System and method to identify sources associated with biological rhythm disorders
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61B-005/024
A61B-005/042
A61B-005/00
A61B-005/046
출원번호
US-0869687
(2015-09-29)
등록번호
US-10098560
(2018-10-16)
발명자
/ 주소
Narayan, Sanjiv
Briggs, Carey Robert
Sehra, Ruchir
출원인 / 주소
The Regents of the University of California
대리인 / 주소
Musick, Eleanor
인용정보
피인용 횟수 :
0인용 특허 :
155
초록▼
A system and method are provided to define a driver of a source associated with a cardiac rhythm disorder of a human heart. A plurality of cardiac signals associated with sensors arranged spatially in relation to an area of the heart are processed to determine a sequence of arcs of rotation in relat
A system and method are provided to define a driver of a source associated with a cardiac rhythm disorder of a human heart. A plurality of cardiac signals associated with sensors arranged spatially in relation to an area of the heart are processed to determine a sequence of arcs of rotation in relation to the sensors over a time interval. Rotational directions of the arcs of rotation in the sequence are determined. The area of the heart is identified as controlling the source when the rotational directions of the arcs of rotation in the sequence continue in a same rotational direction in excess of a threshold.
대표청구항▼
1. A method of identifying an area of a human heart, the area associated with control of a source of a cardiac rhythm disorder of the human heart, the method comprising: processing a plurality of cardiac signals associated with sensors arranged spatially in relation to the area of the heart to deter
1. A method of identifying an area of a human heart, the area associated with control of a source of a cardiac rhythm disorder of the human heart, the method comprising: processing a plurality of cardiac signals associated with sensors arranged spatially in relation to the area of the heart to determine at least one sequence of activation in relation to the sensors over a time interval, the area comprising a first region and a second region associated with the source;determining a rotational direction of the at least one sequence of activation; andidentifying the first region as associated with controlling the second region when the at least one sequence of activation continues to rotate in the rotational direction with a substantial degree of rotation over the time interval as indicated by a rotational counter incremented in excess of a threshold. 2. The method of claim 1, wherein the sensors define vertices of the area of the heart. 3. The method of claim 2, wherein the area comprises a plurality of areas of the heart defined by the vertices, the plurality of areas associated with controlling the source of the cardiac rhythm disorder. 4. The method of claim 1, wherein the method further comprises generating an indicator associated with the area of the heart as controlling the source. 5. The method of claim 4, wherein the method further comprises corresponding the indicator to the sensors arranged spatially in relation to the area of the heart. 6. The method of claim 5, wherein corresponding the indicator to the sensors arranged spatially in relation to the area of the heart comprises overlaying the indicator over a representation of the plurality of cardiac signals. 7. The method of claim 1, wherein determining the rotational direction of the at least one sequence of activation further comprises: determining arcs of rotation of the at least one sequence in relation to the sensors over the time interval; anddetermining rotational directions of the arcs of rotation. 8. The method of claim 7, wherein identifying the area of the heart as associated with controlling the source further comprises determining that the rotational directions of the arcs of rotation continue in the rotational direction in excess of the threshold. 9. The method of claim 7, wherein determining a rotational direction of an arc of rotation comprises: selecting a first cardiac signal and a second cardiac signal from the plurality of cardiac signals;determining indices of rotational activity among the first cardiac signal and the second cardiac signal at a plurality of time points during the time interval; andcombining the indices of rotational activity to define the rotational direction of the arc of rotation. 10. The method of claim 9, wherein determining an index of rotational activity comprises: calculating a phase difference among the first cardiac signal and the second cardiac signal at a time point of the time interval; anddetermining whether the phase difference is less than or equal to a first phase threshold, or whether the phase difference is greater than a second phase threshold;incrementing the phase difference by a phase value when the phase difference is less than or equal to the first phase threshold; anddecrementing the phase difference by the phase value when the phase difference is greater than the second phase threshold. 11. The method of claim 10, wherein combining the indices of rotational activity comprises summing calculated phase differences, as incremented or decremented, at the plurality of time points of the time interval. 12. The method of claim 1, wherein the method further comprises: performing processing, determining and identifying over a plurality of time intervals; anddetermining persistence of the identified area as controlling the source when the at least one sequence of activation continues to rotate in the rotational direction over the plurality of time intervals. 13. The method of claim 12, wherein the method further comprises generating an indicator associated with the persistence of the identified area as associated with controlling the source. 14. The method of claim 13, wherein the method further comprises corresponding the indicator to the sensors arranged spatially in relation to the area of the heart. 15. The method of claim 14, wherein corresponding the indicator to the sensors arranged spatially in relation to the area of the heart comprises overlaying the indicator over representations of the plurality of cardiac signals associated with the plurality of time intervals. 