최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
DataON 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Edison 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0400978 (2017-01-07) |
등록번호 | US-10046100 (2018-08-14) |
발명자 / 주소 |
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출원인 / 주소 |
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대리인 / 주소 |
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인용정보 | 피인용 횟수 : 0 인용 특허 : 290 |
An automated peritoneal dialysis system provides various features including prescription-driven dialysis fluid preparation, an integrated disposable fluid circuit, and sensor capabilities that allow accurate filing and draining control with high safety margins. Features include a peritoneal fluid ci
An automated peritoneal dialysis system provides various features including prescription-driven dialysis fluid preparation, an integrated disposable fluid circuit, and sensor capabilities that allow accurate filing and draining control with high safety margins. Features include a peritoneal fluid circuit with a pressure sensor at either end and methods and devices for using the pressure signals. Other features and embodiments are disclosed.
1. A peritoneal dialysis disposable unit, comprising: a manifold unit with a first and a second array of ports and containing a mechanism for selectively interconnecting the first array of ports with the second array of ports to define respective fluid paths, the interconnecting being completed thro
1. A peritoneal dialysis disposable unit, comprising: a manifold unit with a first and a second array of ports and containing a mechanism for selectively interconnecting the first array of ports with the second array of ports to define respective fluid paths, the interconnecting being completed through a pumping portion;a water inlet port of the first array of ports of the manifold unit being fluidly connected to a source of purified water through a water inlet tube;a respective port of the first array of ports of the manifold unit being connected to a first container holding at least a sterile, concentrated osmotic agent;one port of each of the first and second arrays of ports being connected to respective ports of an empty sterile mixing container, the empty sterile mixing container having a capacity sufficient for at least a single automated peritoneal dialysis treatment cycle; andat least a port of the second array of ports of the manifold unit being connected to a tubing set that includes a pre-attached peritoneal fill/drain line. 2. The unit of claim 1, wherein said first container contains a mixture of a sterile osmotic agent and electrolytes in a predefined concentration ratio effective to permit a concentration of said osmotic agent to be determined whereby the electrolytes function as a marker to establish a conductivity versus concentration characteristic that is monotonic within a range of concentrations suitable for closed-loop control. 3. The unit of claim 2, wherein a fluid path that connects to the source of purified water includes an inline sterilizing filter. 4. The unit of claim 2, further comprising: a first removable seal closing the water inlet tube connected to the water inlet port;a second removable seal closing the pre-attached peritoneal fill/drain line; anda third removable seal closing a waste drain line fluidly connected to at least one of the first and second arrays of ports, whereinsaid peritoneal dialysis disposable unit is a closed, sterile system, which is accessible to the outside environment only when at least one of said first, second, and third removable seals is opened. 5. The unit of claim 4, further comprising an air line connecting a pressure pod on the peritoneal fill/drain line with a pressure transducer. 6. The unit of claim 4, wherein the pumping portion includes a pumping tube segment. 7. The unit of claim 2, further comprising an air line connecting a pressure pod on the peritoneal fill/drain line with a pressure transducer. 8. The unit of claim 2, wherein the pumping portion includes a pumping tube segment. 9. The unit of claim 2, wherein the pumping portion includes only one pumping tube segment. 10. The unit of claim 1, wherein a fluid path that connects to the source of purified water includes an inline sterilizing filter. 11. The unit of claim 10, further comprising: a first removable seal closing the water inlet tube connected to the water inlet port;a second removable seal closing the pre-attached peritoneal fill/drain line; anda third removable seal closing a waste drain line fluidly connected to at least one of the first and second arrays of ports, whereinsaid peritoneal dialysis disposable unit is a closed, sterile system, which is accessible to the outside environment only when at least one of said first, second, and third removable seals is opened. 12. The unit of claim 10, further comprising an air line connecting a pressure pod on the peritoneal fill/drain line with a pressure transducer. 13. The unit of claim 10, wherein the pumping portion includes a pumping tube segment. 14. The unit of claim 10, wherein the pumping portion includes only one pumping tube segment. 15. The unit of claim 1, further comprising: a first removable seal closing the water inlet tube connected to the water inlet port;a second removable seal closing the pre-attached peritoneal fill/drain line; anda third removable seal closing a waste drain line fluidly connected to at least one of the first and second arrays of ports, whereinsaid peritoneal dialysis disposable unit is a closed, sterile system, which is accessible to the outside environment only when at least one of said first, second, and third removable seals is opened. 