System and method for supporting sub-physiologic and physiologic tidal volumes in spontaneous or non-spontaneous breathing during high frequency ventilation
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61M-016/00
A61M-016/20
A61M-016/12
출원번호
US-0515458
(2010-12-01)
등록번호
US-10058664
(2018-08-28)
국제출원번호
PCT/IB2010/055537
(2010-12-01)
§371/§102 date
20120612
(20120612)
국제공개번호
WO2011/073839
(2011-06-23)
발명자
/ 주소
Kimm, Gardner
Garde, Smita
Arcilla, Mabini
출원인 / 주소
KONINKLIJKE PHILIPS N.V.
인용정보
피인용 횟수 :
0인용 특허 :
24
초록▼
A device for providing a high frequency ventilation to a patient that includes a pressure generating system that delivers a flow of breathing gas to the patient, where the flow has a first and second positive pressure levels that alternate with one another in a plurality of cycles in the flow so as
A device for providing a high frequency ventilation to a patient that includes a pressure generating system that delivers a flow of breathing gas to the patient, where the flow has a first and second positive pressure levels that alternate with one another in a plurality of cycles in the flow so as to have a frequency and an amplitude. The flow generates a mean airway pressure. A controller, coupled to the pressure generating system, is configured to make a determination, as to a spontaneous breathing, or an attempt, by the patient, or a change in a user settings by a user, and in response adjusts the mean airway pressure, modulates the frequency and a duty cycle of the flow, or modulates a level of the flow and the amplitude of the flow, or two or more flows.
대표청구항▼
1. A method of providing high frequency positive pressure ventilation (HFPPV) to a patient, comprising acts of: delivering a flow of breathing gas to the patient, the flow of breathing gas having a first positive pressure level and a second positive pressure level, the first and second positive pres
1. A method of providing high frequency positive pressure ventilation (HFPPV) to a patient, comprising acts of: delivering a flow of breathing gas to the patient, the flow of breathing gas having a first positive pressure level and a second positive pressure level, the first and second positive pressure levels alternating with one another in a plurality of cycles in the flow of breathing gas to have a frequency and an amplitude, the flow of breathing gas to the patient generating a mean airway pressure and having a flow amplitude;performing by a controller a determination of spontaneous breathing efforts by the patient, wherein the spontaneous breathing efforts comprise one of a spontaneous breathing, an attempt at spontaneous breathing and non-spontaneous breathing;performing by the controller a simultaneous control of: an adjustment of the mean airway pressure, a modulation of the frequency and a duty cycle of the flow of breathing gas, and a modulation of the flow amplitude of the flow of breathing gas, to implement an HFPPV mode with an extended range for the frequency, the duty cycle, a flow level, and the mean airway pressure of positive pressure ventilation including 2 Hz and 25 Hz based on the simultaneous control; andproviding by the controller physiologic volumes interspersed with high frequency sub-physiologic volumes by intermittently modulating the mean airway pressure,wherein the mean airway pressure is modulated by intermittently varying an exhalation resistance,wherein the simultaneous control and the implementing of the HFPPV mode is in response to the determination, andwherein the HFPPV mode is implemented by delivering the modulated flow of breathing gas via a pressure generating system through a patient circuit, in accordance with the adjusted mean airway pressure, and the modulated frequency and duty cycle. 2. The method of claim 1, wherein the mean airway pressure of the patient is controlled by adjusting an active exhalation valve. 3. The method of claim 2, wherein the active exhalation valve, the frequency and an inspiratory time of the flow of breathing gas, and the flow level of the breathing gas are controlled proportionally to a spontaneous breathing pattern. 4. The method of claim 2, wherein the active exhalation valve, the frequency and the duty cycle of the flow of breathing gas, and the flow level of the breathing gas are controlled in a bi-level manner for inhalation and exhalation phases of a spontaneous breathing pattern of the spontaneous breathing efforts. 5. The method of claim 2, wherein the active exhalation valve, the frequency and the duty cycle of the flow of breathing gas, and the flow level of the breathing gas are controlled in a manner as determined by user settings for high frequency ventilation (HFV) and a user intervention. 6. A high frequency positive pressure ventilation (HFPPV) support system, comprising: a pressure generating system;a patient circuit operatively coupled to the pressure generating system and adapted to be coupled to a patient; anda controller operatively coupled to the pressure generating system, the controller being configured to: control the pressure generating system to deliver a flow of breathing gas to the patient through the patient circuit, the flow of breathing gas having a first positive pressure level and a second positive pressure level, the first and second positive pressure levels alternating with one another in a plurality of cycles in the flow of breathing gas to have a frequency and an amplitude, the flow of breathing gas having a mean airway pressure and a flow amplitude;perform a determination of spontaneous breathing efforts by the patient;wherein the spontaneous breathing efforts comprise one of a spontaneous breathing, an attempt at spontaneous breathing and non-spontaneous breathing,the controller being further configured to: perform a simultaneous control of: an adjustment of the mean airway pressure, a modulation of the frequency and a duty cycle of the flow of breathing gas, and a modulation of the flow amplitude of the flow of breathing gas;implement an HFPPV mode with an extended range for the frequency, the duty cycle, a flow level of breathing gas, and the mean airway pressure of a positive pressure ventilation including 2 Hz and 25 Hz based on the simultaneous control; andprovide physiologic volumes interspersed with high frequency sub-physiologic volumes by intermittently modulating the mean airway pressure,wherein the mean airway pressure is modulated by intermittently varying an exhalation resistance,wherein the simultaneous control and the implementing of the HFPPV mode is in response to the determination. 