16. A system to identify an area of a human heart, the area associated with control of a source of a cardiac rhythm disorder of the human heart, the system comprising: a processing device; anda memory device to store a plurality of instructions that, when executed by the processing device, cause the processing device to perform operations comprising: processing a plurality of cardiac signals associated with sensors arranged spatially in relation to the area of the heart to determine at least one sequence of activation in relation to the sensors over a time interval, the area comprising a first region and a second region associated with the source;determining a rotational direction of the at least one sequence of activation; andidentifying the first region as associated with controlling the second region when the at least one sequence of activation continues to rotate in the rotational direction with a substantial degree of rotation over the time interval as indicated by a rotational counter incremented in excess of a threshold. 17. The system of claim 16, wherein the sensors define vertices of the area of the heart. 18. The system of claim 17, wherein the area comprises a plurality of areas of the heart defined by the vertices, the plurality of areas associated with controlling the source of the cardiac rhythm disorder. 19. The system of claim 16, wherein the operations further comprise generating an indicator associated with the area of the heart as controlling the source. 20. The system of claim 19, wherein the operations further comprise corresponding the indicator to the sensors arranged spatially in relation to the area of the heart. 21. The system of claim 20, wherein the operations further comprise overlaying the indicator over a representation of the plurality of cardiac signals. 22. The system of claim 16, wherein the operations to determine the rotational direction of the at least one sequence of activation comprise: determining arcs of rotation of the at least one sequence in relation to the sensors over the time interval; anddetermining rotational directions of the arcs of rotation. 23. The system of claim 22, wherein the operations to identify the area of the heart as associated with controlling the source comprise determining that the rotational directions of the arcs of rotation continue in the rotational direction in excess of the threshold. 24. The system of claim 23, wherein the operations to determine a rotational direction of an arc of rotation comprise: selecting a first cardiac signal and a second cardiac signal from the plurality of cardiac signals;determining indices of rotational activity among the first cardiac signal and the second cardiac signal at a plurality of time points during the time interval; andcombining the indices of rotational activity to define the rotational direction of the arc of rotation. 25. The system of claim 24, wherein the operations to determine an index of rotational activity comprise: calculating a phase difference among the first cardiac signal and the second cardiac signal at a time point of the time interval; anddetermining whether the phase difference is less than or equal to a first phase threshold, or whether the phase difference is greater than a second phase threshold;incrementing the phase difference by a phase value when the phase difference is less than or equal to the first phase threshold; anddecrementing the phase difference by the phase value when the phase difference is greater than the second phase threshold. 26. The system of claim 24, wherein the operation to combine the indices of rotational activity comprise summing calculated phase differences, as incremented or decremented, at the plurality of time points of the time interval. 27. The system of claim 16, wherein the operations further comprise: performing processing, determining and identifying over a plurality of time intervals; anddetermining persistence of the identified area as controlling the source when the at least one sequence of activation continues to rotate in the rotational direction over the plurality of time intervals. 28. The system of claim 27, wherein the operations further comprise generating an indicator associated with the persistence of the identified area as controlling the source. 29. The system of claim 28, wherein the operations further comprise corresponding the indicator to the sensors arranged spatially in relation to the area of the heart. 30. The system of claim 29, wherein the operations to correspond the indicator to the sensors arranged spatially in relation to the area of the heart comprise overlaying the indicator over representations of the plurality of cardiac signals associated with the plurality of time intervals.
연구과제 타임라인
LOADING...
LOADING...
LOADING...
LOADING...
LOADING...
이 특허에 인용된 특허 (155)
Desai Jawahar M. (4141 Cowell Blvd. ; No. 38 Davis CA 95616), Apparatus and method for cardiac ablation.
White Harley (Redmond WA) Bocek Joseph M. (Seattle WA), Automatic gain control and method for enabling detection of low and high amplitude depolarization activation waves of th.
Robert W. Stadler ; Shannon Nelson, Axis shift analysis of electrocardiogram signal parameters especially applicable for multivector analysis by implantable medical devices, and use of same.
Stadler Robert W. ; Nelson Shannon, Axis shift analysis of electrocardiogram signal parameters especially applicable for multivector analysis by implantable medical devices, and use of same.
Branham Barry H. (Ballwin MO) Cox James L. (Ladue MO) Boineau John P. (Ladue MO) Schuessler Richard B. (Ballwin MO), Computerized three-dimensional cardiac mapping with interactive visual displays.
Shen Xiguang (North Point CNX) Feng Genquan (Beijing CNX) Lian Ruan (Beijing CNX) Wang Changqing (Beijing CNX) Lian Jing (Shenzhen CNX) Liu Chi (Guangzhou CNX) Lai Shizhong (Guangzhou CNX) Yang Jilin, Correlative analysis in multi-domain processing of cardiac signals.
