[특허]Piston assembly and related systems for use with a fluidics device

SciKon Innovation, Inc.

검색어에 아래의 연산자를 사용하시면 더 정확한 검색결과를 얻을 수 있습니다.
검색연산자

검색도움말
검색연산자	기능	검색시 예
()	우선순위가 가장 높은 연산자	예1) (나노 (기계 \| machine))
공백	두 개의 검색어(식)을 모두 포함하고 있는 문서 검색	예1) (나노 기계) 예2) 나노 장영실
\|	두 개의 검색어(식) 중 하나 이상 포함하고 있는 문서 검색	예1) (줄기세포 \| 면역) 예2) 줄기세포 \| 장영실
!	NOT 이후에 있는 검색어가 포함된 문서는 제외	예1) (황금 !백금) 예2) !image
*	검색어의 *란에 0개 이상의 임의의 문자가 포함된 문서 검색	예) semi*
""	따옴표 내의 구문과 완전히 일치하는 문서만 검색	예) "Transform and Quantization"

과학기술 지식인프라 ScienceON

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

특허 상세정보

MyON담기

내보내기 페이스북 공유 트위터 공유 카카오톡 공유

Piston assembly and related systems for use with a fluidics device

특허상세정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	B01L-003/00 C12M-001/26 F04B-053/00 F04B-023/02 F04B-053/14 F04B-001/00 F04B-013/00 B01L-003/02
출원번호	US-0954546 (2015-11-30)
등록번호	US-10035145 (2018-07-31)
발명자 / 주소	McClelland, Randall Edwin Bunger, Maureen Kay Ziberna, Frank Jay
출원인 / 주소	SciKon Innovation, Inc.
대리인 / 주소	Forrest Firm, P.C.
인용정보	피인용 횟수 : 0 인용 특허 : 45

초록
▼

Disclosed are fluidics devices and assemblies allowing for fluid flow between a plurality of wells. The fluidics devices and assemblies that are provided mimic in vivo tissue environments by allowing for initially segregated tissue cultures that can then be linked through fluid flow to measure integrated tissue response. The fluidics devices and assemblies provide a pumpless system using surface tension, gravity, and channel geometries. By linking human tissue functional systems to better simulate in vivo feedback and response signals between the tissues...