7. The pressure support system of claim 6, wherein the mean airway pressure is controlled by adjusting an active exhalation valve. 8. The pressure support system of claim 7, wherein the active exhalation valve, the frequency and the duty cycle of the flow of breathing gas, and the flow level of the breathing gas are controlled proportionally to a spontaneous breathing pattern of the spontaneous breathing efforts. 9. The pressure support system of claim 7, wherein the active exhalation valve, the frequency and the duty cycle of the flow of breathing gas, and the flow level of the breathing gas are controlled in a bi-level manner for an inhalation and an exhalation phases of a spontaneous breathing pattern of the spontaneous breathing efforts. 10. The pressure support system of claim 7, wherein the active exhalation valve, the frequency and the duty cycle of the flow of breathing gas, and the flow level of the breathing gas are controlled in a bi-level manner as determined by user settings for high frequency ventilation and a user intervention. 11. The pressure support system of claim 6, wherein the controller is further configured to provide physiologic volumes interspersed with high frequency sub-physiologic volumes by intermittently modulating the mean airway pressure, wherein the mean airway pressure is modulated by intermittently varying the flow amplitude of the flow of breathing gas. 12. The pressure support system of claim 6, wherein the controller is further configured to provide providing physiologic volumes interspersed with high frequency sub-physiologic volumes by intermittently modulating the mean airway pressure, wherein the mean airway pressure is modulated by intermittently varying the frequency. 13. The pressure support system of claim 6, wherein the controller is further configured to provide physiologic volumes interspersed with high frequency sub-physiologic volumes by intermittently modulating the mean airway pressure, wherein the mean airway pressure is modulated by intermittently varying the duty cycle. 14. The pressure support system of claim 6, wherein the mean airway pressure is modulated by intermittently varying one of the exhalation resistance, the amplitude, the frequency, the duty cycle, and combinations thereof. 15. The pressure support system of claim 6, wherein the controller is further configured to provide physiologic volumes interspersed with high frequency sub-physiologic volumes by intermittently modulating the mean airway pressure, wherein modulating the mean airway pressure is configured to achieve physiologic volumes to provide for the spontaneous breathing. 16. The pressure support system of claim 6, wherein the controller is further configured to provide physiologic volumes interspersed with high frequency sub-physiologic volumes by intermittently modulating the mean airway pressure, wherein modulating the mean airway pressure is configured to achieve one selected from the group consisting of physiologic volumes to provide for the spontaneous breathing with a pressure support and physiologic volumes in an absence of the spontaneous breathing. 17. A high frequency support system, comprising: a pressure generating system;a patient circuit operatively coupled to the pressure generating system and configured for being coupled to a patient; anda controller operatively coupled to the pressure generating system, the controller being configured to: control the pressure generating system to deliver a flow of breathing gas to the patient through the patient circuit, the flow of breathing gas having a first positive pressure level and a second positive pressure level, the first and second positive pressure levels alternating with one another in a plurality of cycles in the flow of breathing gas to have a frequency and an amplitude, the flow of breathing gas having a mean airway pressure and a flow amplitude;perform a determination of spontaneous breathing efforts by the patient;wherein the spontaneous breathing efforts comprise one of a spontaneous breathing, an attempt at spontaneous breathing and non-spontaneous breathing,the controller being further configured to: simultaneously control an adjustment of the mean airway pressure, a modulation of the frequency and a duty cycle of the flow of breathing gas, and a modulation of the flow amplitude of the flow of breathing gas;implement an HFPPV mode with an extended range for the frequency, the duty cycle, a flow level of breathing gas, and the mean airway pressure of a positive pressure ventilation including 2 Hz and 25 Hz based on the simultaneous control;provide physiologic volumes interspersed with high frequency sub-physiologic volumes by intermittently modulating the mean airway pressure; andprovide physiologic volumes interspersed with high frequency sub-physiologic volumes by intermittently modulating the mean airway pressure,wherein the mean airway pressure is modulated by intermittently varying an exhalation resistance, andwherein the simultaneous control and the implementing of the HFPPV mode is in response to the determination.
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이 특허에 인용된 특허 (24)
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Tom Leenhoven NL, Device and method for using oscillatory pressure ratio as an indicator for lung opening during high frequency oscillatory ventilation.
Winter Dean C. (San Antonio TX) Harris Ralph E. (Cary NC) Honeyager Kevin S. (San Antonio TX), High frequency oscillatory ventilator and respiratory measurement system.
Reese David M. (c/o Spectramed Inc. ; 805 Liberty La. Dayton OH 45449) Rauterkus L. Thomas (c/o Spectramed Inc. ; 805 Liberty La. Dayton OH 45449) Jensen Robert L. (4719 Broom St. San Antonio TX 7821, High frequency ventilation method.
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