Sweeney,Robert J.; Lovett,Eric G., Curvature based method for selecting features from an electrophysiologic signal for purpose of complex identification and classification.
Ackmann James J. (Wauwatosa WI) Christman Norbert T. (Wauwatosa WI) Ebert Thomas J. (Glendale WI), Impedance cardiograph and method of operation utilizing peak aligned ensemble averaging.
Dupree, Daniel A.; Nguyen, Tuan; Panescu, Dorin; Whayne, James G.; McGee, David; Swanson, David K., Interactive systems and methods for controlling the use of diagnostic or therapeutic instruments in interior body regions.
Dupree, Daniel A.; Nguyen, Tuan; Panescu, Dorin; Whayne, James G.; McGee, David; Swanson, David K., Interactive systems and methods for controlling the use of diagnostic or therapeutic instruments in interior body regions.
Hauck,John A.; Schweitzer,Jeff A.; Craven,Michael; Afonso,Valtino; Cotner,Holly; Callaghan,Frank; Schultz,John, Method and apparatus for catheter navigation and location and mapping in the heart.
Ghanem, Raja N.; Stadler, Robert W.; Zhang, Xusheng; Greenhut, Saul E.; Kleckner, Karen J.; Krause, Paul G.; Mahajan, Veerdhaval, Method and apparatus for detecting arrhythmias in a medical device.
Ghanem, Raja N.; Stadler, Robert W.; Zhang, Xusheng; Kleckner, Karen J.; Krause, Paul G., Method and apparatus for detecting arrhythmias in a medical device.
Ghanem, Raja N.; Stadler, Robert W.; Zhang, Xusheng; Kleckner, Karen J.; Krause, Paul G., Method and apparatus for detecting arrhythmias in a medical device.
Stadler Robert ; Nelson Shannon ; Stylos Lee ; Sheldon Todd J., Method and apparatus for filtering electrocardiogram (ECG) signals to remove bad cycle information and for use of physiologic signals determined from said filtered ECG signals.
Gunderson, Bruce D.; Patel, Amisha S.; Bounds, Chad A.; Brown, Mark L., Method and apparatus for identifying oversensing using far-field intracardiac electrograms and marker channels.
Gunderson, Bruce D.; Patel, Amisha S.; Bounds, Chad A.; Brown, Mark L., Method and apparatus for identifying oversensing using far-field intracardiac electrograms and marker channels.
Bj?rling, Anders; Hedberg, Sven-Erik; Lindegren, Ulf; Lindgren, Anders, Method and circuit for detecting cardiac rhythm abnormalities by analyzing time differences between unipolar signals from a lead with a multi-electrode tip.
Efimov, Igor R.; Krinski, Valentin I.; Nikolski, Vladimir P., Method for low-voltage termination of cardiac arrhythmias by effectively unpinning anatomical reentries.
Efimov, Igor R.; Krinski, Valentin I.; Nikolski, Vladimir P., Method for low-voltage termination of cardiac arrhythmias by effectively unpinning anatomical reentries.
Goldreyer Bruce N. (30311 Palos Verdes Dr. East Rancho Palos Verdes CA 90274), Method for spatially specific electrophysiological sensing for mapping, pacing and ablating human myocardium and a cathe.
Svenson Robert H. (Charlotte NC) King Wendell (North Oaks MN), Process of identification of a ventricular tachycardia (VT) active site and an ablation catheter system.
Tarjan,Peter P.; Lu,Chih Cheng; Besio,Walter, Single or multi-mode cardiac activity data collection, processing and display obtained in a non-invasive manner.
Ciaccio, Edward J.; Wit, Andrew L.; Tosti, Alexis Christine, System and method for determining reentrant ventricular tachycardia isthmus location and shape for catheter ablation.
Ciaccio,Edward J.; Wit,Andrew L.; Tosti,Alexis Christine, System and method for determining reentrant ventricular tachycardia isthmus location and shape for catheter ablation.
Rudy,Yoram; Ramanathan,Charulatha; Ghanem,Raja; Jia,Ping, System and methods for noninvasive electrocardiographic imaging (ECGI) using generalized minimum residual (GMRes).
Swanson David K. ; Whayne James G. ; Panescu Dorin, Systems and methods for acquiring making time-sequential measurements of biopotentials sensed in myocardial tissue.
Panescu Dorin ; Swanson David K. ; Mirotznik Mark S. ; Schwartzman David S. ; Foster Kenneth R., Systems and methods for examining the electrical characteristic of cardiac tissue.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.