대표
청구항
▼

1. A piston assembly comprising: a reservoir tray configured for nesting engagement with a fluidics device and including: a liquid chamber defining a chamber floor for containing a dosing fluid;an aperture defined in the chamber floor and positioned above a dosing well of the fluidics device when the reservoir tray is nestably engaged with the fluidics device;wherein the chamber floor is angled and the aperture is defined at a lower portion of the chamber floor such that the dosing fluid flows through the aperture into the dosing well of the fluidics device when the reservoir tray and the fluidics device are nestably engaged;a reservoir cover defining a piston chamber that receives at least a portion of a piston for allowing the piston to translate between a first position a distance from the aperture and a second position proximal to the aperture; anda crank engaged with the piston for translating the piston between the first position and the second position such that the translation from the first position to the second position results in a portion of the dosing fluid flowing through the aperture to the dosing well when the reservoir tray and the fluidics device are nestably engaged. 2. The piston assembly of claim 1, wherein the aperture defines one or more openings, the one or more openings configured for communication with the dosing fluid in the liquid chamber such that surface tension of the dosing fluid maintains the dosing fluid in the liquid chamber until the piston is translated from the first position to the second position. 3. The piston assembly of claim 1, wherein the piston chamber defines a chamber lip for engaging with a piston catch defined by the piston, thereby retarding the translation of the piston when the piston translates from the second position to the first position. 4. The piston assembly of claim 1, wherein the reservoir cover defines a cover lip for engaging with a crank catch defined by the crank, thereby retarding the translation of the crank when the piston is translating from the second position to the first position. 5. The piston assembly of claim 1, wherein the chamber floor further defines a piston well including the aperture for receiving the piston in the second position and the dosing fluid. 6. The piston assembly of claim 5, wherein the piston well further includes a piston well wall for nestably engaging at least half of the circumference of the piston during the entire translation between the first position and the second position and for delivering the dosing fluid to the piston well. 7. The piston assembly of claim 6, wherein the chamber floor further defines a floor recess at the lower portion of the chamber floor proximal to the piston well and the piston well wall for receiving the dosing fluid and delivering the dosing fluid to the piston well. 8. The piston assembly of claim 1, wherein the crank includes a pin engaged within a piston channel defined in the piston for engaging the crank to the piston. 9. The piston assembly of claim 7, wherein the crank is in communication with a solenoid. 10. The piston assembly of claim 1, further comprising a fluidics device including: a dosing well positioned upstream from a plurality of wells for containing a respective host fluid; andone or more channels extending between adjacent upstream and downstream wells to define a channel fluid flow path there between such that a dosing fluid deposited into the dosing well flows to the respective host fluid of the adjacent downstream well along the channel fluid flow path there between, and the respective host fluid subsequently flows to each adjacent downstream well along the channel fluid flow path there between. 11. The piston assembly of claim 10, wherein the fluidics device further includes: a collection well downstream from the plurality of wells to collect the respective host fluid after its having flowed through the plurality of wells, wherein the collection well defines an aperture; anda second reservoir tray comprising at least one chamber for containing a respective chamber fluid and configured for nesting engagement underneath the fluidics device such that fluid from the collection well of the fluidics device flows through the aperture into the chamber of the second reservoir tray when the second reservoir tray and the fluidics device are nestably engaged. 12. The piston assembly of claim 10, further comprising: a second fluidics device configured for nesting engagement underneath the fluidics device;the fluidics device further including a collection well downstream from the plurality of wells to collect the respective host fluid after its having flowed through the plurality of wells;wherein the collection well defines an aperture such that fluid from the collection well flows through the aperture into the dosing well of the second fluidics device when the fluidics devices are nestably engaged. 13. The piston assembly of claim 12, further comprising: one or more additional fluidics devices configured for nesting engagement underneath the second fluidics device;wherein the additional fluidics devices each comprise a collection well downstream from the plurality of wells to collect the respective host fluid after its having flowed through the plurality of wells;wherein the collection well of each fluidics device defines an aperture such that fluid from the collection well flows through the aperture into the dosing well of the additional fluidics device positioned underneath when the fluidics devices are nestably engaged. 14. A piston assembly comprising: a reservoir tray configured for nesting engagement with a fluidics device and including a liquid chamber defining a chamber floor and dividing walls creating subchambers for housing a dosing fluid, each of the subchambers having: an aperture defined in the chamber floor and positioned above a dosing well of the fluidics device when the reservoir tray is nestably engaged with the fluidics device;wherein the chamber floor is angled and the aperture is defined at a lower portion of the chamber floor such that the dosing fluid flows through the aperture into the dosing well of the fluidics device when the reservoir tray and the fluidics device are nestably engaged;a reservoir cover defining a piston chamber housing a piston for each of the subchambers for allowing the piston to translate a between a first position a distance from the aperture and a second position proximal to the aperture; anda crank assembly engaged with the pistons for translating the pistons such that a portion of the dosing fluid flows through the aperture when the reservoir tray and the fluidics device are nestably engaged. 15. The piston assembly of claim 14, wherein the aperture defines one or more openings, the one or more openings configured for communication with the dosing fluid in the liquid chamber such that surface tension of the dosing fluid maintains the dosing fluid in the liquid chamber until the piston is translated from the first position to the second position. 16. The piston assembly of claim 14, wherein the piston chamber defines a chamber lip for engaging with a piston catch defined by the piston, thereby retarding the translation of the piston when the piston translates from the second position to the first position. 17. The piston assembly of claim 14, wherein the reservoir cover defines a cover lip for engaging with a crank catch defined by the crank assembly, thereby retarding the translation of the crank when the piston is translating from the second position to the first position. 18. The piston assembly of claim 14, wherein the chamber floor further defines a piston well including the aperture for receiving the piston in the second position and the dosing fluid. 19. The piston assembly of claim 18, wherein the piston well further includes a piston well wall for nestably engaging at least half of the circumference of the piston during the entire translation between the first position and the second position and for delivering the dosing fluid to the piston well. 20. The piston assembly of claim 18, wherein the chamber floor further defines a floor recess at the lower portion of the chamber floor proximal to the piston well and the piston well wall for receiving the dosing fluid and delivering the dosing fluid to the piston well. 21. The piston assembly of claim 14, wherein the crank assembly includes cranks, each crank engaged with the piston of each of the subchambers for translating the piston between the first position and the second position. 22. The piston assembly of claim 21, wherein each crank is in communication with a solenoid including a pin engaged with a piston channel defined by each piston. 23. The piston assembly of claim 14, wherein each piston defines a piston head and wherein the crank assembly includes a piston bar engaged with all of the piston heads for translating the pistons simultaneously between the first position and the second position. 24. The piston assembly of claim 23, wherein the crank assembly further includes at least one crank engaged with the piston bar for translating the piston bar, thereby translating the pistons between the first position and the second position. 25. The piston assembly of claim 24, wherein the at least one crank is in communication with at least one solenoid including a pin engaged with a piston bar channel defined by the piston bar. 26. The piston assembly of claim 14, further comprising a fluidics device including: one or more dosing wells positioned upstream from a plurality of wells for containing a respective host fluid; andone or more channels extending between adjacent upstream and downstream wells to define a channel fluid flow path there between such that a dosing fluid deposited into the dosing well flows to the respective host fluid of the adjacent downstream well along the channel fluid flow path there between, and the respective host fluid subsequently flows to each adjacent downstream well along the channel fluid flow path there between.

