최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
DataON 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
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Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0062865 (2013-10-24) |
등록번호 | US-9957553 (2018-05-01) |
발명자 / 주소 |
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출원인 / 주소 |
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대리인 / 주소 |
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인용정보 | 피인용 횟수 : 0 인용 특허 : 356 |
This invention provides biochip cartridges and instrument devices for the detection and/or analysis of target analytes from patient samples.
1. A biochip cartridge for detecting a target analyte, the biochip cartridge comprising: A) a bottom substrateB) a top plate;C) a liquid reagent module comprising a plurality of blisters; andD) an external housing having open areas over at least one of the plurality of blisters. 2. A biochip cartrid
1. A biochip cartridge for detecting a target analyte, the biochip cartridge comprising: A) a bottom substrateB) a top plate;C) a liquid reagent module comprising a plurality of blisters; andD) an external housing having open areas over at least one of the plurality of blisters. 2. A biochip cartridge according to claim 1, wherein said top plate comprises a conductive surface. 3. A biochip cartridge according to claim 1, wherein said top plate comprises at least one fluid hole spatially corresponding to said bottom substrate. 4. A biochip cartridge according to claim 1, wherein said bottom substrate comprises a dried assay reagent. 5. A biochip cartridge according to claim 1, wherein said liquid reagent module further comprises an aliquot of magnetic capture beads. 6. A biochip cartridge according to claim 3, wherein at least one of said fluid holes is configured to dispense a fluid assay reagent at a location remote from a blister comprising said reagent. 7. A biochip cartridge according to claim 1, wherein said external housing is asymmetrically shaped. 8. A biochip cartridge according to claim 4, wherein said dried assay reagent is selected from the group consisting of: dNTPs, PCR primers, a nucleic acid polymerase, an exonuclease, labelled signaling probes, and a combination thereof. 9. A biochip cartridge according to claim 1, wherein said external housing further comprises a cartridge identification tag. 10. A biochip cartridge according to claim 1, wherein the plurality of blisters comprise fluid assay reagents selected from the group consisting of: water, an immiscible fluid, a lysis buffer, a binding buffer, an elution buffer, and a reconstitution buffer. 11. A biochip cartridge according to claim 1, wherein all or part of the top plate is coated with a hydrophilic, oleophobic material. 12. A biochip cartridge according to claim 1, wherein said top plate comprises one or more entry ports configured to allow fluid flow into said reaction chamber. 13. A biochip cartridge according to claim 1, wherein said top plate further comprises one or more vents configured to reduce air bubble formation within the reaction chamber and/or remove any air bubbles that do form within the reaction chamber. 14. A biochip cartridge for detecting a target analyte, the biochip cartridge comprising: a) a liquid reagent module comprising a blister connected to a sphere blister by a channel;b) a top plate; andc) a bottom substrate comprising a printed circuit board. 15. A biochip cartridge according to claim 14, wherein the sphere blister comprises a steel ball bearing. 16. A biochip cartridge according to claim 14, wherein the sphere blister comprises a septum. 17. A biochip cartridge according to claim 14, wherein the blister is connected to the sphere blister by the channel blocked by a breakable seal. 18. A biochip cartridge according to claim 14, wherein the liquid reagent module further comprises magnetic capture beads. 19. A biochip cartridge according to claim 14, wherein the liquid reagent module further comprises a waste chamber. 20. A biochip cartridge according to claim 14, wherein the liquid reagent module further comprises a porous filter.
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