Multiple dose delivery device with manually depressible actuator and one-way valve for storing and dispensing substances, and related method
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
B65D-037/00
B65D-083/00
B65D-047/18
A61F-009/00
B05B-011/00
B05B-015/50
출원번호
US-0419352
(2012-03-13)
등록번호
US-10040619
(2018-08-07)
발명자
/ 주소
Py, Daniel
Adamo, Benoit
출원인 / 주소
MEDINSTILL DEVELOPMENT LLC
대리인 / 주소
McCarter & English, LLP
인용정보
피인용 횟수 :
0인용 특허 :
62
초록▼
A dispenser has a body with a variable-volume storage chamber for storing substance, and a dispensing portion defining a dosage chamber in fluid communication with the storage chamber. A first valve includes a valve seat and a flexible valve cover seated thereon defining a normally-closed fluid-tigh
A dispenser has a body with a variable-volume storage chamber for storing substance, and a dispensing portion defining a dosage chamber in fluid communication with the storage chamber. A first valve includes a valve seat and a flexible valve cover seated thereon defining a normally-closed fluid-tight seam therebetween. The valve cover relative to moves from the valve seat to allow substance through the seam and out of the dispenser. A second valve allows substance from the storage chamber into the dosage chamber and substantially prevents flow from the dosage chamber into the storage chamber. An actuator is manually movable between (i) a first non-actuated position, and (ii) a second actuated position extending into the dosage chamber for compressing a dose of substance therein, dispensing substance through the first valve. The elasticity of the actuator causes it to return to the first non-actuated position upon manually releasing the actuator.
대표청구항▼
1. A method comprising the following steps: filling a sealed, empty device including a body, a slidable stopper slidingly received within the body of the sealed, empty device and defining a variable-volume storage chamber therein, and a one-way valve, the filling step including: slidably receiving t
1. A method comprising the following steps: filling a sealed, empty device including a body, a slidable stopper slidingly received within the body of the sealed, empty device and defining a variable-volume storage chamber therein, and a one-way valve, the filling step including: slidably receiving the stopper within the body;after the receiving step, fixing the slidable stopper relative to the body with the stopper located in a first position within the body such that the slidable stopper cannot move from the first position;engaging an exterior back surface of the slidable stopper with a collar of a filling apparatus that includes: (i) said collar and (ii) a filling member;penetrating the stopper with the filling member with the stopper fixed relative to the body and located in the first position such that the slidable stopper does not move from the first position during penetration;introducing a fluid into the variable-volume storage chamber through the filling member;withdrawing the filling member; andsealing an aperture in the slidable stopper to seal the variable-volume storage chamber. 2. A method as defined in claim 1, further comprising the step of sterilizing the sealed empty device prior to the filling step. 3. A method as defined in claim 1, further comprising the step of drawing a vacuum through one or more of the filling member or a filling aperture during the filling step. 4. A method as defined in claim 3, further comprising drawing with the vacuum fluid out of the variable-volume storage chamber and into one or more of a filling member conduit or a collection container during the filling step, to thereby leave substantially zero air within the chamber after the withdrawing step. 5. A method as defined in claim 1, further comprising the step of providing an overpressure of sterile air over one or more of the filling member or the device during the filling step. 6. A method as defined in claim 1, wherein the sealing step comprises applying radiation or energy to the slidable stopper. 7. A method as defined in claim 6, wherein the radiation or energy comprises one or more of laser radiation or thermal energy. 8. A method as defined in claim 1, wherein the device further includes a dosage chamber connectable in fluid communication between the one-way valve and the variable-volume storage chamber, and an actuator movable between a non-actuated position and an actuated position for compressing a dose of fluid within the dosage chamber and dispensing the dose through the one-way valve. 9. A method as defined in claim 1, further comprising the step of moving the slidable stopper further within the body from the first position after the filling step and prior to dispensing fluid from the device. 10. A method comprising the following steps: filling a sealed, empty device including a body, a slidable stopper slidingly received within the body and defining a variable-volume storage chamber therein, and a one-way valve, the filling step including the following steps (a) through (e) performed in sequence: (a) penetrating the slidable stopper with a filling member and the stopper located in a first position within the body;(b) moving the slidable stopper to a second position within the body during or after penetrating the slidable stopper with the filling member;(c) introducing a fluid into the variable-volume storage chamber through the filling member after said moving step;(d) withdrawing the filling member; and(e) sealing an aperture in the slidable stopper to seal the variable-volume storage chamber. 11. A method as defined in claim 10, further comprising moving the slidable stopper from the first position to further within the body after the filling step and prior to dispensing fluid from the device. 12. A method as defined in claim 10, further comprising the step of moving the filling member and the slidable stopper from the second position back to the first position while introducing the fluid into the variable-volume storage chamber. 13. A method as defined in claim 10, further comprising the step of sterilizing the sealed empty device prior to the filling step. 14. A method as defined in claim 10, further comprising the step of drawing a vacuum through one or more of the filling member or a filling aperture during the filling step. 15. A method as defined in claim 14, further comprising drawing with the vacuum fluid out of the variable-volume storage chamber and into one or more of a filling member conduit or a collection container during the filling step, to thereby leave substantially zero air within the chamber after the withdrawing step. 16. A method as defined in claim 10, further comprising the step of providing an overpressure of sterile air over one or more of the filling member or the device during the filling step. 17. A method as defined in claim 10, wherein the sealing step comprises applying radiation or energy to the slidable stopper. 18. A method as defined in claim 17, wherein the radiation or energy comprises one or more of laser radiation or thermal energy. 19. A method as defined in claim 10, wherein the device further includes a dosage chamber connectable in fluid communication between the one-way valve and the variable-volume storage chamber, and an actuator movable between a non-actuated position and an actuated position for compressing a dose of fluid within the dosage chamber and dispensing the dose through the one-way valve. 20. A method comprising: filling a sealed, empty device including a body, a slidable stopper slidingly received within the body and defining a variable-volume storage chamber therein, and a one-way valve, the filling step including the following steps (a) through (e) performed in sequence: (a) penetrating the slidable stopper with a filling member and the stopper located in a first position within the body;(b) moving the slidable stopper to a second position within the body during or after penetrating the slidable stopper with the filling member, wherein the moving step further comprises moving the filling member to the second position within the body during or after penetrating the slidable stopper with the filling member;(c) introducing a fluid into the variable-volume storage chamber through the filling member after said moving step, wherein, during the introducing step, the slidable stopper moves toward the first position and the filling member remains substantially in the second position;(d) withdrawing the filling member; and(e) sealing an aperture in the slidable stopper to seal the variable-volume storage chamber.
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