The present invention relates to a carrier for the delivery of a nutraceutical or cosmeceutical active comprising non-neutralized tocopheryl phosphate and a hydrophobic vehicle. The present invention also relates to a formulation comprising the carrier and a nutraceutical or cosmeceutical active.
대표청구항▼
1. A carrier for the delivery of a nutraceutical or cosmeceutical active comprising non-neutralised tocopheryl phosphate and a hydrophobic vehicle, wherein the non-neutralised tocopheryl phosphate comprises a mixture of mono-(tocopheryl) phosphate and di-(tocopheryl) phosphate, and wherein the pH of
1. A carrier for the delivery of a nutraceutical or cosmeceutical active comprising non-neutralised tocopheryl phosphate and a hydrophobic vehicle, wherein the non-neutralised tocopheryl phosphate comprises a mixture of mono-(tocopheryl) phosphate and di-(tocopheryl) phosphate, and wherein the pH of the non-neutralised tocopheryl phosphate is in a range of about 2 to about 4, and wherein the carrier comprises the hydrophobic vehicle in an amount of at least about 80.0% w/w of the total concentration of the carrier. 2. The carrier of claim 1, wherein the pH of the non-neutralised tocopheryl phosphate is about 2 or 3. 3. The carrier of claim 1, wherein the mixture of mono-(tocopheryl) phosphate and di-(tocopheryl) phosphate comprises: (a) a compound selected from the group consisting of mono-(tocopheryl) phosphate, mono-(tocopheryl) phosphate monosodium salt, mono-(tocopheryl) phosphate disodium salt, and a mixture thereof; and (b) a compound selected from the group consisting of di-(tocopheryl) phosphate, di-(tocopheryl) phosphate monosodium salt, and a mixture thereof. 4. The carrier of claim 1, wherein the mono-(tocopheryl) phosphate and di-(tocopheryl) phosphate are present in the mixture in a ratio of at least 2:1. 5. The carrier of claim 1, wherein the hydrophobic vehicle is an oil or a wax. 6. The carrier of claim 5, wherein the hydrophobic vehicle is an edible oil, a vegetable oil, a fruit oil, a seed oil, a grain oil, a nut oil or a polyunsaturated oil containing polyunsaturated fatty acids, an essential or therapeutically-active oil, a silicone oil, or an organic liquid. 7. The carrier of claim 5, wherein the hydrophobic vehicle is beeswax. 8. A formulation comprising the carrier of claim 1 and a nutraceutical or cosmeceutical active. 9. The formulation of claim 8, wherein the formulation is for topical, enteral or parenteral administration. 10. The formulation of claim 9, wherein the formulation is for epicutaneous, oral or transdermal administration. 11. The formulation of claim 8, wherein the nutraceutical and/or cosmeceutical active is selected from the group consisting of vitamins, minerals, amino acids, herbs or other botanicals, enzymes, prebiotics, ubiquinone, ubiquinol, omega-3 fatty acids, lycopene, resveratrol, vitamin E, vitamin D, β-carotene, lutein, zeaxanthin and sodium selenite. 12. The carrier of claim 1, wherein the mono-(tocopheryl) phosphate and di-(tocopheryl) phosphate are present in the mixture in a ratio within a range of about 4:1 to about 1:4. 13. The carrier of claim 1, wherein the mono-(tocopheryl) phosphate and di-(tocopheryl) phosphate are present in the mixture in a ratio within a range of about 6:4 to about 8:2. 14. The carrier of claim 1, wherein the carrier comprises the non-neutralised tocopheryl phosphate in an amount from about 0.1% w/w up to about 5% w/w of the total concentration of the carrier. 15. The carrier of claim 1, wherein the carrier comprises the non-neutralised tocopheryl phosphate in an amount from about 0.01% w/w up to about 5% w/w of the total concentration of the carrier. 16. The carrier of claim 1, wherein the carrier comprises the hydrophobic vehicle in an amount of at least about 90.5% w/w of the total concentration of the carrier. 17. The carrier of claim 1, wherein the carrier comprises the hydrophobic vehicle in an amount of at least about 99.0% w/w, of the total concentration of the carrier. 18. The carrier of claim 5, wherein the hydrophobic vehicle is an oil selected from vegetable oils, fruit oils, seed oils, grain oils, and nut oils.
연구과제 타임라인
LOADING...
LOADING...
LOADING...
LOADING...
LOADING...
이 특허에 인용된 특허 (85)
Terren Nadia,FRX ; Michelet Jacques,FRX ; Perrin Martine,FRX, Acidic composition based on lipid vesicles and its use in topical application.
Lhner Manfred (Bonn DEX) Posselt Klaus (Bonn DEX) Vogtle-Junkert Ute (Alfter DEX) Wagener Hans H. (Meckenheim DEX), Agents for the treatment of severe pain and preparation of said agents.
