IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0674203
(2017-08-10)
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등록번호 |
US-10085836
(2018-10-02)
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발명자
/ 주소 |
- Carpentier, Alain F.
- Lam, Hung L.
- Lafrance, Hugues
|
출원인 / 주소 |
- Edwards Lifesciences Corporation
|
대리인 / 주소 |
|
인용정보 |
피인용 횟수 :
0 인용 특허 :
181 |
초록
▼
A prosthetic mitral valve with a compressible and expandable stent that, when expanded, is circumferentially oval, elliptical, or D-shaped, with a major axis and a minor axis ratio of from about 3:4 to about 4:5. Embodiments of the stent comprise three commissure regions disposed towards an outflow
A prosthetic mitral valve with a compressible and expandable stent that, when expanded, is circumferentially oval, elliptical, or D-shaped, with a major axis and a minor axis ratio of from about 3:4 to about 4:5. Embodiments of the stent comprise three commissure regions disposed towards an outflow end and three curved cusp regions between adjacent commissure regions. Three flexible leaflets are attached to the commissure regions in a tri-foil configuration. Embodiments of the prosthetic mitral valve include an atrial ring disposed at the inflow end of the stent.
대표청구항
▼
1. A prosthetic mitral valve comprising: an inflow end, an outflow end, and a central flow axis extending from the inflow end to the outflow end;a cloth-covered ring disposed at the inflow end of the prosthetic mitral valve, the ring comprising a plurality of cells, an inflow edge of the ring contou
1. A prosthetic mitral valve comprising: an inflow end, an outflow end, and a central flow axis extending from the inflow end to the outflow end;a cloth-covered ring disposed at the inflow end of the prosthetic mitral valve, the ring comprising a plurality of cells, an inflow edge of the ring contoured to match a contour of a left atrium adjacent to a native mitral annulus, the ring configured for positioning on an atrial side of the native mitral valve annulus and for holding the prosthetic mitral valve in place;a compressible and expandable base structure extending from the ring towards the outflow end of the prosthetic mitral valve, the base structure when expanded, being circumferentially D-shaped with a major axis longer than a minor axis thereof, the base structure dimensioned for placement within the native mitral valve annulus, the base structure having a larger diameter towards the inflow end of the prosthetic mitral valve and a smaller diameter towards the outflow end of the prosthetic mitral valve, the base structure comprising a stent including three commissure regions and three cusp regions, the cusp regions of the stent extending towards the inflow end of the prosthetic mitral valve past an outflow portion of the cloth-covered ring;a cloth cover disposed over the base structure; andthree flexible tissue leaflets in a tri-foil configuration, the leaflets projecting towards the flow axis, the leaflets secured to the stent along the cusp and commissure regions thereof. 2. The prosthetic mitral valve of claim 1, wherein the cloth covering the ring is polyethylene terephthalate. 3. The prosthetic mitral valve of claim 1, wherein the inflow edge of the ring is scalloped. 4. The prosthetic mitral valve of claim 1, wherein the cloth disposed over the base structure is polyethylene terephthalate. 5. The prosthetic mitral valve of claim 1, wherein the tissue leaflets are bovine pericardium. 6. A prosthetic mitral valve comprising: an inflow end, an outflow end, and a central flow axis extending from the inflow end to the outflow end;a ring disposed at the inflow end of the prosthetic mitral valve, the ring configured for positioning on an atrial side of a native mitral valve annulus and for holding the prosthetic mitral valve in place;a compressible and expandable base structure extending from the ring towards the outflow end of the prosthetic mitral valve, the base structure when expanded, being circumferentially oval, elliptical, or D-shaped with a major axis longer than a minor axis thereof, the base structure dimensioned for placement within the native mitral valve annulus, the base structure having a larger diameter towards the inflow end of the prosthetic mitral valve and a smaller diameter towards the outflow end of the prosthetic mitral valve, the base structure comprising a stent including three commissure regions and three cusp regions, the cusp regions of the stent extending towards the inflow end of the prosthetic mitral valve past an outflow portion of the cloth-covered ring; andthree flexible leaflets in a tri-foil configuration, the leaflets projecting towards the flow axis, the leaflets secured to the stent along the cusp and commissure regions thereof. 7. The prosthetic mitral valve of claim 6, wherein the ring further comprises a cover comprising cloth, biocompatible fabric, or polyester terephthalate. 8. The prosthetic mitral valve of claim 6, wherein the ring comprises a plurality of cells. 9. The prosthetic mitral valve of claim 6, wherein an inflow edge of the ring is contoured to match a contour of a left atrium adjacent to the native mitral annulus. 10. The prosthetic mitral valve of claim 9, wherein the inflow edge of the ring is scalloped. 11. The prosthetic mitral valve of claim 6, wherein the base structure is circumferentially D-shaped. 12. The prosthetic mitral valve of claim 6, wherein a ratio of the minor axis to the major axis of the stent is from about 3:4 to about 4:5. 13. The prosthetic mitral valve of claim 6, wherein the commissure regions comprise first and second commissure posts disposed substantially symmetrically about the minor axis, and a third commissure post disposed substantially on the minor axis. 14. The prosthetic mitral valve of claim 6, wherein the commissure regions comprises three commissure posts. 15. The prosthetic mitral valve of claim 6, wherein the commissure regions comprises commissure posts angled radially inwards towards the flow axis. 16. The prosthetic mitral valve of claim 6, further comprising a cover disposed over the base structure. 17. The prosthetic mitral valve of claim 16, wherein the cover comprises at least one of cloth, biocompatible fabric, and polyester terephthalate. 18. The prosthetic mitral valve of claim 6, wherein the tissue leaflets are bovine pericardium.
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