Spark plug electrode having iridium based sphere and method for manufacturing same.
  216. Oshima Takafumi (Nagoya JPX), Spark plug for use in an internal combustion engine.
  217. Lykowski, James D.; Levina, Iryna, Spark plug having spark portion provided with a base material and a protective material.
  218. Boehler Jeffrey T. ; Zulauf Gary B., Spark plug shell having a bimetallic ground electrode spark plug incorporating the shell, and method of making same.
  219. Barrett Ronald W. (Sunnyvale CA) Pirrung Michael C. (Durham NC) Stryer Lubert (Stanford CA) Holmes Christopher P. (Sunnyvale CA) Sundberg Steven A. (San Francisco CA), Spatially-addressable immobilization of anti-ligands on surfaces.
  220. Barrett Ronald W. (Sunnyvale CA) Pirrung Michael C. (Durham NC) Stryer Lubert (Stanford CA) Holmes Christopher P. (Sunnyvale CA) Sundberg Steven A. (San Francisco CA), Spatially-addressable immobilization of anti-ligands on surfaces.
  221. Barrett Ronald W. (Sunnyvale CA) Pirrung Michael C. (Durham NC) Stryer Lubert (Stanford CA) Holmes Christopher P. (Sunnyvale CA) Sundberg Steven A. (San Francisco CA), Spatially-addressable immobilization of anti-ligands on surfaces.
  222. Bergot B. John (Redwood City CA) Chakerian Vergine (San Mateo CA) Connell Charles R. (Redwood City CA) Eadie J. Scott (Indianapolis IN) Fung Steven (Palo Alto CA) Hershey N. Davis (San Carlos CA) Lee, Spectrally resolvable rhodamine dyes for nucleic acid sequence determination.
  223. Fodor, Stephen P. A.; Pirrung, Michael C.; Stryer, Lubert; Read, J. Leighton, Support bound probes and methods of analysis using the same.
  224. J. Leighton Read ; Stephen P. A. Fodor ; Lubert Stryer ; Michael C. Pirrung, Support bound probes and methods of analysis using the same.
  225. Southern Edwin M. (Oxford GB3) Maskos Uwe (Oxford GB3), Support-bound oligonucleotides.
  226. Coassin Peter J. (San Juan Capistrano CA) Matson Robert (Orange CA) Rampal Jang (Yorba Linda CA), Surface activated organic polymers useful for location - specific attachment of nucleic acids, peptides, proteins and ol.
  227. Adams, Edward William; Bruchez, Jr., Marcel Pierre, Surface-modified semiconductive and metallic nanoparticles having enhanced dispersibility in aqueous media.
  228. McGall Glenn H. ; Nam Ngo Quoc, Synthesis of oligonucleotide arrays using photocleavable protecting groups.
  229. Barnes,Colin, Synthesis of spatially addressed molecular arrays.
  230. Bridgham, John; Corcoran, Kevin; Golda, George; Pallas, Michael C.; Brenner, Sydney, System and apparatus for sequential processing of analytes.
  231. Fan, Wei; Wang, Haixun; Yu, Philip S., System and method for sequence-based subspace pattern clustering.
  232. Stephen P.A. Fodor ; James L. Winkler, System for determining receptor-ligand binding affinity.
  233. Rabbani,Elazar; Stavrianopoulos,Jannis G.; Kirtikar,Dollie; Johnston,Kenneth H.; Thalenfeld,Barbara E., System, array and non-porous solid support comprising fixed or immobilized nucleic acids.
  234. Stern David, Systems and methods for detection of labeled materials.
  235. Walt David R. ; Michael Karri L., Target analyte sensors utilizing Microspheres.
  236. Egholm Michael ; Chen Caifu, Template-dependent ligation with PNA-DNA chimeric probes.
  237. Drmanac, Radoje T.; Callow, Matthew; Drmanac, Snezana, Two-adaptor library for high-throughput sequencing on DNA arrays.
  238. Summerton, James E.; Weller, Dwight D., Uncharged morpholino-based polymers having achiral intersubunit linkages.
  239. Lizardi Paul M.,MXX ; Caplan Michael, Unimolecular segment amplification and sequencing.
  240. Lizardi Paul M.,MXX ; Caplan Michael, Unimolecular segment amplification and sequencing.
  241. Lizardi, Paul M., Unimolecular segment amplification and sequencing.
  242. Cantor, Charles R.; Siddiqi, Fouad A., Use of nucleotide analogs in the analysis of oligonucleotide mixtures and in highly multiplexed nucleic acid sequencing.
  243. Schwartz Dennis E. (Redmond WA), Use of volume exclusion agents for the enhancement of in situ hybridization.
  244. Fodor Stephen P. A. (Palo Alto CA) Stryer Lubert (Stanford CA) Pirrung Michael C. (Durham NC) Read J. Leighton (Palo Alto CA), Very large scale immobilized polymer synthesis.
  245. Pirrung Michael C. ; Read J. Leighton ; Fodor Stephen P. A. ; Stryer Lubert, Very large scale immobilized polymer synthesis.
  246. Winkler James L. (Palo Alto CA) Fodor Stephen P. A. (Palo Alto CA) Buchko Christopher J. (Palo Alto CA) Ross Debra A. (Fremont CA) Aldwin Lois (San Mateo CA), Very large scale immobilized polymer synthesis using mechanically directed flow paths.
  247. Bawendi Moungi G. ; Mikulec Frederick V. ; Lee Jin-Kyu,KRX, Water-soluble fluorescent nanocrystals.
  248. Moungi G. Bawendi ; Frederick V. Mikulec ; Jin-Kyu Lee KR, Water-soluble fluorescent nanocrystals.
  249. Bawendi Moungi G. ; Mikulec Frederic V. ; Lee Jin-Kyu,KRX, Water-soluble fluorescent semiconductor nanocrystals.
  250. Moungi G. Bawendi ; Frederick V. Mikulec ; Jin-Kyu Lee KR, Water-soluble thiol-capped nanocrystals.
  251. Lee Linda (Mountain View CA), Xanthene dyes that emit to the red of fluorescein.
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