Challis Brian Christopher,GB3 ; Guthrie Walter Graham,GB3 ; Roper David Vincent,GB3 ; Trew David Frank,GB3, Chemical compositions for inhibiting nitrosation reaction in toiletries and cosmetics.
Kenneth B Kirby ; Berno I. R. Pettersson, Jr., Compositions for rapid and non-irritating transdermal delivery of pharmaceutically active agents and methods for formulating such compositions and delivery thereof.
Lubkin Virginia (One Blackstone Pl. New York NY 10471), Drugs for topical application of sex steroids in the treatment of dry eye syndrome, and methods of preparation and appli.
Belly Robert T. (Ithaca NY) Scensny Patricia M. (Rochester NY) Wu Annie L. (Penfield NY) Chen Chung-yuan (Rochester NY), Hydrolyzable compounds which release electron transfer agents and analytical use of same.
Sanjay Kumar IN; Rashmita Sahoo IN; Paramvir Singh Ahuja IN, Isozyme of autoclavable superoxide dismutase (SOD), a process for the identification and extraction of the SOD in cosmetic, food and pharmaceutical compositions.
Palepu, Nagesh; Kessler, Dean; Tustian, Alexander K.; Quay, Steven C.; Constantinides, Panayiotis P.; Lambert, Karel J., Method for treating colorectal carcinoma using a taxane/tocopherol formulation.
Ito Shinobu,JPX ; Ogata Eiji,JPX, Method of administering vitamin E to animals and compositions containing tocopheryl phosphates and salts thereof for animals.
Lucas Juliet Marie ; Trinh Toan ; Dodd Michael Thomas ; Bartolo Robert Gregory, Methods for controlling environmental odors on the body using compositions comprising uncomplexed cyclodextrins.
Uphues Guenter (Monheim DEX) Ploog Uwe (Haan DEX) Bischof Klaudia (Werne DEX), Process for the production and isolation of monoalkyl phosphoric acid esters.
Baldwin William S. (Minneapolis MN) Willging Stephen M. (Minneapolis MN) Siegel Brock M. (Minneapolis MN), Production of d-alpha-tocopherol from natural plant sources.
Schor Joseph M. (Locust Valley NY) Nigalaye Ashok (Elmhurst NY) Gaylord Norman G. (New Providence NJ), Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose.
Manning Mark C. ; Randolph Theodore W. ; Shefter Eli ; Falk ; III Richard F., Solubilization of pharmaceutical substances in an organic solvent and preparation of pharmaceutical powders using the s.
Bernard Dominique (Paris FRX) Nguyen Quang Lan (Antony FRX), Stabilized cosmetic or dermatological composition containing several precursors of the same active agent in order to max.
Bob G. Sanders ; Kimberly Kline ; Laurence Hurley ; Robb Gardner ; Marla Menchaca ; Weiping Yu ; Puthucode N. Ramanan ; Shenquan Liu ; Karen Israel, Tocopherols, tocotrienols, other chroman and side chain derivatives and uses therof.
Kurihara-Bergstrom Tamie (New City NY) Liu Puchun (Storrs CT), Transdermal administation of ionic pharmaceutically active agents via aqueous isopropanol.
Weissman Donald L. ; Rosenbaum Jerry, Treatment and prevention of cardiovascular diseases with help of aspirin, antioxidants, niacin, and certain B vitamins.
Meybeck Alain (Courbevoie FRX) Bonte Frederic (Courbevoie FRX) Marechal Christian (Paris FRX), Use of a
상세보기
Meybeck Alain (Courbevoie FRX) Dumas Marc (Colombes FRX) Bonte Frederic (Courbevoie FRX) Marechal Christian (Paris FRX), Use of a tocopherol phosphate or one of its derivatives for the preparation of cosmetic or pharmaceutical compositions a.
Meybeck Alain (Courbevoie FRX) Dumas Marc (Colombes FRX) Bonte Frederic (Courbevoie FRX) Marechal Christian (Paris FRX), Use of a tocopherol phosphate or one of its derivatives, for the preparation of cosmetic or pharmaceutical compositions.
Stella Valentino ; Krise Jeffrey P. ; Zygmunt Jan J. ; Georg Ingrid Gunda, Water soluble prodrugs of secondary and tertiary amine containing drugs and methods of making thereof.
Hong Jong Eon,KRX ; Lee Ki Hwa,KRX ; Cho Jun Chul,KRX ; Lee Jang Sob,KRX ; Lee Jung No,KRX ; Chun Ji Min,KRX ; Jang Dong Il,KRX ; Lee Ok Sob,KRX ; Lee Sang Rhin,KRX, Water-in-stable L-ascorbic acid derivative and a method for preparation thereof, and a skin-whitening cosmetic compositi.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.