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A method of preparing a distal femur for a knee joint implant includes mounting a patient-specific bone engagement surface of a femoral alignment guide on a complementary surface of a distal femur of a patient. A plurality of alignment pins is inserted through a corresponding plurality of guiding bo

A method of preparing a distal femur for a knee joint implant includes mounting a patient-specific bone engagement surface of a femoral alignment guide on a complementary surface of a distal femur of a patient. A plurality of alignment pins is inserted through a corresponding plurality of guiding bores of the femoral alignment guide into the distal femur. A cutting guide is mounted on first and second alignment pins of the plurality of alignment pins, and a first resection of the distal femur is made using the cutting guide while cutting through the femoral alignment guide.

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1. An orthopedic system comprising: a patient-specific alignment guide operable for preparing a bone of a patient during joint arthroplasty, the alignment guide including a patient-specific bone engagement surface configured to be complementary to a surface of the bone of the patient, the alignment

1. An orthopedic system comprising: a patient-specific alignment guide operable for preparing a bone of a patient during joint arthroplasty, the alignment guide including a patient-specific bone engagement surface configured to be complementary to a surface of the bone of the patient, the alignment guide including a plurality of guiding bores;a plurality of alignment members receivable through corresponding guiding bores for attaching the alignment guide to the bone;a cutting block; andone or more pins, wherein a one of the plurality of alignment members or the one or more pins are cannulated and configured to receive the other of the plurality of alignment members or the one or more pins to mount the cutting block into a desired position relative to the bone. 2. The system of claim 1, wherein the alignment members are configured to be cut off during a first resection of the bone. 3. The system of claim 2, wherein the first resection is to a distal portion of the bone. 4. The system of claim 3, wherein the cutting block is configured to facilitate a second resection of the bone. 5. The system of claim 4, wherein the second resection is to an anterior portion of the bone. 6. The system of claim 4, wherein the alignment members are configured to be cut off during the second resection of the bone. 7. The system of claim 4, wherein the alignment members are configured to be further cut off during both the first resection of the bone and the second resection of the bone. 8. The system of claim 2, wherein the cutting block patient-specific alignment guide is configured with a slot configured to facilitate the first resection. 9. The system of claim 2, wherein the alignment members are configured to be cut off during the first resection of the bone. 10. The system of claim 2, wherein the first resection cuts through the patient-specific alignment guide. 11. The system of claim 1, wherein the alignment members are resorbable. 12. The system of claim 1, wherein the patient-specific alignment guide comprises a tibial alignment guide and the bone comprises a tibia, the tibial alignment guide including: a first portion engageable with a proximal surface of the tibia, the first portion defining a first and a second of the corresponding guiding bores and an opening between the first and the second of the corresponding guiding bores; anda second portion engageable with an anterior surface of the tibia, the second portion defining a third and a fourth of the corresponding guiding bores. 13. The system of claim 1, wherein the plurality of guiding bores includes a pair of oblique guiding bores oriented at an oblique angle relative to a surface of the distal femur. 14. The system of claim 1, wherein the patient-specific alignment guide comprises a femoral alignment guide and the bone comprises a femur, the femoral alignment guide including: a first portion engageable with a distal surface of a femur, the first portion defining a first and a second of the corresponding guiding bores; anda second portion engageable with an anterior surface of the tibia, the second portion defining a third and a fourth of the corresponding guiding bores. 15. The system of claim 14, wherein the femoral alignment guide is configured to be cut through during a resection of the femur. 16. The system of claim 14, wherein the cutting block comprises at least one of a distal cutting block mountable to at least a first of the plurality of alignment members and a 4-in-1 cut guide mountable to at least a second of the plurality of alignment members. 17. The system of claim 1, wherein the patient-specific alignment guide is configured to be cut through during a resection of the bone. 18. An orthopedic system comprising: a patient-specific alignment guide operable for preparing a bone of a patient during joint arthroplasty, the alignment guide including a patient-specific bone engagement surface configured to be complementary to a surface of the bone of the patient, the alignment guide including a plurality of guiding bores; a plurality of alignment members receivable through corresponding guiding bores for attaching the alignment guide to the bone; a cutting block mountable to one or more of the plurality of alignment members and configured to guide a first resection of the bone by cutting through the alignment guide; and one or more pins, wherein a one of the plurality of alignment members or the one or more pins are cannulated and configured to receive the other of the plurality of alignment members or the one or more pins to mount the cutting block into a desired position relative to the bone. 19. The system of claim 18, the cutting block comprises at least one of a distal cutting block mountable to at least a first of the plurality of alignment members and a 4-in-1 cut guide mountable to at least a second of the plurality of alignment members.