16. The unit of claim 15, wherein the pumping portion includes only one pumping tube segment. 17. The unit of claim 1, further comprising an air line connecting a pressure pod on the peritoneal fill/drain line with a pressure transducer. 18. The unit of claim 17, wherein the pumping portion includes a pumping tube segment. 19. The unit of claim 1, wherein the pumping portion includes a pumping tube segment. 20. The unit of claim 19, wherein the pumping portion includes only one pumping tube segment. 21. The unit of claim 1, wherein the pumping portion includes only one pumping tube segment. 22. A peritoneal dialysis system, comprising: a peritoneal dialysis disposable unit, including a manifold unit with a first and a second array of ports and containing a mechanism for selectively interconnecting the first array of ports with the second array of ports to define respective flow paths, the interconnecting being completed through a pumping portion,a water inlet port of the first array of ports of the manifold unit being fluidly connected to a source of purified water through a water inlet tube;a respective port of the first array of ports of the manifold unit being connected to a first container holding at least a sterile, concentrated osmotic agent;one port of each of the first and second arrays of ports being connected to respective ports of an empty sterile mixing container, the empty sterile mixing container having a capacity sufficient for at least a single automated peritoneal dialysis treatment cycle; andat least a port of the second array of ports of the manifold unit being connected to a tubing set that includes a pre-attached peritoneal fill/drain line; anda controller configured to control an actuator mechanism adapted to flow fluid through the disposable unit, the controller being programmed to calculate respective flow characteristics of respective flow paths connecting the mixing container to the source of purified water, the first container, and an electrolyte container at a first time and later use the calculated flow characteristics to control quantities of fluid flowed from the source of purified water, the first container, and the electrolyte container to the mixing container. 23. The peritoneal dialysis system according to claim 22, wherein said first container contains a mixture of a sterile osmotic agent and electrolytes in a predefined concentration ratio effective to permit a concentration of said osmotic agent to be determined whereby the electrolytes function as a marker to establish a conductivity versus concentration characteristic that is monotonic within a range of concentrations suitable for closed-loop control. 24. The peritoneal dialysis system according to claim 22, wherein a fluid path that connects to the source of purified water includes an inline sterilizing filter. 25. The peritoneal dialysis system according to claim 22, wherein the disposable unit further comprises: a first removable seal closing the water inlet tube connected to the water inlet port;a second removable seal closing the pre-attached peritoneal fill/drain line; anda third removable seal closing a waste drain line fluidly connected to at least one of the first and second arrays of ports, whereinsaid peritoneal dialysis disposable unit is a closed, sterile system, which is accessible to the outside environment only when at least one of said first, second, and third removable seals is opened. 26. The peritoneal dialysis system according to claim 22, wherein the disposable unit further comprises: an air line connecting a pressure pod on the peritoneal fill/drain line with a pressure transducer. 27. The peritoneal dialysis system according to claim 22, wherein the pumping portion includes only one pumping tube segment. 28. The peritoneal dialysis system of claim 22, further comprising: one or more flow rate sensors configured to measure a flow rate through at least one flow path of the respective flow paths,wherein the controller is programmed to calculate the respective flow characteristics of the respective flow paths by commanding the actuator mechanism to flow fluid through said disposable unit and recording sensor signals from the one or more flow rate sensors indicating flow rates of said fluid through the at least one flow path. 29. The peritoneal dialysis system of claim 28, wherein the controller is further programmed to detect connection of said disposable unit to the source of purified water and to calculate said respective flow characteristic responsively to a detection of the connection of said disposable unit. 30. The peritoneal dialysis system of claim 28, wherein the one or more flow rate sensors include a flow sensor connected to a pump outlet, andthe controller is programmed to calculate said respective flow characteristics by pumping fluid while simultaneously measuring flow rate using the flow sensor. 31. The peritoneal dialysis system of claim 22, wherein the controller is further programmed to detect connection of said disposable unit to the source of purified water and to calculate said respective flow characteristic responsively to a detection of the connection of said disposable unit to the source of purified water. 32. The peritoneal dialysis system of claim 31, wherein the controller is programmed to calculate said respective flow characteristics by pumping fluid while simultaneously measuring flow rate using a flow sensor connected to a pump outlet. 33. The peritoneal dialysis system of claim 22, wherein the controller is programmed to calculate said respective flow characteristics by pumping fluid while simultaneously measuring flow rate using a flow sensor connected to a pump outlet.
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