이 특허에 인용된 특허 (45)

IPC 상위 출원인

내보내기

상세정보
내보내기 구분	파일저장 인쇄 메일전송
구성항목	관리번호, 국가코드, 자료구분, 상태, 출원번호, 출원일자, 공개번호, 공개일자, 등록번호, 등록일자, 발명명칭(한글), 발명명칭(영문), 출원인(한글), 출원인(영문), 출원인코드, 대표IPC 관리번호, 국가코드, 자료구분, 상태, 출원번호, 출원일자, 공개번호, 공개일자, 공고번호, 공고일자, 등록번호, 등록일자, 발명명칭(한글), 발명명칭(영문), 출원인(한글), 출원인(영문), 출원인코드, 대표출원인, 출원인국적, 출원인주소, 발명자, 발명자E, 발명자코드, 발명자주소, 발명자 우편번호, 발명자국적, 대표IPC, IPC코드, 요약, 미국특허분류, 대리인주소, 대리인코드, 대리인(한글), 대리인(영문), 국제공개일자, 국제공개번호, 국제출원일자, 국제출원번호, 우선권, 우선권주장일, 우선권국가, 우선권출원번호, 원출원일자, 원출원번호, 지정국, Citing Patents, Cited Patents
저장형식	Text(ASCII format) Excel format PIAS분석(.xls)
메일정보	받는사람 (필수) @ 보내는사람 (선택) @ 제목 내용 KISTI 검색결과 이메일 서비스
안내	> 총 건의 자료가 검색되었습니다. > 다운받으실 자료의 인덱스를 입력하세요. (1-10,000) > 검색결과의 순서대로 최대 10,000건 까지 다운로드가 가능합니다. > 데이타가 많을 경우 속도가 느려질 수 있습니다.(최대 2~3분 소요) > 다운로드 파일은 UTF-8 형태로 저장됩니다. 파일의 내용이 제대로 보이지 않을실 때는 웹브라우저 상단의 보기 -> 인코딩 -> 자동선택 여부를 확인하십시오 > ~ > Text(ASCII format) Excel format

과학기술 지식인프라 ScienceON

ScienceON Chatbot

연합인증

특허 상세정보

Piston assembly and related systems for use with a fluidics device

초록
▼

대표
청구항
▼

이 특허에 인용된 특허 (45)

IPC 상위 출원인

과제정보

상세정보조회

원문조회

IPC 상세정보(version : 201201)

연구과제 성과물(0)

참여연구원의 다른 문헌(0)

처리중입니다.

잠시만 기다려주세요.

ScienceON Chatbot

연합인증

특허 상세정보

Piston assembly and related systems for use with a fluidics device

초록 ▼

대표청구항 ▼

이 특허에 인용된 특허 (45)

IPC 상위 출원인

과제정보

상세정보조회

원문조회

IPC 상세정보(version : 201201)

연구과제 성과물(0)

참여연구원의 다른 문헌(0)

처리중입니다.

잠시만 기다려주세요.

초록
▼

대표
청구항
▼